SYNJ2BP (synaptojanin 2 binding protein)

Gene: SYNJ2BP (synaptojanin 2 binding protein) Sus scrofa

Analyze

Symbol:

SYNJ2BP

Name:

synaptojanin 2 binding protein

RGD ID:

14118608

Description:

ENCODES a protein that exhibits type II activin receptor binding (ortholog); INVOLVED IN intracellular distribution of mitochondria (ortholog); negative regulation of activin receptor signaling pathway (ortholog); positive regulation of activin receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cell surface (ortholog); mitochondrial outer membrane (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

synaptojanin-2-binding protein

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	93,906,182 - 93,974,444 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	93,906,182 - 93,974,336 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	100,228,872 - 100,248,552 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion (IEA)

chemical synaptic transmission (IEA)

establishment or maintenance of epithelial cell apical/basal polarity (IEA)

intracellular distribution of mitochondria (ISO)

negative regulation of activin receptor signaling pathway (ISO)

negative regulation of angiogenesis (IEA)

negative regulation of endothelial cell migration (IEA)

negative regulation of endothelial cell proliferation (IEA)

negative regulation of ERK1 and ERK2 cascade (IEA)

negative regulation of sprouting angiogenesis (IEA)

positive regulation of activin receptor signaling pathway (ISO)

positive regulation of protein localization to cell surface (ISO)

positive regulation of receptor internalization (ISO)

protein targeting (ISO)

receptor clustering (IEA)

receptor localization to synapse (IEA)

regulation of endocytosis (ISO)

regulation of Notch signaling pathway (IEA)

regulation of receptor internalization (ISO)

Rho protein signal transduction (ISO)

Cellular Component

basolateral plasma membrane (IEA)

cell surface (ISO)

membrane (IEA)

mitochondrial outer membrane (IEA,ISO)

mitochondrion (IEA)

neuromuscular junction (IEA)

neuron projection (IEA)

postsynaptic density membrane (IEA)

Molecular Function

protein binding (ISO)

type II activin receptor binding (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:15679890	PMID:22301074

Genomics

Comparative Map Data

SYNJ2BP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	93,906,182 - 93,974,444 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	93,906,182 - 93,974,336 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	100,228,872 - 100,248,552 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SYNJ2BP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	70,366,499 - 70,417,090 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	70,366,499 - 70,417,090 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	70,833,216 - 70,883,807 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	69,902,966 - 69,953,560 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	69,908,626 - 69,953,515	NCBI
Celera	14	50,897,314 - 50,948,137 (-)	NCBI		Celera
Cytogenetic Map	14	q24.2	NCBI
HuRef	14	51,001,739 - 51,052,566 (-)	NCBI		HuRef
CHM1_1	14	70,771,326 - 70,821,956 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	64,572,381 - 64,623,200 (-)	NCBI		T2T-CHM13v2.0

Synj2bp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	81,538,968 - 81,579,685 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	81,544,715 - 81,579,685 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	81,492,194 - 81,532,911 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	81,497,941 - 81,532,911 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	82,593,181 - 82,633,894 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	82,416,789 - 82,451,755 (-)	NCBI		MGSCv36	mm8
Celera	12	82,957,743 - 82,999,110 (-)	NCBI		Celera
Cytogenetic Map	12	D1	NCBI
cM Map	12	37.73	NCBI

Synj2bp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	106,920,970 - 106,958,653 (-)	NCBI		GRCr8
mRatBN7.2	6	101,189,714 - 101,227,400 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	101,189,714 - 101,227,406 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	101,344,901 - 101,382,579 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	101,644,086 - 101,681,768 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	101,016,608 - 101,054,310 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	105,224,166 - 105,261,549 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	105,224,166 - 105,261,549 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	113,370,333 - 113,407,716 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	105,352,102 - 105,389,779 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	105,356,721 - 105,393,256 (-)	NCBI
Celera	6	99,029,620 - 99,067,302 (-)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

Synj2bp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	80,766 - 121,980 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955466	80,766 - 127,383 (+)	NCBI	ChiLan1.0	ChiLan1.0

SYNJ2BP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	71,489,316 - 71,539,862 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	70,705,829 - 70,756,314 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	50,958,861 - 51,009,395 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	69,829,082 - 69,879,537 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	69,835,548 - 69,879,537 (-)	Ensembl	panpan1.1		panPan2

SYNJ2BP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	44,044,526 - 44,079,002 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	44,044,526 - 44,079,002 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	43,727,903 - 43,762,384 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	44,267,979 - 44,302,474 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	44,263,840 - 44,302,537 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	43,882,482 - 43,916,952 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	43,955,881 - 43,990,355 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	44,316,315 - 44,350,794 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101967553
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	60,681,189 - 60,745,379 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	13,482,975 - 13,510,693 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936495	13,444,726 - 13,471,914 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	13,446,325 - 13,510,495 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC103229268
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	47,612,405 - 47,658,378 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	47,612,975 - 47,629,109 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	35,827,634 - 35,873,728 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Synj2bp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	30,726,177 - 30,775,873 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	30,726,204 - 30,775,166 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SYNJ2BP
825 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	9	4	3	4	2	14	2	3
Low	1			1		9			3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001244991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021098201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK230580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK234980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK398903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY610174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU695063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01114139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000024697 ⟹ ENSSSCP00000020070

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	93,906,182 - 93,929,189 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000079959 ⟹ ENSSSCP00000066045

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	93,906,182 - 93,974,444 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000082979 ⟹ ENSSSCP00000072285

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	93,906,182 - 93,974,444 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000085468 ⟹ ENSSSCP00000060113

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	93,909,825 - 93,974,199 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000100325 ⟹ ENSSSCP00000075075

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	93,906,182 - 93,949,513 (-)	Ensembl

RefSeq Acc Id:

NM_001244991 ⟹ NP_001231920

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	93,909,181 - 93,974,336 (-)	NCBI

Sequence:

show sequence

AAAACTGAAAGTGCTGGGCTTCTGGCGCTAGACGCCAGGCCCCCCGGCGGATTTACATCTCCCC
CGTCACGAGCTGTTGCTGCTTCAAGTTGGGAAGCCAGACAAACAGTAAAATATGAACGGAAGAG
TGGATTATTTGGTTACTGAGGAAGAAATCAGTCTCACCAGAGGACCCTCAGGTCTGGGCTTCAA
CATCGTCGGTGGGACAGATCAGCAGTATGTCTCCAATGACAGTGGCATCTTCGTCAGCCGCATC
AAAGAGAATGGGGCTGCAGCCCTGGATGGGCGGCTCCAGGAGGGTGATAAGATCCTCTCGGTAA
ATGGCCAGGACCTAAAGAACCTGCTGCACCAGGATGCTGTAGACCTCTTTCGTAATGCAGGCTA
CACTGTGTCCCTGAGAGTGCAGCACAGGTCACAGGTGCAGAATGGGCCTGTGGGACATCAAGGT
GATGGGGAACCAAGTGGTATTCCCATAACTGTGGTGCTGGTGCCAGTGTTTGCCCTCATCATGG
TAGCAGCCTGGGCCTTCATGAGATACCGCCATCAACCTTGAAAAGCTCGCTTTCTTCCAGTGCT
CCCAAAGAAGAACACACATCCCTTTCTCTGACCTTCCTCCCCTGCCGTTCTCCCATAACTTTCC
CTTCCCCACATGGCCAACTCATGATTTAAAGAGACTGTTACCCAACCAGAACCTTGCTGTTTGA
AATCTTTGGTGGGAGAGTAAAGGCATTGTTTGAAGGAAAACTGAAGAAAGGACTTGCTTGGAAC
AAATGAAGAGTTATTTATGTTAGTAGGACCGCCAGAAGTTCAGCTATAACCCAAAGAGGAAAAG
GCCCAGTCTTCTCATCACCATGGGTGATTCTTTCTTTTCTTAGCTGGCATGTGTCAAAGGCCAG
CCATAAGAGAAAGTAAGGATTTTTCTTTTCAATAATCTTCCTTGGGAAGTTTCTGTGGCCTTTA
TTTAATTTCTAAGTACCTACTTGGGTGCCTACTTTGTATCAAATGAAGGCAAATGGGAAGAGCA
TTTCTATTTTTTTTTCAAAAGCAAATATATATAAATACATATGCATATATGATCATATAATAGT
AATGCCTTATGGAGAATTAAAGAGGTGGAAAGCAGCTCTGGTCCCTGGGCTTCCAACGTGGGTT
AAAAGATAATCTTAATTGAAGAATTCAATACGTAAAGGGAGTGAGAGAACAAGCCTTAAAAGAG
ACTGCCCAATCTGGATCATTTAAAGAAAGCAAACAGAAGCAACTAATTAAAACTCTTGGAATGA
TATTTCTTCTCCTAATGATAATTTTGGTGAAGTTGAGGTAAAATGCCATAATCCAGCTTTGCAC
AAGTCAATCTGTTTAAAAAACTTGGGAGATGTAGAGATAAATGTTACTAGTCTCTAGGCTACCC
TAGTGGCTGTTTTGGTACCTCACAGTCTGTTAAAGGATCAGCTGGAATGATTGTGGTGAGAGCT
ATGGCCAAACCAACCCAGTGAACGAACTCTAAGAAGAAACAGAATAGTGTCTCCAAGATGGCAC
CTCAGGCTATCTATCAGTCTTTCCTCTTTCTGTTAACAGGTAAAATCTAAGAGAAGGGACTGCT
GCTCCCCAGCGGGATGGGTATGAAATCAGCGCTGCTTCCATTCAATTAAGTTACAAGCGTTTGG
ATTGCTAATTTTTTTGGAAAGGCACTAAACACTGGTTGTGGCTTTTAATGAAGAAACCATTTTT
ACAGGGAAAGGGACGGAGCTTTGTTTGTTTTAGGGGTAGGGAAGTTTGGTGGCTGTTTGATGGG
AAAAGGTTATGGATGAATGGATGTTAGAGAATATCAAGAATGTTAATGAGGTGGGAACCCTCCT
GCTCATGGGGTTCTGAAGGTTGGTTTTAAAGCACTAAGGAAAGCTGAACCAAGGCTAGTTTTCT
GGCTTTAAGAAAATCATTTCCAGGAGTTCCCGTTGTGGCCTAGCGGTTAACAAATCCGACTAGG
AACCATGAGGTTGCGGGTTCGATCCCTGGCCCCGCTCAGTGCGTTGACGATCTGGCGTTGCCAT
GAGCTGTGGTGTAGGTTGCAGACATGGCTCGGATCCCGCATTGCTGTGGCTCTGGTGTAGGCCG
GTGGCTACAGCTCCGATTAGACCCCTAGCCTGGGAATCTTCGTATGCCACAGGAGCAGCCCTAG
AAAAGGCAAAAAGACAAAAAGACAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_021098201 ⟹ XP_020953860

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	93,906,182 - 93,928,857 (-)	NCBI

Sequence:

show sequence

AGGTCTGGGCTTCAACATCGTCGGTGGGACAGATCAGCAGTATGTCTCCAATGACAGTGGCATC
TTCGTCAGCCGCATCAAAGAGAATGGGGCTGCAGCCCTGGATGGGCGGCTCCAGGAGGGTGATA
AGATCCTCTCGTCAAATACTGGTCTTGACCCACTGGATTGACTTCACTATCTTCTATAATGGGT
CAGCAGACCTATATTTGAAAAATCACTACTCCAGTAAATGGAAAATCACTGATGAAATCTTTGG
ATGCATAGACTGTGGATTAAGTAGGGTAAATGGCCAGGACCTAAAGAACCTGCTGCACCAGGAT
GCTGTAGACCTCTTTCGTAATGCAGGCTACACTGTGTCCCTGAGAGTGCAGCACAGGTCACAGG
TGCAGAATGGGCCTGTGGGACATCAAGGTGATGGGGAACCAAGTGGTATTCCCATAACTGTGGT
GCTGGTGCCAGTGTTTGCCCTCATCATGGTAGCAGCCTGGGCCTTCATGAGATACCGCCATCAA
CCTTGAAAAGCTCGCTTTCTTCCAGTGCTCCCAAAGAAGAACACACATCCCTTTCTCTGACCTT
CCTCCCCTGCCGTTCTCCCATAACTTTCCCTTCCCCACATGGCCAACTCATGATTTAAAGAGAC
TGTTACCCAACCAGAACCTTGCTGTTTGAAATCTTTGGTGGGAGAGTAAAGGCATTGTTTGAAG
GAAAACTGAAGAAAGGACTTGCTTGGAACAAATGAAGAGTTATTTATGTTAGTAGGACCGCCAG
AAGTTCAGCTATAACCCAAAGAGGAAAAGGCCCAGTCTTCTCATCACCATGGGTGATTCTTTCT
TTTCTTAGCTGGCATGTGTCAAAGGCCAGCCATAAGAGAAAGTAAGGATTTTTCTTTTCAATAA
TCTTCCTTGGGAAGTTTCTGTGGCCTTTATTTAATTTCTAAGTACCTACTTGGGTGCCTACTTT
GTATCAAATGAAGGCAAATGAGAAGAGCATTTCTATTTTTTTTTCAAAAGCAAATATATATAAA
TACATATGCATATATGATCATATAATAGTAATGCCTTATGGAGAATTAAAGAGGTGGAAAGCAG
CTCTGGTCCCTGGGCTTCCAACGTGGGTTAAAAGATAATCTTAATTGAAGAATTCAATACGTAA
AGGGAGTGAGAGAACAAGCCTTAAAAGAGACTGCCCAATCTGGATCATTTAAAGAAAGCAAACA
GAAGCAACTAATTAAAACTCTTGGAATGATATTTCTTCTCCTAATGATAATTTTGGTGAAGTTG
AGGTAAAATGCCATAATCCAGCTTTGCACAAGTCAATCTGTTTAAAAAACTTGGGAGATGTAAA
GATAAATGTTACTAGTCTCTAGGCTACCCTAGTGGCTGTTTTGGTACCTCACAGTCTGTTAAAG
GATCAGCTGGAATGATTGTGGTGAGAGCTATGGCCAAACCAACCCAGTGAAAGAACTCTAAGAA
GAAACAGAATAGTGTCTCCAAGATGGCACCTCAGGCTATCTATCAGTCTTTCCTTTTTCTGTTA
ACAGGTAAAATCTAAGAGAAGGGACTGCTGCTCCCCAGCGGGATGGGTATGAAATCAGCGCTGC
TTCCATTCAATTAAGTTACAAGCGTTTGGATTGCTAATTTTTTTGGAAAGGCACTAAACACTGG
TTGTGGCTTTTAATGAAGAAACCATTTTACAGGGAAAGGGACGGAGCTTTGTTTGTTTTAGGGG
TAGGGAAGTTTGGTGGCTGTTTGATGGGAAAAGGTTATGGATGAATGGATGTTAGAGAATATCA
AGAATGTTAATGAGGTGGGAACCCTCCTGCTCATGGGGTTCTGAAGGTTGGTTTTAAAGCACTA
AGGAAAGCTGAACCAAGGCTAGTTTTCTGGCTTTAAGAAAATCATTTCCAGGAGTTCCCGTTGT
GGCCTAGCGGTTAACAAATCCGACTAGGAACCATGAGGTTGCGGGTTCGATCCCTGGCCCCGCT
CAGTGCGTTGACGATCTGGCGTTGCCATGAGCTGTGGTGTAGGTTGCAGACATGGCTCGGATCC
CGCATTGCTGTGGCTCTGGTGTAGGCCGGTGGCTACAGCTCCGATTAGACCCCTAGCCTGGGAA
TCTTCGTATGCCACAGGAGCAGCCCTAGAAAAGGCAAAAAGACAAAAAGACAAAAAAAAAAAAA
AAAAAAAAAAAAGAAAAAAGAAAAAGAAAGAAAATCATTTCCATCCTCTAAATACACTGATCAG
ACTATAGGCTTTGTATAATCTTGGTATCGAGAGTTTGAAGACTTTCCCTCAGGCAGTCAGTTGT
GTGCAATTTTTAGCATGGTAAGAATTTTACACATGTTGATTGGACCTCAGCTTTGTTAAGACTT
AATACAAAGAAGCAAAATACATAGCCTCCATCTCAAAGAGGGTTGTGTTTGTTTGTTTTGTTTT
GTTTTATGGTTCCAGTTGGGAAGAGAACCCTTATACATCTAAAATAAGATAATATAGGATTACC
TGCACAGGCAGGGCAATGTAAGTTGGTGTGAAATTTATATTGCACATGGCAGAATGGAGCAGTT
ACTAAGAATGGAGGCACTTGAGAAAGTTCCACAGAGGAAGGGAACGAGTTAAGGACCCTTGAGG
AGCTCACCATCTAATTAACAGCATCCACGTATAGATGAGAAGTTAAGATAATATCATCAGGTTA
AGTAATAGTTGAGAACAATAATGAAAAGAAACGGTACTATTCAGAATATGATGCAGTGACAAAA
ACAAAAGACGTGCAGGCACATTTTTAAGAATTCAGAAAAGGAAAGCTGTCATATGGTGGCATCA
GGCCATAGTGGAAAGGGAAGTCTTTAAAAAATAAAAACCCCAGTAAGGGCTTGCCTCTGGGTCC
CCTATTGGTATAAGAAGAAATTTGCTTTAAACACTCATATTAGGATTTCTGCCTTCAGACCCTC
TATTGGTTCAATACCTCTGAGACTCACTTAGATAACTGCCTTCATAGAGTCCACAAAGAAACCC
TGACAGTGTTCCAGTTCTCACCTCAACCAGCCCACTGTGGAGGCCCAACCTCTAGTGCCCTCCC
TGTATCTGAAGGAATGTCCATCAGCGTCTATAATGGGCCTGCTTCTCTTCCCCTCAGGGTTTCA
GCATTAACTCCTGAGAGGGCCTTGACACACACAAAATGAAGCACATGGCAGGCAGGAAGGAAAG
CTCTTTGGTTTTTTGTTTGTTGTTAGATGTAAATAAAAACACCCATGCCAGCTCATCGTTGGTA
GATGGGTTTTTTTGCTTTGGTTGATAATTGGGATTCCGATGAACTTTAGTAAATTTAGGTTTTT
TCCTCTGGAATTAAAGCATTTGAAGGTCAGTATATTCATGGTTTAGACATTTTGCTACTGCAAT
TATATTCTTATTTCTGATTCTCTGGAGAGCTAAATTACTGTCATAGATGGAGTATTGGTGTCCA
TTGTAGGTCGTCAAAAGAATTCATGCTCTTTATACTTTGAATCTAATATTTCTGGCACTTTATC
AATTGTATCTAAAATTCCTCCCACCTAAATTACTATGTTCAAAGTTTTAAAACATGAATGAAAA
TATTTGTATGACCATATACTTGAAAGACTTCTCAGTATTTATCATCCAGTATCATTTCTAGTAA
GACTAATTGTTTGCTTCAGTTATCTCTGTTTTCTTTTCCTGCCAAGTGTTAAGCAGTGCTGTTG
ATGTAACTTAATCACACCATCTAGCCATGTGTAATGGAAAAAGGAAATTAATACATGTGACTGC
ATTCTTAGCCATGGACTGAACTAAACCTTGGTTGGTAACACTGTGTTCATGCCTGAGGTCTAAG
TATTGTTAAAAAGACACTAAGGAAAAGAGAATAAATTGCATTCTTAGCCATGGACTGAACTAAA
CCTTGGTTGGTAACACTGTGTTCATGTCTGAGGTCTAAGTATTGTTAAGAAGACACTAAGGAAA
AGAGAATAAATTGCTTTCCTAAGATTACATAGGTGGTAATAATAGAATCAGGATTTAAACTCAG
GAGTTCAGGTGCCACCACCTATAATAGTTTCTCATTGGCTGTGGTTCTCAAAGTGAGGTCACTG
GACAAAGTGAGGTTACCTGGGAACTTGTTAGCAAAGCAAACTCTTGGGCTTCAGCCTCGACTTA
CTGAATCAGAAATTGTGTAAGGCACCCAGCAATCTGTTTTAATAATCCCTCCAGGTGACAGATA
CTAACGTTTGAGAATCACTGCTCGATGCCAATAGTCACCTTTCTCTCAGGTTAGAATCACTGGA
GGAACTTATAAAAATCCTGATGCCCAGGCTGCACCGAGACCAATTAATAGAATCTCTGGGTGTG
GGACTCGGCAGCGGTACCACAGAGTTCACCGGGTGATTCCAGTGTGCAATGTCAGACAAAAATG
CTCTCTGCCATTTACACCGAGGCATGCTTCAAATGATTAAACCACCTATAGGCATCACTCCAGC
CAAAAATGAGAATTTCACTTGGGCCTTTTCAGAGCCTCACCTCTCATTAGCTTCTACCTCACGT
AGAGATGTGGAATAAGAAGTAGCATTCTTTGGCTTCTGATTTGCTAAGGACTGACCAACTTCCA
GCAAAACGTATTAGTGGAGCATGTCAGTTTGTACATCTATTGAATGAAAACCAACTTTAGAGCA
TTGGAGCTAAAAGCTTCTGAGTTGGATCTATCTTAGAGATGAGAAAAATCAAGGTTCAGGAGAC
GTAAACTCACTTAACCCAGATCAAAGACATTGTCGCAGAGGTAGGTGCCCTTTCTGTTTCTCAT
ATATGTCTTGAATGTATCCACTACATGAACATAGACAAAACTATCCTTTTTATCTCAGTCCGCT
TCCAGGATCTTCTCTCTTTGGGCCTTAAATAAAGACCAGAAGAACTGATTGACAGCTGAAGGGT
ATTGCAAGTATCATGCAAAACTGAGAGATTACACAGAATAATCTGAGGAAGACCTAGTATTCAG
TCAGATGAGTTCTCATGAAGACAAATTCCAGTAGTTCGAATGGAGAGAAGTATGTTTTTTTTTT
TTTGACGTTGGACATTGTTTTTGTTGTGTAAATAAGCAATTTATAAAAATGAAACAACCTCAGG
TTCTCATAAGGGGAAATAGAGTTCATGTAATTTCATGTGAAGCCAATAAAGCTTTTATTCAAAT
CTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001231920	(Get FASTA)	NCBI Sequence Viewer
	XP_020953860	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000020070.4
	ENSSSCP00000066045
	ENSSSCP00000066045.1
	ENSSSCP00000072285
	ENSSSCP00000072285.2
	ENSSSCP00000075075.1
	ENSSSCP00005045058.1
	ENSSSCP00005045062.1
	ENSSSCP00005045073.1
	ENSSSCP00005045080.1
	ENSSSCP00015040845.1
	ENSSSCP00015040876.1
	ENSSSCP00015040931.1
	ENSSSCP00025014320.1
	ENSSSCP00025014347.1
	ENSSSCP00025014379.1
	ENSSSCP00025014410.1
	ENSSSCP00030014922.1
	ENSSSCP00030014927.1
	ENSSSCP00030014932.1
	ENSSSCP00035014913.1
	ENSSSCP00035014915.1
	ENSSSCP00035014917.1
	ENSSSCP00035014920.1
	ENSSSCP00040019765.1
	ENSSSCP00040019775.1
	ENSSSCP00040019783.1
	ENSSSCP00040019796.1
	ENSSSCP00045019312.1
	ENSSSCP00045019333.1
	ENSSSCP00045019370.1
	ENSSSCP00045019405.1
	ENSSSCP00050014390.1
	ENSSSCP00050014393.1
	ENSSSCP00050014394.1
	ENSSSCP00050014399.1
	ENSSSCP00055046712.1
	ENSSSCP00055046724.1
	ENSSSCP00055046737.1
	ENSSSCP00055046755.1
	ENSSSCP00060044238.1
	ENSSSCP00060044243.1
	ENSSSCP00060044253.1
	ENSSSCP00060044267.1
	ENSSSCP00065041138.1
	ENSSSCP00065041142.1
	ENSSSCP00065041144.1
	ENSSSCP00065041148.1
	ENSSSCP00070022401.1
	ENSSSCP00070022408.1

RefSeq Acc Id:	XP_020953860 ⟸ XM_021098201
- Peptide Label:	isoform X1
- UniProtKB:	A0A4X1TY90 (UniProtKB/TrEMBL), A0A5G2R627 (UniProtKB/TrEMBL), A0A8D0M5Z3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSPMTVASSSAASKRMGLQPWMGGSRRVIRSSRQILVLTHWIDFTIFYNGSADLYLKNHYSSKW KITDEIFGCIDCGLSRVNGQDLKNLLHQDAVDLFRNAGYTVSLRVQHRSQVQNGPVGHQGDGEP SGIPITVVLVPVFALIMVAAWAFMRYRHQP hide sequence

RefSeq Acc Id:	NP_001231920 ⟸ NM_001244991
- UniProtKB:	A0A4X1U3K8 (UniProtKB/TrEMBL), A0A480N646 (UniProtKB/TrEMBL), A0A8D0PYS6 (UniProtKB/TrEMBL), A0A8D1KX09 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNGRVDYLVTEEEISLTRGPSGLGFNIVGGTDQQYVSNDSGIFVSRIKENGAAALDGRLQEGDK ILSVNGQDLKNLLHQDAVDLFRNAGYTVSLRVQHRSQVQNGPVGHQGDGEPSGIPITVVLVPVF ALIMVAAWAFMRYRHQP hide sequence

RefSeq Acc Id:

ENSSSCP00000020070 ⟸ ENSSSCT00000024697

RefSeq Acc Id:

ENSSSCP00000066045 ⟸ ENSSSCT00000079959

RefSeq Acc Id:

ENSSSCP00000060113 ⟸ ENSSSCT00000085468

RefSeq Acc Id:

ENSSSCP00000072285 ⟸ ENSSSCT00000082979

RefSeq Acc Id:

ENSSSCP00000075075 ⟸ ENSSSCT00000100325

Protein Domains

PDZ

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000026389	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005044764	UniProtKB/TrEMBL
	ENSSSCG00015073550	UniProtKB/TrEMBL
	ENSSSCG00025025453	UniProtKB/TrEMBL
	ENSSSCG00030023804	UniProtKB/TrEMBL
	ENSSSCG00035028290	UniProtKB/TrEMBL
	ENSSSCG00040035126	UniProtKB/TrEMBL
	ENSSSCG00045016429	UniProtKB/TrEMBL
	ENSSSCG00050025669	UniProtKB/TrEMBL
	ENSSSCG00055029402	UniProtKB/TrEMBL
	ENSSSCG00060074445	UniProtKB/TrEMBL
	ENSSSCG00065068499	UniProtKB/TrEMBL
	ENSSSCG00070013807	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000024697.4	UniProtKB/TrEMBL
	ENSSSCT00000079959	ENTREZGENE
	ENSSSCT00000079959.2	UniProtKB/TrEMBL
	ENSSSCT00000082979	ENTREZGENE
	ENSSSCT00000082979.2	UniProtKB/TrEMBL
	ENSSSCT00000100325.1	UniProtKB/TrEMBL
	ENSSSCT00005072130.1	UniProtKB/TrEMBL
	ENSSSCT00005072135.1	UniProtKB/TrEMBL
	ENSSSCT00005072149.1	UniProtKB/TrEMBL
	ENSSSCT00005072157.1	UniProtKB/TrEMBL
	ENSSSCT00015098931.1	UniProtKB/TrEMBL
	ENSSSCT00015098989.1	UniProtKB/TrEMBL
	ENSSSCT00015099091.1	UniProtKB/TrEMBL
	ENSSSCT00025034374.1	UniProtKB/TrEMBL
	ENSSSCT00025034436.1	UniProtKB/TrEMBL
	ENSSSCT00025034518.1	UniProtKB/TrEMBL
	ENSSSCT00025034600.1	UniProtKB/TrEMBL
	ENSSSCT00030033092.1	UniProtKB/TrEMBL
	ENSSSCT00030033102.1	UniProtKB/TrEMBL
	ENSSSCT00030033114.1	UniProtKB/TrEMBL
	ENSSSCT00035037413.1	UniProtKB/TrEMBL
	ENSSSCT00035037418.1	UniProtKB/TrEMBL
	ENSSSCT00035037421.1	UniProtKB/TrEMBL
	ENSSSCT00035037430.1	UniProtKB/TrEMBL
	ENSSSCT00040047209.1	UniProtKB/TrEMBL
	ENSSSCT00040047239.1	UniProtKB/TrEMBL
	ENSSSCT00040047262.1	UniProtKB/TrEMBL
	ENSSSCT00040047317.1	UniProtKB/TrEMBL
	ENSSSCT00045027919.1	UniProtKB/TrEMBL
	ENSSSCT00045027955.1	UniProtKB/TrEMBL
	ENSSSCT00045028007.1	UniProtKB/TrEMBL
	ENSSSCT00045028063.1	UniProtKB/TrEMBL
	ENSSSCT00050034564.1	UniProtKB/TrEMBL
	ENSSSCT00050034567.1	UniProtKB/TrEMBL
	ENSSSCT00050034570.1	UniProtKB/TrEMBL
	ENSSSCT00050034577.1	UniProtKB/TrEMBL
	ENSSSCT00055058375.1	UniProtKB/TrEMBL
	ENSSSCT00055058388.1	UniProtKB/TrEMBL
	ENSSSCT00055058402.1	UniProtKB/TrEMBL
	ENSSSCT00055058423.1	UniProtKB/TrEMBL
	ENSSSCT00060101796.1	UniProtKB/TrEMBL
	ENSSSCT00060101806.1	UniProtKB/TrEMBL
	ENSSSCT00060101818.1	UniProtKB/TrEMBL
	ENSSSCT00060101847.1	UniProtKB/TrEMBL
	ENSSSCT00065094032.1	UniProtKB/TrEMBL
	ENSSSCT00065094039.1	UniProtKB/TrEMBL
	ENSSSCT00065094042.1	UniProtKB/TrEMBL
	ENSSSCT00065094053.1	UniProtKB/TrEMBL
	ENSSSCT00070026943.1	UniProtKB/TrEMBL
	ENSSSCT00070026954.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.42.10	UniProtKB/TrEMBL
InterPro	PDZ	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100514718	UniProtKB/TrEMBL
NCBI Gene	SYNJ2BP	ENTREZGENE
PANTHER	DISCS LARGE	UniProtKB/TrEMBL
	DISKS LARGE HOMOLOG 2	UniProtKB/TrEMBL
Pfam	PDZ	UniProtKB/TrEMBL
PROSITE	PDZ	UniProtKB/TrEMBL
SMART	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50156	UniProtKB/TrEMBL
UniProt	A0A480N646	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1TY90	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1U3K8	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2R627	ENTREZGENE
	A0A8D0M5Z3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0PYS6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0RDC2_PIG	UniProtKB/TrEMBL
	A0A8D1KX09	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1WSB0_PIG	UniProtKB/TrEMBL
	A0A8W4F8D5_PIG	UniProtKB/TrEMBL
	F1S4A6_PIG	UniProtKB/TrEMBL
UniProt Secondary	A0A5G2R627	UniProtKB/TrEMBL
	A0A5G2RJY2	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar