GPC1 (glypican 1) - Rat Genome Database

Name: GPC1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: GPC1 (glypican 1) Sus scrofa

Analyze

Symbol:

GPC1

Name:

glypican 1

RGD ID:

14123221

Description:

ENCODES a protein that exhibits collagen V binding (ortholog); INVOLVED IN myelin assembly (ortholog); Schwann cell differentiation (ortholog); PARTICIPATES IN glypican signaling pathway; Hedgehog signaling pathway; ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

glypican-1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPC1 (glypican 1)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Gpc1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gpc1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpc1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPC1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPC1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpc1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPC1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpc1 (glypican 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,457,669 - 139,484,670 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	139,457,866 - 139,483,704 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	154,436,077 - 154,449,277 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bethlem Myopathy 1A (ISO)

chromosome 2q37 deletion syndrome (ISO)

D-2-hydroxyglutaric aciduria 1 (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

hereditary spastic paraplegia 30 (ISO)

intellectual disability (ISO)

primary hyperoxaluria type 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (IBA,IEA)

heparan sulfate proteoglycan catabolic process (IEA)

myelin assembly (ISO)

negative regulation of fibroblast growth factor receptor signaling pathway (IBA,IEA)

positive regulation of skeletal muscle cell differentiation (IEA)

regulation of protein localization to membrane (IBA,IEA)

regulation of signal transduction (IEA)

Schwann cell differentiation (ISO)

Cellular Component

cell surface (IBA,IEA)

collagen-containing extracellular matrix (IEA)

cytosol (IEA)

extracellular matrix (IEA)

extracellular region (IEA)

membrane raft (IEA)

neuronal cell body (ISO)

nucleoplasm (IEA)

plasma membrane (IEA)

side of membrane (IEA)

synapse (IBA,IEA)

Molecular Function

collagen V binding (ISO)

copper ion binding (IEA)

fibroblast growth factor binding (IBA,IEA)

laminin binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glypican signaling pathway (ISO)

Hedgehog signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GPC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,457,669 - 139,484,670 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	139,457,866 - 139,483,704 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	154,436,077 - 154,449,277 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	240,435,663 - 240,468,076 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	240,435,663 - 240,468,076 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	241,375,080 - 241,407,493 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	241,023,788 - 241,056,168 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	241,095,104 - 241,127,483	NCBI
Celera	2	235,047,069 - 235,079,415 (+)	NCBI		Celera
Cytogenetic Map	2	q37.3	NCBI
HuRef	2	233,131,263 - 233,163,487 (+)	NCBI		HuRef
CHM1_1	2	241,381,165 - 241,413,509 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	240,929,356 - 240,961,704 (+)	NCBI		T2T-CHM13v2.0

Gpc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	92,759,367 - 92,787,933 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	92,759,367 - 92,788,501 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	92,831,645 - 92,860,211 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	92,831,645 - 92,860,779 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	94,728,263 - 94,756,773 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	94,662,092 - 94,690,602 (+)	NCBI		MGSCv36	mm8
Celera	1	95,776,004 - 95,804,554 (+)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	46.6	NCBI

Gpc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	100,843,645 - 100,871,458 (+)	NCBI		GRCr8
mRatBN7.2	9	93,396,234 - 93,424,047 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,396,234 - 93,424,047 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	101,832,104 - 101,859,907 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	106,967,887 - 106,995,694 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,324,039 - 105,351,842 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	99,998,275 - 100,026,818 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	99,998,275 - 100,026,818 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	99,664,180 - 99,692,723 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	90,933,123 - 90,960,752 (+)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

Gpc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955542	947,556 - 968,295 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955542	947,556 - 968,295 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	143,110,895 - 143,143,597 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	143,126,093 - 143,158,562 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	127,684,839 - 127,717,294 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	246,509,247 - 246,523,569 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	246,511,082 - 246,523,569 (+)	Ensembl	panpan1.1		panPan2

GPC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	50,484,554 - 50,492,940 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	50,482,071 - 50,515,877 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	50,936,475 - 50,962,772 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	50,917,330 - 50,943,617 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	50,918,480 - 50,941,977 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	50,759,401 - 50,785,702 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	50,505,447 - 50,531,706 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	50,782,678 - 50,809,060 (+)	NCBI		UU_Cfam_GSD_1.0

Gpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	192,090,303 - 192,100,688 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936745	1,118,732 - 1,127,169 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	126,464,383 - 126,496,686 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	126,464,801 - 126,497,897 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	72,906,497 - 72,938,406 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624847	4,832,488 - 4,853,851 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624847	4,832,610 - 4,853,849 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GPC1
600 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium		1			2
Low	3	3	3	5		23	2	3	1
Below cutoff	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005654198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021075944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01011846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000017819 ⟹ ENSSSCP00000017338

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	139,472,590 - 139,484,670 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000060487 ⟹ ENSSSCP00000047245

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	139,457,669 - 139,484,669 (+)	Ensembl

RefSeq Acc Id:

XM_005654198 ⟹ XP_005654255

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	139,472,827 - 139,483,704 (+)	NCBI

Sequence:

show sequence

GTGACGCTGTCATGTGGCTGGGATGGTGGAGGGGCTTAGGGCTGTCGGTCGGGGTAGAGGAGCG
GCCCCCGAGGGCGGTGGGTGGGGGTACGGGGCTTGTGCCGTGTTCGCAAGCGGAGAGGATGGCG
CTGGAAAGTGGGTCTGCGGCTGCCCCCGATGGACTCCAGGTGAGCACCTGCGGATCTGCCCCCA
GGGCTACACCTGCTGCACCAGCGAGATGGAGGAAAACCTGGCCAACCGCAGCCGGGCCGAGCTG
GAGACCGCCCTCCTGGACAGCAGCCGAGCCTTGCAGGCCACCCTCACCAGCCAGCTGCGGGGCT
TCGACGATCACTTCCAGCGCCTGCTGAACGACTCGGAGCGGACGCTGCAGGAGGCCTTCCCCGG
CGCCTTCGGAGAGCTGTACACGCAGAGCGCCAAGGCCTTCCGGGACCTGTACGCCGAGCTGCGC
CTCTACTACCGCGGCGCCAACCTGCACCTGGAGGAGACGCTGGCCGAGTTCTGGGCCCGCCTGC
TCGAGCGCCTCTTCCGGCAGCTGCACCCCCAGCTGCTGCTGCCCGACGACTACCTGGACTGCCT
GGGCAAGCAGGCCGAGGCGCTGCGGCCCTTCGGGGAGGCCCCGCGCGAGCTGCGCCTGCGCGCC
ACCCGCGCCTTCGTGGCGGCGCGCGCCTTCGTGCAGGGCCTGGGCGTGGCCGGCGACGTGGTCC
GCAAGGTGTCCCAGGTGCCCTTGGGCCCTGAGTGCTCAAGGGCCGTCATGAAGCTGGTGTACTG
CGCGCACTGCCTGGGGGTCCCTGGCGCCCGGCCCTGCCCGGACTACTGCCGCAACGTGCTCAAG
GGATGCCTGGCCAACCAGGCCGACCTGGACGCAGAGTGGAGGAACCTTCTGGACTCCATGGTGC
TCATCACTGACAAGTTCTGGGGCCCGACGGGTGCGGAGAACGTCATTGGCAGCGTGCACTTGTG
GCTGGCAGAGGCCATCAACGCCCTCCAGGACAACAAGGACACACTCACGGCCAAGGTCATCCAG
GGCTGCGGGAACCCCAAGGTGAACCCCCAGGGCCCGGGGCCTGAGGAGAAGCGGCGCCGGGGCA
AGCTGGCACTGCAGGAGAAGCCACCCTCGGGCACGCTGCAGAAGCTGGTCCCCGAAGCCAAGGC
CCAGCTCCGAGATGCCCAGGACTTCTGGATCAGCCTCCCAGGGATGCTGTGCAGTGAGAAGTTG
GCCATGAGCTCAGCCAGTGACGACCGCTGTTGGAACGGGGTGGCCAAGGGCCGGTACCTCCCCG
AGGTGATGGGCGATGGCCTGGCCAACCAGATCAACAACCCCGAGGTGGAGGTGGACGTCACCAA
GCCAGACATGACCGTCCGCCAGCAGATCATGCAGCTCAAGATCATGACCAACCGCCTTCGCAGC
GCCTACAATGGCAACGACGTGGACTTCCAGGATGCCAGTGATGACGGCAGCGGCTCAGGCAGCG
GCGATGGCTGCGCAGACGACGCCTGCGGCCGGAGGGTCAGCAAGAAAAGCTCCAGCTCCCGGAC
GACCCTGACCCACGCCCTCCCCGGCCTGTCGGAACAGGAGGGCCAGAAGACCTCGGCCGCGCGC
TGCCCCCAGCCCTGCCTGTGCCTCTTGCTCCTCCCTGTCCTCGCCCTGGTCCTCGCAGCATCCA
GGCCCCGGTGGCGGTAACTGCCCCTGAGGCCGAGGCCAAGGACTGACTTTGCCAAAACTCAGAA
CAGACGATATTTAACTTCCTCGCCCTAGTGGCTCCGGGGCGGCACAGGAAGGGACAGCCAGGGA
CCGCGGCTCTGTGACTGTGCTTGGGGCAGGGTGAGGTGGCACCGGTCCCCCAGGCCTGGCTTTG
CCTGCCACCCTGGGTTTTAATTTTGTATGAGGCCCTCAGGTCAGCCAGGAACAGTGTCCCCAAA
AGCCATGCATTTCAGGGACCCCGGGGTCGCTGGTGGCCATCTCCCCCCAGCTTCCCTGCACCAT
TGCAGCAGCACCCAGGCTGGTGAGGAGGCCGCGCGGAGCAGTGTCCTGCTGGAGCTGAGCCCAC
GCCTTCCTCACCGCCCCCGGGGCCCTTGGGGCTCCAGGTGTCTGAAAGCCAGACCCTCCCCTCA
GGTCCTGAGAAGGTCCTATGCATGAG

hide sequence

RefSeq Acc Id:

XM_021075944 ⟹ XP_020931603

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	139,457,866 - 139,483,704 (+)	NCBI

Sequence:

show sequence

GATCGCGCCCCCGCGCCGCGCCGCGCCGCGCCCCGCCCCGCCCCGCGCGCCCCGCCCCGCCCCG
CGCGCCCCTCCCCGCCCCTCTCCCGGGCCGCCGAGGGGCCGGGCCGGGACTGCGCGCTCGCCCG
CCGCGCTCTGGGCCGCCCGAGCGAGCGGCCGGTCCTCGCGCCCCGCGCGCCCCGCGCCCCGCCG
CCGCCGGCTTTTGTTGTCTCCTCCTCCCCTGCGGCCGGCGCCTCTGGACCGCGAGCCGAGTGCG
CCGGGACCTTGGCTCTGCCCTTCGCGGGCCGGGGCTGCGCGGGCCCGGCCGGGGGCGCCGCCGG
CCCCGCCATGGAGCTCCGGGCCCGAGGCTGGTGGCTGCTGTGCGCGGCCGCCGCGCTGGCCGCC
TGCGCTCGCGGGGACCCTGCCAGCAAGAGTCGGAGCTGCGGCGAAGTCCGCCAGATCTACGGGG
CCAAGGGCTTCAGCCTGAGCGACGTGCCCCAGGCGGAGATCTCGGGTGAGCACCTGCGGATCTG
CCCCCAGGGCTACACCTGCTGCACCAGCGAGATGGAGGAAAACCTGGCCAACCGCAGCCGGGCC
GAGCTGGAGACCGCCCTCCTGGACAGCAGCCGAGCCTTGCAGGCCACCCTCACCAGCCAGCTGC
GGGGCTTCGACGATCACTTCCAGCGCCTGCTGAACGACTCGGAGCGGACGCTGCAGGAGGCCTT
CCCCGGCGCCTTCGGAGAGCTGTACACGCAGAGCGCCAAGGCCTTCCGGGACCTGTACGCCGAG
CTGCGCCTCTACTACCGCGGCGCCAACCTGCACCTGGAGGAGACGCTGGCCGAGTTCTGGGCCC
GCCTGCTCGAGCGCCTCTTCCGGCAGCTGCACCCCCAGCTGCTGCTGCCCGACGACTACCTGGA
CTGCCTGGGCAAGCAGGCCGAGGCGCTGCGGCCCTTCGGGGAGGCCCCGCGCGAGCTGCGCCTG
CGCGCCACCCGCGCCTTCGTGGCGGCGCGCGCCTTCGTGCAGGGCCTGGGCGTGGCCGGCGACG
TGGTCCGCAAGGTGTCCCAGGTGCCCTTGGGCCCTGAGTGCTCAAGGGCCGTCATGAAGCTGGT
GTACTGCGCGCACTGCCTGGGGGTCCCTGGCGCCCGGCCCTGCCCGGACTACTGCCGCAACGTG
CTCAAGGGATGCCTGGCCAACCAGGCCGACCTGGACGCAGAGTGGAGGAACCTTCTGGACTCCA
TGGTGCTCATCACTGACAAGTTCTGGGGCCCGACGGGTGCGGAGAACGTCATTGGCAGCGTGCA
CTTGTGGCTGGCAGAGGCCATCAACGCCCTCCAGGACAACAAGGACACACTCACGGCCAAGGTC
ATCCAGGGCTGCGGGAACCCCAAGGTGAACCCCCAGGGCCCGGGGCCTGAGGAGAAGCGGCGCC
GGGGCAAGCTGGCACTGCAGGAGAAGCCACCCTCGGGCACGCTGCAGAAGCTGGTCCCCGAAGC
CAAGGCCCAGCTCCGAGATGCCCAGGACTTCTGGATCAGCCTCCCAGGGATGCTGTGCAGTGAG
AAGTTGGCCATGAGCTCAGCCAGTGACGACCGCTGTTGGAACGGGGTGGCCAAGGGCCGGTACC
TCCCCGAGGTGATGGGCGATGGCCTGGCCAACCAGATCAACAACCCCGAGGTGGAGGTGGACGT
CACCAAGCCAGACATGACCGTCCGCCAGCAGATCATGCAGCTCAAGATCATGACCAACCGCCTT
CGCAGCGCCTACAATGGCAACGACGTGGACTTCCAGGATGCCAGTGATGACGGCAGCGGCTCAG
GCAGCGGCGATGGCTGCGCAGACGACGCCTGCGGCCGGAGGGTCAGCAAGAAAAGCTCCAGCTC
CCGGACGACCCTGACCCACGCCCTCCCCGGCCTGTCGGAACAGGAGGGCCAGAAGACCTCGGCC
GCGCGCTGCCCCCAGCCCTGCCTGTGCCTCTTGCTCCTCCCTGTCCTCGCCCTGGTCCTCGCAG
CATCCAGGCCCCGGTGGCGGTAACTGCCCCTGAGGCCGAGGCCAAGGACTGACTTTGCCAAAAC
TCAGAACAGACGATATTTAACTTCCTCGCCCTAGTGGCTCCGGGGCGGCACAGGAAGGGACAGC
CAGGGACCGCGGCTCTGTGACTGTGCTTGGGGCAGGGTGAGGTGGCACCGGTCCCCCAGGCCTG
GCTTTGCCTGCCACCCTGGGTTTTAATTTTGTATGAGGCCCTCAGGTCAGCCAGGAACAGTGTC
CCCAAAAGCCATGCATTTCAGGGACCCCGGGGTCGCTGGTGGCCATCTCCCCCCAGCTTCCCTG
CACCATTGCAGCAGCACCCAGGCTGGTGAGGAGGCCGCGCGGAGCAGTGTCCTGCTGGAGCTGA
GCCCACGCCTTCCTCACCGCCCCCGGGGCCCTTGGGGCTCCAGGTGTCTGAAAGCCAGACCCTC
CCCTCAGGTCCTGAGAAGGTCCTATGCATGAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005654255	(Get FASTA)	NCBI Sequence Viewer
	XP_020931603	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017338
	ENSSSCP00000017338.2
	ENSSSCP00000047245
	ENSSSCP00000047245.1
	ENSSSCP00025043119.1
	ENSSSCP00025043194.1
	ENSSSCP00035043293.1
	ENSSSCP00040034000.1
	ENSSSCP00040034071.1
	ENSSSCP00045023028.1
	ENSSSCP00055046861.1
	ENSSSCP00060044088.1
	ENSSSCP00060044125.1
	ENSSSCP00065046833.1

RefSeq Acc Id:	XP_020931603 ⟸ XM_021075944
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D1F7W9 (UniProtKB/TrEMBL), A0A287ATH4 (UniProtKB/TrEMBL), A0A8D2CI14 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELRARGWWLLCAAAALAACARGDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQ GYTCCTSEMEENLANRSRAELETALLDSSRALQATLTSQLRGFDDHFQRLLNDSERTLQEAFPG AFGELYTQSAKAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFRQLHPQLLLPDDYLDCL GKQAEALRPFGEAPRELRLRATRAFVAARAFVQGLGVAGDVVRKVSQVPLGPECSRAVMKLVYC AHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPTGAENVIGSVHLW LAEAINALQDNKDTLTAKVIQGCGNPKVNPQGPGPEEKRRRGKLALQEKPPSGTLQKLVPEAKA QLRDAQDFWISLPGMLCSEKLAMSSASDDRCWNGVAKGRYLPEVMGDGLANQINNPEVEVDVTK PDMTVRQQIMQLKIMTNRLRSAYNGNDVDFQDASDDGSGSGSGDGCADDACGRRVSKKSSSSRT TLTHALPGLSEQEGQKTSAARCPQPCLCLLLLPVLALVLAASRPRWR hide sequence

RefSeq Acc Id:	XP_005654255 ⟸ XM_005654198
- Peptide Label:	isoform X2
- UniProtKB:	F1SIQ5 (UniProtKB/TrEMBL), A0A8D1WUM4 (UniProtKB/TrEMBL), A0A8D1KGL8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVEGLRAVGRGRGAAPEGGGWGYGACAVFASGEDGAGKWVCGCPRWTPGEHLRICPQGYTCCTS EMEENLANRSRAELETALLDSSRALQATLTSQLRGFDDHFQRLLNDSERTLQEAFPGAFGELYT QSAKAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFRQLHPQLLLPDDYLDCLGKQAEAL RPFGEAPRELRLRATRAFVAARAFVQGLGVAGDVVRKVSQVPLGPECSRAVMKLVYCAHCLGVP GARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPTGAENVIGSVHLWLAEAINA LQDNKDTLTAKVIQGCGNPKVNPQGPGPEEKRRRGKLALQEKPPSGTLQKLVPEAKAQLRDAQD FWISLPGMLCSEKLAMSSASDDRCWNGVAKGRYLPEVMGDGLANQINNPEVEVDVTKPDMTVRQ QIMQLKIMTNRLRSAYNGNDVDFQDASDDGSGSGSGDGCADDACGRRVSKKSSSSRTTLTHALP GLSEQEGQKTSAARCPQPCLCLLLLPVLALVLAASRPRWR hide sequence

RefSeq Acc Id:

ENSSSCP00000047245 ⟸ ENSSSCT00000060487

RefSeq Acc Id:

ENSSSCP00000017338 ⟸ ENSSSCT00000017819

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016364	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025071392	UniProtKB/TrEMBL
	ENSSSCG00035074768	UniProtKB/TrEMBL
	ENSSSCG00040058079	UniProtKB/TrEMBL
	ENSSSCG00045019500	UniProtKB/TrEMBL
	ENSSSCG00055029481	UniProtKB/TrEMBL
	ENSSSCG00060074215	UniProtKB/TrEMBL
	ENSSSCG00065076404	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000017819	ENTREZGENE
	ENSSSCT00000017819.3	UniProtKB/TrEMBL
	ENSSSCT00000060487	ENTREZGENE
	ENSSSCT00000060487.3	UniProtKB/TrEMBL
	ENSSSCT00025098079.1	UniProtKB/TrEMBL
	ENSSSCT00025098236.1	UniProtKB/TrEMBL
	ENSSSCT00035101603.1	UniProtKB/TrEMBL
	ENSSSCT00040078789.1	UniProtKB/TrEMBL
	ENSSSCT00040078945.1	UniProtKB/TrEMBL
	ENSSSCT00045033225.1	UniProtKB/TrEMBL
	ENSSSCT00055058553.1	UniProtKB/TrEMBL
	ENSSSCT00060101489.1	UniProtKB/TrEMBL
	ENSSSCT00060101577.1	UniProtKB/TrEMBL
	ENSSSCT00065105527.1	UniProtKB/TrEMBL
InterPro	Glypican	UniProtKB/TrEMBL
	Glypican_CS	UniProtKB/TrEMBL
KEGG Report	ssc:100525965	UniProtKB/TrEMBL
NCBI Gene	GPC1	ENTREZGENE
PANTHER	PTHR10822	UniProtKB/TrEMBL
	PTHR10822:SF8	UniProtKB/TrEMBL
Pfam	Glypican	UniProtKB/TrEMBL
PROSITE	GLYPICAN	UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
UniProt	A0A287ATH4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1F7W9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1KGL8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1WUM4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D2CI14	ENTREZGENE, UniProtKB/TrEMBL
	F1SIQ5	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:96329	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)