RNF212B (ring finger protein 212B)

Gene: RNF212B (ring finger protein 212B) Sus scrofa

Analyze

Symbol:

RNF212B

Name:

ring finger protein 212B

RGD ID:

14123507

Description:

ENCODES a protein that exhibits metal ion binding (inferred); SUMO transferase activity (inferred); INVOLVED IN homologous chromosome pairing at meiosis (inferred); protein sumoylation (inferred); reciprocal meiotic recombination (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); Female Infertility (ortholog); lysinuric protein intolerance (ortholog); FOUND IN synaptonemal complex (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	75,796,882 - 75,829,620 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	75,798,895 - 75,831,455 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,916,406 - 80,942,492 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

Female Infertility (ISO)

lysinuric protein intolerance (ISO)

Specific Granule Deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

homologous chromosome pairing at meiosis (IEA)

protein sumoylation (IEA)

reciprocal meiotic recombination (IEA)

Cellular Component

synaptonemal complex (IEA)

Molecular Function

metal ion binding (IEA)

SUMO transferase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

RNF212B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	75,796,882 - 75,829,620 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	75,798,895 - 75,831,455 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,916,406 - 80,942,492 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF212B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	23,185,336 - 23,273,477 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	23,185,316 - 23,273,477 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	23,654,545 - 23,742,686 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	22,724,385 - 22,809,408 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	3,572,254 - 3,602,270 (+)	NCBI		Celera
Cytogenetic Map	14	q11.2	NCBI
HuRef	14	3,823,625 - 3,860,155 (+)	NCBI		HuRef
CHM1_1	14	23,705,740 - 23,742,151 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	17,386,004 - 17,474,456 (+)	NCBI		T2T-CHM13v2.0

Rnf212b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	55,020,798 - 55,091,567 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	55,051,598 - 55,091,565 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	54,783,341 - 54,854,110 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	54,814,141 - 54,854,108 (+)	Ensembl	GRCm38		mm10	GRCm38
Celera	14	52,576,109 - 52,657,147 (+)	NCBI		Celera
Cytogenetic Map	14	C2- C3	NCBI

Rnf212b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	32,244,620 - 32,292,358 (+)	NCBI		GRCr8
mRatBN7.2	15	28,274,629 - 28,321,093 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	28,244,083 - 28,321,347 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	15	33,430,269 - 33,509,698 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	15	37,318,544 - 37,396,548 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	15	27,822,288 - 27,900,302 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

Rnf212b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955409	37,041,751 - 37,095,179 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF212B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	24,668,210 - 24,706,850 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	23,884,700 - 23,923,340 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	4,056,671 - 4,093,210 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	22,153,247 - 22,188,319 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	22,153,247 - 22,188,319 (+)	Ensembl	panpan1.1		panPan2

RNF212B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	3,509,481 - 3,552,600 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	3,509,638 - 3,544,740 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	3,457,882 - 3,500,161 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	3,617,537 - 3,659,814 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	3,617,689 - 3,652,792 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	3,308,549 - 3,351,225 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	3,369,825 - 3,412,538 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	3,632,387 - 3,674,674 (+)	NCBI		UU_Cfam_GSD_1.0

Rnf212b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	35,272,431 - 35,302,846 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936722	1,088,424 - 1,116,352 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936722	1,086,237 - 1,116,352 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF212B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	23,609,267 - 23,646,333 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	23,611,965 - 23,644,935 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	22,773,394 - 22,861,081 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf212b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624820	9,268,727 - 9,322,963 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RNF212B
612 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	endocrine system	nervous system	renal system
High
Medium
Low			6	2
Below cutoff	1	1	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021099238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU633625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000022671 ⟹ ENSSSCP00000023583

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	75,796,882 - 75,829,620 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000070230 ⟹ ENSSSCP00000062376

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	75,796,882 - 75,816,311 (-)	Ensembl

RefSeq Acc Id:

XM_021099238 ⟹ XP_020954897

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	75,798,895 - 75,831,455 (-)	NCBI

Sequence:

show sequence

ACATCGATCACACACCTCAGCGGGCCACGCCCAGCTTCTTGTCGCTCCGGAGTGCCAGGTTTGC
TGTTTTTTTCCCGCCATTTTTAGCTTTTTGAGGAGAACTGGTTGTTTTAGGTGAGATCCGAGGC
TTTCTGAGAATCACGGCGGCCAAACGGAATGGATTGGTTTCACTGCAACCGGTGTTTCCGAAAA
GATGGGGCCCATTTCTTTGTTACCAGCTGTGGTCATATTTTCTGTAAAAAATGTGTGACTCTAG
AAAAATGTTCTATCTGCGGAACTGCCTGCAAGCATCTGGCTCTTTCTGATAGTCTGAAACCTCA
GGAGAAGATGTACTTCAAAAGCCCTGTGGAGACAGCTTTGCAGTATTTTAGTCACATCTCTCAG
GTGTGGAGTTTCCAGAAGAAACAAACAGATCTCCTCATTGCCTTTTTTAAGCATAGAATTACAA
AGTTAGAAGCATCCTTACAGGAGGCACAGCAAACATTGACCAACAAGGACAAAGAGCTGTCAGT
CTTAAGGAAAGAGAATGGAGAACTGAAGAAATTTCTAGCCATCCTAAAGGAATCTCCAAGTTGG
TACCAAGGAAGCAGATCAACCACACCTCGACCAGTGGGCATTACCTCTCCATCACAGTCAGTTA
CCCCACGACCCAGTTCTCAGCATAGTAGCCAAGTGGTCAGTCGATCCTCCTCAGTGGAGTCTAT
CCCTTATAGAGTGGCTGGCTTTAGTAACTTGGGACAAGGAGTCAGAGGCCTGCAGGCTAGGAGC
ACTCCCAGAGACTCTTATACCGAAACCCCTTCACCAGCTTCTACTCACAGCCTGTCTTATAGAC
CTTCATCTGCCTCCTCCGGACAGGGGATTTTTTCTTTCAGACCATCCCTAAATGGTGGGGATTC
AGATCTCACAAGAGTCCTCACCTCCAACAATTCAGGTCAGAGAGAGAGCAGAACCACCCTAGAG
AGTCTTCCTGGTTTCCAGCTACCAGTCCTGCAGAATCTCTACCAACAGAGGCAGATGGGATTAG
CCAGGGGGAAAGAAGTATGGAACACTCCCAGATAGACCATGTTCCAGGTCTGATCTATATATAC
GGCTGAAGGACGGACGTTAGCATCTAAACTCGTTTAGACCTGATGGCCTGGGAAAATGCACCCC
TGCCTTATTTCCTGGTTTCACTCTGTATCTTCTTTCAGTCTTTACCCTGTATACCCTGTATTAC
TTCCTACAAAAGGGATCAGGTCAGTGCTTCAGAAAGATGTCAGTATCTTTCCTATAAGATATAC
GTAGCTCCCTTATTTCCTACAACTTGAAACAAAGGTTATAAAAACAATTCTTGGCATGGGGGGG
TGATGGTGGTAATATGCTCATTAACCGTGTTTTATTTCCGGATTTCACTTTTTAGCTTTGGATA
TATTCTCCCATTGCCAGTGTTAACAAGCAAAAACTCTGTTCCTTGCCCTAATTGAGTATACGTT
TTCTGTTTGCCTCTTGTTTCCTCCATGCCTGGTTACTATTAAATATGTTAATTTTTCTTTCTGT
CTGGTACCAGTTGGAGGCACAGGCTTTCAGCTTACTAAAGTACACAGATAATAAAATAAAGAGG
ATGCCCTTTTACTGCTACTGCAACTATACTGGTATTACAAGCTCTAGAATGGTGGGATGGGCAA
AGAACACTACCACTGAGATCGAACATTTATTTTTCTTTGGGTACCAAGGGGTAAAATGAGGAGT
TAAGGAGTTCCTGTCGTGGCCGCAGTGGTTAATGAATCTGACTAGGAACCATGAGGTTGCGGGT
TCGGTCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_020954897	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00070036438.1
	ENSSSCP00070036443.1

RefSeq Acc Id:

XP_020954897 ⟸ XM_021099238

- UniProtKB:

A0A4X1V6N9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDWFHCNRCFRKDGAHFFVTSCGHIFCKKCVTLEKCSICGTACKHLALSDSLKPQEKMYFKSPV
ETALQYFSHISQVWSFQKKQTDLLIAFFKHRITKLEASLQEAQQTLTNKDKELSVLRKENGELK
KFLAILKESPSWYQGSRSTTPRPVGITSPSQSVTPRPSSQHSSQVVSRSSSVESIPYRVAGFSN
LGQGVRGLQARSTPRDSYTETPSPASTHSLSYRPSSASSGQGIFSFRPSLNGGDSDLTRVLTSN
NSGQRESRTTLESLPGFQLPVLQNLYQQRQMGLARGKEVWNTPR

hide sequence

RefSeq Acc Id:

ENSSSCP00000062376 ⟸ ENSSSCT00000070230

RefSeq Acc Id:

ENSSSCP00000023583 ⟸ ENSSSCT00000022671

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000026237	Ensembl
	ENSSSCG00070021795	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00070043307.1	UniProtKB/TrEMBL
	ENSSSCT00070043312.1	UniProtKB/TrEMBL
InterPro	Vilya/Cst9/RNF212	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
NCBI Gene	RNF212B	ENTREZGENE
PANTHER	PTHR22663	UniProtKB/TrEMBL
	RING FINGER PROTEIN 212B	UniProtKB/TrEMBL
PROSITE	ZF_RING_1	UniProtKB/TrEMBL
UniProt	A0A4X1V6N9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0JLT4_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:92381	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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