NACC2 (NACC family member 2) - Rat Genome Database

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Gene: NACC2 (NACC family member 2) Sus scrofa
Analyze
Symbol: NACC2
Name: NACC family member 2
RGD ID: 14117532
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of cell population proliferation (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); autosomal dominant nocturnal frontal lobe epilepsy 5 (ortholog); FOUND IN chromatin (inferred); mitochondrion (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleus accumbens-associated protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position: No map positions available.


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
mitochondrion  (IEA)
nucleolus  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NACC2
(Sus scrofa - pig)		 No map positions available.
NACC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,006,537 - 136,095,289 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,006,537 - 136,095,289 (-)EnsemblGRCh38hg38GRCh38
GRCh379138,898,383 - 138,987,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,043,023 - 138,126,952 (-)NCBINCBI36Build 36hg18NCBI36
Build 349136,129,149 - 136,213,076NCBI
Celera9109,421,076 - 109,505,450 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,360,255 - 108,449,736 (-)NCBIHuRef
CHM1_19139,046,411 - 139,135,603 (-)NCBICHM1_1
T2T-CHM13v2.09148,234,719 - 148,324,242 (-)NCBIT2T-CHM13v2.0
Nacc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,945,547 - 26,012,823 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,945,547 - 26,013,232 (-)EnsemblGRCm39 Ensembl
GRCm38226,055,535 - 26,122,811 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,055,535 - 26,123,220 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,911,056 - 25,978,331 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,877,545 - 25,944,820 (-)NCBIMGSCv36mm8
Celera225,778,060 - 25,845,474 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.29NCBI
Nacc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,278,077 - 29,345,098 (-)NCBIGRCr8
mRatBN7.238,879,952 - 8,946,660 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,883,065 - 8,946,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,937,224 - 12,000,522 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,520,445 - 20,583,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,775,758 - 18,839,059 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.033,508,084 - 3,574,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,510,041 - 3,574,787 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.038,869,877 - 8,936,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,237,814 - 4,301,608 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,238,197 - 4,270,534 (-)NCBI
Celera33,705,814 - 3,769,610 (-)NCBICelera
Cytogenetic Map3p13NCBI
Nacc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,561,643 - 4,595,364 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,560,903 - 4,595,081 (+)NCBIChiLan1.0ChiLan1.0
NACC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,290,798 - 3,380,006 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan193,293,135 - 3,382,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,079,113 - 107,168,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,061,365 - 136,106,911 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,066,229 - 136,105,176 (-)Ensemblpanpan1.1panPan2
NACC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,323,613 - 49,393,017 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,363,280 - 49,389,508 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,578,087 - 48,645,665 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,204,275 - 50,271,886 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl950,204,294 - 50,271,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,984,754 - 49,047,941 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,279,041 - 49,346,663 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,362,790 - 49,394,295 (+)NCBIUU_Cfam_GSD_1.0
Nacc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947201,671,301 - 201,704,931 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,670,423 - 1,703,781 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,670,798 - 1,703,757 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NACC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1122,104,649 - 2,192,283 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl122,148,312 - 2,192,432 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,017,126 - 3,106,003 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nacc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,318,993 - 1,349,810 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,319,092 - 1,386,692 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3
Low 8 4 3 4 2 20 2 3 2
Below cutoff 2 1 1

Sequence


Protein Domains
BEN   BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000040967 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025055811 UniProtKB/TrEMBL
  ENSSSCG00030024450 UniProtKB/TrEMBL
  ENSSSCG00045008663 UniProtKB/TrEMBL
  ENSSSCG00055002703 UniProtKB/TrEMBL
  ENSSSCG00065015889 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000066051 ENTREZGENE
  ENSSSCT00000066051.3 UniProtKB/TrEMBL
  ENSSSCT00025076353.1 UniProtKB/TrEMBL
  ENSSSCT00030034069.1 UniProtKB/TrEMBL
  ENSSSCT00045014627.1 UniProtKB/TrEMBL
  ENSSSCT00055005166.1 UniProtKB/TrEMBL
  ENSSSCT00065021072.1 UniProtKB/TrEMBL
Gene3D-CATH BEN domain UniProtKB/TrEMBL
InterPro BEN_domain UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene NACC2 ENTREZGENE
PANTHER AGAP004733-PA UniProtKB/TrEMBL
  NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
Pfam BEN UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
PROSITE BEN UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
SMART BEN UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A287B5L3 ENTREZGENE, UniProtKB/TrEMBL
  A0A480JMR0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W4F8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90564 ENTREZGENE