FREM2 (FRAS1 related extracellular matrix 2) - Rat Genome Database

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Gene: FREM2 (FRAS1 related extracellular matrix 2) Sus scrofa
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Symbol: FREM2
Name: FRAS1 related extracellular matrix 2
RGD ID: 14102857
Description: INVOLVED IN embryonic digit morphogenesis (ortholog); eye development (ortholog); heart development (ortholog); ASSOCIATED WITH CAKUT (ortholog); Childhood Schizophrenia (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN basement membrane (inferred); integral component of membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: FRAS1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,959,865 - 14,154,246 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,775,267 - 14,116,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
FREM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,959,865 - 14,154,246 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,775,267 - 14,116,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FREM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1338,687,077 - 38,887,131 (+)EnsemblGRCh38hg38GRCh38
GRCh381338,687,041 - 38,887,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371339,261,214 - 39,461,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361338,159,173 - 38,359,268 (+)NCBINCBI36hg18NCBI36
Build 341338,255,292 - 38,358,072NCBI
Celera1320,314,868 - 20,515,290 (+)NCBI
Cytogenetic Map13q13.3NCBI
HuRef1320,059,603 - 20,259,887 (+)NCBIHuRef
CHM1_11339,228,938 - 39,428,968 (+)NCBICHM1_1
Frem2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39353,421,359 - 53,566,014 (-)NCBIGRCm39mm39
GRCm39 Ensembl353,421,359 - 53,564,776 (-)Ensembl
GRCm38353,513,938 - 53,658,593 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl353,513,938 - 53,657,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv37353,317,860 - 53,461,277 (-)NCBIGRCm37mm9NCBIm37
MGSCv36353,601,867 - 53,745,013 (-)NCBImm8
Celera353,238,829 - 53,381,524 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map325.24NCBI
Frem2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22137,602,784 - 137,740,785 (-)NCBI
Rnor_6.0 Ensembl2142,747,501 - 142,885,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
Frem2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554317,364,937 - 7,541,648 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554317,364,937 - 7,541,419 (-)NCBIChiLan1.0ChiLan1.0
FREM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11338,490,750 - 38,692,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1338,490,750 - 38,687,048 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01319,900,324 - 20,103,303 (+)NCBIMhudiblu_PPA_v0panPan3
FREM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1252,097,264 - 2,264,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl252,102,849 - 2,264,456 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha252,193,436 - 2,359,496 (-)NCBI
ROS_Cfam_1.0252,194,254 - 2,360,131 (-)NCBI
UMICH_Zoey_3.1252,095,553 - 2,261,726 (-)NCBI
UNSW_CanFamBas_1.0252,089,594 - 2,255,805 (-)NCBI
UU_Cfam_GSD_1.0252,159,315 - 2,325,419 (-)NCBI
Frem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945163,183,741 - 163,353,464 (-)NCBI
SpeTri2.0NW_0049365656,671,578 - 6,837,514 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FREM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1317,121,063 - 17,310,149 (+)NCBI
ChlSab1.1 Ensembl317,129,126 - 17,300,363 (+)Ensembl
Vero_WHO_p1.0NW_02366605726,957,763 - 27,140,436 (-)NCBI
Frem2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249201,683,342 - 1,908,602 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 3 2 1
Low 8 4 5 2 20 2 3
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010261   ⟹   ENSSSCP00000009994
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1113,959,865 - 14,154,246 (+)Ensembl
RefSeq Acc Id: XM_021065215   ⟹   XP_020920874
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11113,775,267 - 14,113,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065216   ⟹   XP_020920875
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11113,775,267 - 14,113,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065217   ⟹   XP_020920876
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11113,775,285 - 14,113,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021065218   ⟹   XP_020920877
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11113,775,267 - 14,116,377 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020920874 (Get FASTA)   NCBI Sequence Viewer  
  XP_020920875 (Get FASTA)   NCBI Sequence Viewer  
  XP_020920876 (Get FASTA)   NCBI Sequence Viewer  
  XP_020920877 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020920877   ⟸   XM_021065218
- Sequence:
RefSeq Acc Id: XP_020920875   ⟸   XM_021065216
- Sequence:
RefSeq Acc Id: XP_020920874   ⟸   XM_021065215
- Sequence:
RefSeq Acc Id: XP_020920876   ⟸   XM_021065217
- Sequence:
RefSeq Acc Id: ENSSSCP00000009994   ⟸   ENSSSCT00000010261
Protein Domains
Calx-beta


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009364 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000009994 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010261 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2030 UniProtKB/TrEMBL
InterPro CalX-like_sf UniProtKB/TrEMBL
  Calx_beta UniProtKB/TrEMBL
  CSPG_rpt UniProtKB/TrEMBL
NCBI Gene FREM2 ENTREZGENE
Pfam Calx-beta UniProtKB/TrEMBL
PROSITE CSPG UniProtKB/TrEMBL
SMART Calx_beta UniProtKB/TrEMBL
Superfamily-SCOP SSF141072 UniProtKB/TrEMBL
UniProt F1RS31_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88234 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 FREM2  FRAS1 related extracellular matrix 2    FRAS1 related extracellular matrix protein 2  Symbol and/or name change 5135510 APPROVED