CDC42SE1 (CDC42 small effector 1) - Rat Genome Database

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Gene: CDC42SE1 (CDC42 small effector 1) Sus scrofa
Analyze
Symbol: CDC42SE1
Name: CDC42 small effector 1
RGD ID: 14114723
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN phagocytosis (inferred); regulation of cell shape (inferred); regulation of Rho protein signal transduction (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cell junction (inferred); cytoskeleton (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDC42 small effector protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,164,024 - 98,180,576 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,171,937 - 98,180,577 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,424,892 - 107,433,555 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:30032202  


Genomics

Comparative Map Data
CDC42SE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,164,024 - 98,180,576 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,171,937 - 98,180,577 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,424,892 - 107,433,555 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42SE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,050,985 - 151,059,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,050,971 - 151,070,325 (-)EnsemblGRCh38hg38GRCh38
GRCh371151,023,461 - 151,032,098 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,290,071 - 149,298,749 (-)NCBINCBI36Build 36hg18NCBI36
Build 341147,836,532 - 147,845,123NCBI
Celera1124,138,756 - 124,147,427 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,400,859 - 122,409,533 (-)NCBIHuRef
CHM1_11152,418,769 - 152,427,442 (-)NCBICHM1_1
T2T-CHM13v2.01150,174,667 - 150,183,297 (-)NCBIT2T-CHM13v2.0
Cdc42se1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,135,735 - 95,143,735 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,136,043 - 95,143,720 (+)EnsemblGRCm39 Ensembl
GRCm38395,228,424 - 95,236,424 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,228,732 - 95,236,409 (+)EnsemblGRCm38mm10GRCm38
MGSCv37395,032,702 - 95,040,331 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,314,184 - 95,321,813 (+)NCBIMGSCv36mm8
Celera396,659,877 - 96,667,458 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Cdc42se1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,494,692 - 185,502,519 (+)NCBIGRCr8
mRatBN7.22182,805,691 - 182,813,520 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,804,925 - 182,814,028 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,471,040 - 190,478,847 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,266,564 - 188,274,359 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,103,533 - 183,111,340 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02196,402,837 - 196,410,664 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,402,837 - 196,410,659 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,899,668 - 215,907,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,138,391 - 190,146,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2175,339,341 - 175,347,166 (+)NCBICelera
Cytogenetic Map2q34NCBI
Cdc42se1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588423,091 - 429,917 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955588423,091 - 440,248 (-)NCBIChiLan1.0ChiLan1.0
CDC42SE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,773,658 - 98,782,649 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,528,046 - 98,535,153 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,400,094 - 126,408,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,047,765 - 130,056,447 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,047,765 - 130,056,447 (-)Ensemblpanpan1.1panPan2
CDC42SE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,138,497 - 60,146,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,140,632 - 60,155,099 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,584,496 - 59,589,871 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,154,355 - 61,162,174 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11759,985,803 - 59,991,178 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,070,704 - 60,076,079 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,798,258 - 60,803,633 (-)NCBIUU_Cfam_GSD_1.0
Cdc42se1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,238,782 - 22,242,417 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,268,195 - 1,276,361 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,268,202 - 1,276,485 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42SE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,633,187 - 12,636,838 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1641,319,304 - 41,319,540 (+)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl1641,319,304 - 41,319,540 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603812,216,613 - 12,225,513 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc42se1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,768,827 - 18,774,859 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,768,765 - 18,774,859 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDC42SE1
143 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 2 5 6 3 3
Low 2 2 1 2 17 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000053900   ⟹   ENSSSCP00000035057
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl498,164,024 - 98,180,576 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000098678   ⟹   ENSSSCP00000078163
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl498,172,452 - 98,180,570 (+)Ensembl
RefSeq Acc Id: NM_001190193   ⟹   NP_001177122
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1498,172,668 - 98,178,975 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005663461   ⟹   XP_005663518
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1498,172,409 - 98,180,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013997164   ⟹   XP_013852618
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1498,171,937 - 98,180,577 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021088571   ⟹   XP_020944230
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1498,172,423 - 98,180,577 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013852618   ⟸   XM_013997164
- Peptide Label: isoform X1
- UniProtKB: A0A4X1W1R4 (UniProtKB/TrEMBL),   A0A8D0MEY8 (UniProtKB/TrEMBL),   A0A8D1Q177 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005663518   ⟸   XM_005663461
- Peptide Label: isoform X2
- UniProtKB: A0A287BD30 (UniProtKB/TrEMBL),   A0A4X1W2X3 (UniProtKB/TrEMBL),   A0A8D1G4K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944230   ⟸   XM_021088571
- Peptide Label: isoform X2
- UniProtKB: A0A4X1W2X3 (UniProtKB/TrEMBL),   A0A287BD30 (UniProtKB/TrEMBL),   A0A8D1G4K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001177122   ⟸   NM_001190193
- UniProtKB: A0A287BD30 (UniProtKB/TrEMBL),   A0A4X1W2X3 (UniProtKB/TrEMBL),   A0A8D1G4K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000035057   ⟸   ENSSSCT00000053900
RefSeq Acc Id: ENSSSCP00000078163   ⟸   ENSSSCT00000098678
Protein Domains
CRIB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031881 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005013500 UniProtKB/TrEMBL
  ENSSSCG00015004693 UniProtKB/TrEMBL
  ENSSSCG00025051529 UniProtKB/TrEMBL
  ENSSSCG00030058573 UniProtKB/TrEMBL
  ENSSSCG00035061774 UniProtKB/TrEMBL
  ENSSSCG00040075685 UniProtKB/TrEMBL
  ENSSSCG00045021597 UniProtKB/TrEMBL
  ENSSSCG00050048347 UniProtKB/TrEMBL
  ENSSSCG00055008217 UniProtKB/TrEMBL
  ENSSSCG00060010958 UniProtKB/TrEMBL
  ENSSSCG00065060662 UniProtKB/TrEMBL
  ENSSSCG00070028081 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053900 ENTREZGENE
  ENSSSCT00000053900.2 UniProtKB/TrEMBL
  ENSSSCT00000098678.1 UniProtKB/TrEMBL
  ENSSSCT00005021051.1 UniProtKB/TrEMBL
  ENSSSCT00005021078.1 UniProtKB/TrEMBL
  ENSSSCT00005021090.1 UniProtKB/TrEMBL
  ENSSSCT00015006315.1 UniProtKB/TrEMBL
  ENSSSCT00015006318.1 UniProtKB/TrEMBL
  ENSSSCT00025070432.1 UniProtKB/TrEMBL
  ENSSSCT00025070504.1 UniProtKB/TrEMBL
  ENSSSCT00030081749.1 UniProtKB/TrEMBL
  ENSSSCT00030081773.1 UniProtKB/TrEMBL
  ENSSSCT00030081792.1 UniProtKB/TrEMBL
  ENSSSCT00030081812.1 UniProtKB/TrEMBL
  ENSSSCT00035082999.1 UniProtKB/TrEMBL
  ENSSSCT00035083001.1 UniProtKB/TrEMBL
  ENSSSCT00040105087.1 UniProtKB/TrEMBL
  ENSSSCT00040105089.1 UniProtKB/TrEMBL
  ENSSSCT00045036889.1 UniProtKB/TrEMBL
  ENSSSCT00050065853.1 UniProtKB/TrEMBL
  ENSSSCT00050065859.1 UniProtKB/TrEMBL
  ENSSSCT00055016007.1 UniProtKB/TrEMBL
  ENSSSCT00055016024.1 UniProtKB/TrEMBL
  ENSSSCT00060014287.1 UniProtKB/TrEMBL
  ENSSSCT00060014289.1 UniProtKB/TrEMBL
  ENSSSCT00065083082.1 UniProtKB/TrEMBL
  ENSSSCT00065083087.1 UniProtKB/TrEMBL
  ENSSSCT00070056345.1 UniProtKB/TrEMBL
  ENSSSCT00070056347.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.810.10 UniProtKB/TrEMBL
InterPro CRIB_dom UniProtKB/TrEMBL
  CRIB_dom_sf UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
KEGG Report ssc:100156313 UniProtKB/TrEMBL
NCBI Gene CDC42SE1 ENTREZGENE
PANTHER CDC42 SMALL EFFECTOR PROTEIN 1 UniProtKB/TrEMBL
  PTHR13502 UniProtKB/TrEMBL
PROSITE CRIB UniProtKB/TrEMBL
UniProt A0A287BD30 ENTREZGENE
  A0A4X1W1R4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W2X3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MEY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0UUK5_PIG UniProtKB/TrEMBL
  A0A8D0XK17_PIG UniProtKB/TrEMBL
  A0A8D1G4K1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Q177 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FIM1_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287BD30 UniProtKB/TrEMBL
VGNC ID VGNC:86460 ENTREZGENE