MIR128-1 (microRNA mir-128-1) - Rat Genome Database

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Gene: MIR128-1 (microRNA mir-128-1) Sus scrofa
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Symbol: MIR128-1
Name: microRNA mir-128-1
RGD ID: 14117915
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: microRNA 128-1; MIR128; ssc-mir-128; ssc-mir-128-1
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,273,551 - 16,273,659 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,273,557 - 16,273,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21518,661,614 - 18,661,695 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:19196471   PMID:19917043   PMID:20180025   PMID:21312241   PMID:24499489   PMID:32772776  


Genomics

Comparative Map Data
MIR128-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,273,551 - 16,273,659 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,273,557 - 16,273,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21518,661,614 - 18,661,695 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIR128-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,665,397 - 135,665,478 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2135,665,397 - 135,665,478 (+)EnsemblGRCh38hg38GRCh38
GRCh372136,422,967 - 136,423,048 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,139,436 - 136,139,517 (+)NCBINCBI36hg18NCBI36
Celera2130,133,728 - 130,133,809 (+)NCBI
Cytogenetic Map2q21.3NCBI
HuRef2128,415,938 - 128,416,019 (+)NCBIHuRef
CHM1_12136,427,877 - 136,427,958 (+)NCBICHM1_1
T2T-CHM13v2.02136,105,929 - 136,106,010 (+)NCBI
Mir128-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,130,098 - 128,130,167 (+)NCBIGRCm39mm39
GRCm39 Ensembl1128,130,098 - 128,130,167 (+)Ensembl
GRCm381128,202,361 - 128,202,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,202,361 - 128,202,430 (+)EnsemblGRCm38mm10GRCm38
MGSCv371130,098,938 - 130,099,007 (+)NCBIGRCm37mm9NCBIm37
Celera1130,829,788 - 130,829,857 (+)NCBICelera
Cytogenetic Map1E3NCBI
Mir128-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21339,699,449 - 39,699,530 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1339,699,449 - 39,699,530 (+)Ensembl
Rnor_6.01344,916,534 - 44,916,615 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,916,534 - 44,916,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01350,001,706 - 50,001,787 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1340,073,464 - 40,073,545 (+)NCBICelera
Cytogenetic Map13q13NCBI
MIR128-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,435,956 - 38,436,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,679,708 - 38,679,763 (+)NCBI
ROS_Cfam_1.01939,881,919 - 39,881,974 (+)NCBI
UMICH_Zoey_3.11938,524,004 - 38,524,059 (+)NCBI
UNSW_CanFamBas_1.01938,687,099 - 38,687,154 (+)NCBI
UU_Cfam_GSD_1.01939,920,158 - 39,920,213 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system respiratory system
High
Medium 3
Low 5 1 3 2 1 15 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000021098
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1516,273,551 - 16,273,659 (-)Ensembl
RefSeq Acc Id: NR_038503
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11516,273,557 - 16,273,638 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000019503 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000021098 ENTREZGENE
miRBase MI0002451 ENTREZGENE
NCBI Gene MIR128-1 ENTREZGENE
RNAcentral URS000024A59E RNACentral
  URS00002D9CBA RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR128-1  microRNA mir-128-1    microRNA 128-1  Symbol and/or name change 5135510 APPROVED