ASB14 (ankyrin repeat and SOCS box containing 14) - Rat Genome Database

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Gene: ASB14 (ankyrin repeat and SOCS box containing 14) Sus scrofa
Analyze
Symbol: ASB14
Name: ankyrin repeat and SOCS box containing 14
RGD ID: 14112124
Description: ENCODES a protein that exhibits transcription cis-regulatory region binding (inferred); INVOLVED IN intracellular signal transduction (inferred); positive regulation of transcription by RNA polymerase II (inferred); protein ubiquitination (inferred); ASSOCIATED WITH genetic disease (ortholog); maturity-onset diabetes of the young type 14 (ortholog); Pyruvate Dehydrogenase E1-Beta Deficiency (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankyrin repeat and SOCS box protein 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1339,123,650 - 39,146,914 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11339,121,461 - 39,147,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ASB14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1339,123,650 - 39,146,914 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11339,121,461 - 39,147,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ASB14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38357,268,342 - 57,292,685 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl357,268,342 - 57,292,685 (-)EnsemblGRCh38hg38GRCh38
GRCh37357,302,370 - 57,326,713 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36357,277,419 - 57,288,020 (-)NCBINCBI36Build 36hg18NCBI36
Build 34357,277,418 - 57,288,020NCBI
Celera357,267,953 - 57,292,330 (-)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef357,351,544 - 57,375,919 (-)NCBIHuRef
CHM1_1357,252,526 - 57,276,848 (-)NCBICHM1_1
T2T-CHM13v2.0357,308,608 - 57,332,970 (-)NCBIT2T-CHM13v2.0
Asb14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391426,616,547 - 26,638,393 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1426,616,514 - 26,637,215 (+)EnsemblGRCm39 Ensembl
GRCm381426,894,590 - 26,915,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1426,894,557 - 26,915,258 (+)EnsemblGRCm38mm10GRCm38
MGSCv371427,707,790 - 27,728,443 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361425,730,127 - 25,742,142 (+)NCBIMGSCv36mm8
Celera1423,133,157 - 23,154,948 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.09NCBI
Asb14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8162,102,303 - 2,131,379 (+)NCBIGRCr8
mRatBN7.2162,095,567 - 2,123,259 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl162,095,644 - 2,115,135 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx162,102,250 - 2,121,773 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0163,247,937 - 3,267,460 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,108,637 - 2,127,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0162,537,209 - 2,556,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl162,537,248 - 2,556,735 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0162,511,969 - 2,531,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4162,162,243 - 2,175,971 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera162,063,524 - 2,083,013 (+)NCBICelera
Cytogenetic Map16p16NCBI
Asb14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554307,020,823 - 7,038,057 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554307,014,091 - 7,038,751 (-)NCBIChiLan1.0ChiLan1.0
ASB14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2257,241,429 - 57,260,549 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1357,246,640 - 57,265,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0357,209,408 - 57,225,472 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1358,418,243 - 58,434,409 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl358,418,243 - 58,434,409 (-)Ensemblpanpan1.1panPan2
ASB14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12033,110,930 - 33,137,249 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2033,110,992 - 33,133,695 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2033,038,555 - 33,065,206 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02033,383,368 - 33,410,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2033,383,438 - 33,408,610 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12032,832,425 - 32,859,045 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02033,190,899 - 33,217,541 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02033,361,952 - 33,388,842 (+)NCBIUU_Cfam_GSD_1.0
Asb14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118174,478,515 - 174,494,626 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364737,610,783 - 7,632,249 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364737,616,912 - 7,633,100 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASB14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12218,595,768 - 18,613,583 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2218,596,107 - 18,612,536 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041148,257,866 - 148,274,769 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asb14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462482219,813 - 29,974 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ASB14
174 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 4 4 3 5 14 1 3 2
Below cutoff 5 9 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000063151   ⟹   ENSSSCP00000053251
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1339,123,650 - 39,146,914 (-)Ensembl
RefSeq Acc Id: XM_021068997   ⟹   XP_020924656
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,126,545 - 39,147,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068998   ⟹   XP_020924657
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,121,461 - 39,147,488 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068999   ⟹   XP_020924658
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,126,545 - 39,147,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069001   ⟹   XP_020924660
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,126,545 - 39,147,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069002   ⟹   XP_020924661
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,126,545 - 39,147,490 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069003   ⟹   XP_020924662
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11339,126,545 - 39,147,489 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020924657   ⟸   XM_021068998
- Peptide Label: isoform X1
- UniProtKB: A0A287BAX4 (UniProtKB/TrEMBL),   A0A4X1VJQ0 (UniProtKB/TrEMBL),   A0A8D1Q201 (UniProtKB/TrEMBL),   A0A8D1K1J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020924661   ⟸   XM_021069002
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020924662   ⟸   XM_021069003
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020924660   ⟸   XM_021069001
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020924658   ⟸   XM_021068999
- Peptide Label: isoform X1
- UniProtKB: A0A287BAX4 (UniProtKB/TrEMBL),   A0A4X1VJQ0 (UniProtKB/TrEMBL),   A0A8D1Q201 (UniProtKB/TrEMBL),   A0A8D1K1J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020924656   ⟸   XM_021068997
- Peptide Label: isoform X1
- UniProtKB: A0A287BAX4 (UniProtKB/TrEMBL),   A0A4X1VJQ0 (UniProtKB/TrEMBL),   A0A8D1Q201 (UniProtKB/TrEMBL),   A0A8D1K1J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000053251   ⟸   ENSSSCT00000063151
Protein Domains
SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005021599 UniProtKB/TrEMBL
  ENSSSCG00015067949 UniProtKB/TrEMBL
  ENSSSCG00025025417 UniProtKB/TrEMBL
  ENSSSCG00035072833 UniProtKB/TrEMBL
  ENSSSCG00040059932 UniProtKB/TrEMBL
  ENSSSCG00045027492 UniProtKB/TrEMBL
  ENSSSCG00050004982 UniProtKB/TrEMBL
  ENSSSCG00055009779 UniProtKB/TrEMBL
  ENSSSCG00060004040 UniProtKB/TrEMBL
  ENSSSCG00065016338 UniProtKB/TrEMBL
  ENSSSCG00070024923 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000063151 ENTREZGENE
  ENSSSCT00000063151.1 UniProtKB/TrEMBL
  ENSSSCT00005034086.1 UniProtKB/TrEMBL
  ENSSSCT00015091018.1 UniProtKB/TrEMBL
  ENSSSCT00025034313.1 UniProtKB/TrEMBL
  ENSSSCT00035098608.1 UniProtKB/TrEMBL
  ENSSSCT00040081487.1 UniProtKB/TrEMBL
  ENSSSCT00045046777.1 UniProtKB/TrEMBL
  ENSSSCT00050006843.1 UniProtKB/TrEMBL
  ENSSSCT00055019106.1 UniProtKB/TrEMBL
  ENSSSCT00060004999.1 UniProtKB/TrEMBL
  ENSSSCT00065021676.1 UniProtKB/TrEMBL
  ENSSSCT00070049796.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  SOCS box UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
NCBI Gene ASB14 ENTREZGENE
PANTHER ANK_REP_REGION DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  ANKYRIN REPEAT PROTEIN UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
UniProt A0A287BAX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VJQ0 ENTREZGENE
  A0A8D1K1J0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Q201 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1VJQ0 UniProtKB/TrEMBL
VGNC ID VGNC:85562 ENTREZGENE