KLHDC8B (kelch domain containing 8B) - Rat Genome Database
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Gene: KLHDC8B (kelch domain containing 8B) Sus scrofa
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Symbol: KLHDC8B
Name: kelch domain containing 8B
RGD ID: 14122971
Description: INVOLVED IN DNA recombination (inferred); meiotic DNA double-strand break formation (inferred); mitotic cytokinetic process (inferred); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2P (ortholog); Hodgkin's lymphoma (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: kelch domain-containing protein 8B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,775,694 - 31,780,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,775,339 - 31,780,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,005,885 - 35,011,029 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Comparative Map Data
KLHDC8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,775,694 - 31,780,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,775,339 - 31,780,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,005,885 - 35,011,029 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHDC8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,171,598 - 49,176,486 (+)EnsemblGRCh38hg38GRCh38
GRCh38349,171,120 - 49,176,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,209,031 - 49,213,919 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,184,072 - 49,188,923 (+)NCBINCBI36hg18NCBI36
Celera349,166,287 - 49,171,188 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,266,977 - 49,271,878 (+)NCBIHuRef
CHM1_1349,161,789 - 49,166,690 (+)NCBICHM1_1
Klhdc8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,324,834 - 108,338,780 (-)NCBIGRCm39mm39
GRCm39 Ensembl9108,324,835 - 108,338,780 (-)Ensembl
GRCm389108,447,635 - 108,461,581 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,447,636 - 108,461,581 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,349,970 - 108,363,912 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,305,742 - 108,319,684 (-)NCBImm8
Celera9108,056,827 - 108,070,762 (-)NCBICelera
Cytogenetic Map9F2NCBI
Klhdc8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28109,141,594 - 109,146,584 (-)NCBI
Rnor_6.0 Ensembl8117,231,769 - 117,237,229 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08117,232,047 - 117,236,792 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,576,621 - 116,581,366 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,442,391 - 108,447,071 (-)NCBICelera
Cytogenetic Map8q32NCBI
Klhdc8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,158,162 - 1,163,305 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,158,888 - 1,162,710 (+)NCBIChiLan1.0ChiLan1.0
KLHDC8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,173,894 - 50,179,759 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,174,393 - 50,179,759 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,094,203 - 49,099,818 (+)NCBIMhudiblu_PPA_v0panPan3
KLHDC8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2040,023,411 - 40,026,552 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12040,012,797 - 40,027,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Klhdc8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936529863,052 - 872,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHDC8B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,573,720 - 10,578,629 (+)NCBI
ChlSab1.1 Ensembl2210,574,769 - 10,578,674 (+)Ensembl
Klhdc8b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,182,881 - 3,187,714 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 2
Low 8 4 1 5 2 21 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000055837   ⟹   ENSSSCP00000042031
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1331,775,694 - 31,780,484 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000063236   ⟹   ENSSSCP00000045493
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1331,775,718 - 31,780,481 (+)Ensembl
RefSeq Acc Id: XM_003132206   ⟹   XP_003132254
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11331,775,601 - 31,780,483 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005669537   ⟹   XP_005669594
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11331,775,817 - 31,780,483 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013981665   ⟹   XP_013837119
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11331,775,339 - 31,780,483 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013981666   ⟹   XP_013837120
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11331,775,598 - 31,780,483 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003132254 (Get FASTA)   NCBI Sequence Viewer  
  XP_005669594 (Get FASTA)   NCBI Sequence Viewer  
  XP_013837119 (Get FASTA)   NCBI Sequence Viewer  
  XP_013837120 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013837119   ⟸   XM_013981665
- Peptide Label: isoform X1
- UniProtKB: F1SPT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013837120   ⟸   XM_013981666
- Peptide Label: isoform X2
- UniProtKB: A0A287AN59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003132254   ⟸   XM_003132206
- Peptide Label: isoform X1
- UniProtKB: F1SPT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669594   ⟸   XM_005669537
- Peptide Label: isoform X1
- UniProtKB: F1SPT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000042031   ⟸   ENSSSCT00000055837
RefSeq Acc Id: ENSSSCP00000045493   ⟸   ENSSSCT00000063236


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011376 UniProtKB/TrEMBL
  ENSSSCG00000011379 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070004119 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012132 UniProtKB/TrEMBL
  ENSSSCP00000042031 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000045493 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070006353 UniProtKB/TrEMBL
  ENSSSCP00070006363 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012457 UniProtKB/TrEMBL
  ENSSSCT00000055837 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000063236 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070007730 UniProtKB/TrEMBL
  ENSSSCT00070007740 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.80 UniProtKB/TrEMBL
InterPro Gal_Oxase/kelch_b-propeller UniProtKB/TrEMBL
  IHO1 UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
KEGG Report ssc:100510980 UniProtKB/TrEMBL
NCBI Gene KLHDC8B ENTREZGENE
PANTHER PTHR35662 UniProtKB/TrEMBL
Pfam IHO1 UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
SMART Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF50965 UniProtKB/TrEMBL
UniProt A0A287ADZ4_PIG UniProtKB/TrEMBL
  A0A287AN59 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1STV4_PIG UniProtKB/TrEMBL
  A0A4X1SVK8_PIG UniProtKB/TrEMBL
  F1SPT3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89509 ENTREZGENE