SLC25A12 (solute carrier family 25 member 12) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SLC25A12 (solute carrier family 25 member 12) Sus scrofa
Analyze
Symbol: SLC25A12
Name: solute carrier family 25 member 12
RGD ID: 14101504
Description: ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); L-aspartate transmembrane transporter activity (inferred); INVOLVED IN glutamate biosynthetic process (ortholog); malate-aspartate shuttle (ortholog); negative regulation of glucose catabolic process to lactate via pyruvate (ortholog); PARTICIPATES IN argininosuccinic aciduria pathway; carbamoyl phosphate synthetase I deficiency pathway; citrullinemia pathway; ASSOCIATED WITH Asperger syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: calcium-binding mitochondrial carrier protein Aralar1; solute carrier family 25 (aspartate/glutamate carrier), member 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1577,895,935 - 78,098,383 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11577,895,935 - 78,021,930 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,284,119 - 87,308,544 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
SLC25A12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1577,895,935 - 78,098,383 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11577,895,935 - 78,021,930 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21587,284,119 - 87,308,544 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2171,783,405 - 171,999,859 (-)EnsemblGRCh38hg38GRCh38
GRCh382171,783,405 - 171,894,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372172,639,915 - 172,750,754 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh372172,639,915 - 172,750,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,349,126 - 172,458,979 (-)NCBINCBI36hg18NCBI36
Build 342172,466,387 - 172,576,240NCBI
Celera2166,256,502 - 166,367,904 (-)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2164,525,268 - 164,635,693 (-)NCBIHuRef
CHM1_12172,646,763 - 172,757,956 (-)NCBICHM1_1
Slc25a12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39271,104,614 - 71,198,125 (-)NCBIGRCm39mm39
GRCm38271,274,270 - 71,367,781 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,271,063 - 71,367,749 (-)EnsemblGRCm38mm10GRCm38
MGSCv37271,112,352 - 71,205,611 (-)NCBIGRCm37mm9NCBIm37
MGSCv36271,075,134 - 71,168,393 (-)NCBImm8
Celera272,934,243 - 73,030,549 (-)NCBICelera
Cytogenetic Map2C2NCBI
Slc25a12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2356,098,080 - 56,192,188 (-)NCBI
Rnor_6.0 Ensembl357,882,370 - 57,957,346 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0357,881,951 - 57,998,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0364,425,236 - 64,487,369 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0364,377,674 - 64,416,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4353,620,160 - 53,680,498NCBIRGSC3.4rn4RGSC3.4
Celera355,645,527 - 55,739,772 (-)NCBICelera
Cytogenetic Map3q22NCBI
Slc25a12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554493,093,603 - 3,186,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554493,093,603 - 3,182,513 (+)NCBIChiLan1.0ChiLan1.0
SLC25A12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B176,532,940 - 176,755,193 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,532,940 - 176,641,894 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B59,071,123 - 59,297,327 (-)NCBIMhudiblu_PPA_v0panPan3
SLC25A12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3616,185,649 - 16,483,016 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13616,185,011 - 16,391,080 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc25a12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365091,994,082 - 2,077,731 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11057,268,948 - 57,387,958 (-)NCBI
ChlSab1.1 Ensembl1057,265,550 - 57,387,910 (-)Ensembl
Slc25a12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247879,187,450 - 9,319,684 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 4 3 5 2 23 1 1 3
Low 5 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017366   ⟹   ENSSSCP00000016902
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,281 - 78,022,072 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000022813   ⟹   ENSSSCP00000020443
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,282 - 78,098,376 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000031044   ⟹   ENSSSCP00000019465
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,347 - 77,995,124 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041543   ⟹   ENSSSCP00000033543
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,333 - 78,098,383 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000070397   ⟹   ENSSSCP00000069856
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,895,935 - 77,995,103 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076758   ⟹   ENSSSCP00000061003
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,279 - 77,981,785 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000090247   ⟹   ENSSSCP00000066367
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,346 - 77,995,124 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091496   ⟹   ENSSSCP00000066301
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1577,896,279 - 77,994,201 (-)Ensembl
RefSeq Acc Id: XM_021075518   ⟹   XP_020931177
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11577,895,935 - 78,021,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075519   ⟹   XP_020931178
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11577,895,935 - 77,995,102 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075520   ⟹   XP_020931179
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11577,895,935 - 77,995,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075521   ⟹   XP_020931180
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11577,895,935 - 77,995,105 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075522   ⟹   XP_020931181
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11577,895,935 - 77,995,200 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020931177   ⟸   XM_021075518
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020931181   ⟸   XM_021075522
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020931179   ⟸   XM_021075520
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020931180   ⟸   XM_021075521
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020931178   ⟸   XM_021075519
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000066367   ⟸   ENSSSCT00000090247
RefSeq Acc Id: ENSSSCP00000033543   ⟸   ENSSSCT00000041543
RefSeq Acc Id: ENSSSCP00000069856   ⟸   ENSSSCT00000070397
RefSeq Acc Id: ENSSSCP00000019465   ⟸   ENSSSCT00000031044
RefSeq Acc Id: ENSSSCP00000016902   ⟸   ENSSSCT00000017366
RefSeq Acc Id: ENSSSCP00000066301   ⟸   ENSSSCT00000091496
RefSeq Acc Id: ENSSSCP00000061003   ⟸   ENSSSCT00000076758
RefSeq Acc Id: ENSSSCP00000020443   ⟸   ENSSSCT00000022813
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015949 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070023047 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000016902 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000019465 UniProtKB/TrEMBL
  ENSSSCP00000020443 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000033543 UniProtKB/TrEMBL
  ENSSSCP00000061003 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000066301 UniProtKB/TrEMBL
  ENSSSCP00000066367 UniProtKB/TrEMBL
  ENSSSCP00000069856 UniProtKB/TrEMBL
  ENSSSCP00070039040 UniProtKB/TrEMBL
  ENSSSCP00070039248 UniProtKB/TrEMBL
  ENSSSCP00070039387 UniProtKB/TrEMBL
  ENSSSCP00070039426 UniProtKB/TrEMBL
  ENSSSCP00070039494 UniProtKB/TrEMBL
  ENSSSCP00070039526 UniProtKB/TrEMBL
  ENSSSCP00070039675 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017366 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000022813 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000031044 UniProtKB/TrEMBL
  ENSSSCT00000041543 UniProtKB/TrEMBL
  ENSSSCT00000070397 UniProtKB/TrEMBL
  ENSSSCT00000076758 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000090247 UniProtKB/TrEMBL
  ENSSSCT00000091496 UniProtKB/TrEMBL
  ENSSSCT00070046274 UniProtKB/TrEMBL
  ENSSSCT00070046513 UniProtKB/TrEMBL
  ENSSSCT00070046692 UniProtKB/TrEMBL
  ENSSSCT00070046739 UniProtKB/TrEMBL
  ENSSSCT00070046817 UniProtKB/TrEMBL
  ENSSSCT00070046855 UniProtKB/TrEMBL
  ENSSSCT00070047026 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Mit_carrier UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
NCBI Gene SLC25A12 ENTREZGENE
Pfam Mito_carr UniProtKB/TrEMBL
PRINTS MITOCARRIER UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  SOLCAR UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
UniProt A0A286ZQ07_PIG UniProtKB/TrEMBL
  A0A4X1V9B4_PIG UniProtKB/TrEMBL
  A0A4X1VBJ5_PIG UniProtKB/TrEMBL
  A0A4X1VCD4_PIG UniProtKB/TrEMBL
  A0A4X1VCT0_PIG UniProtKB/TrEMBL
  A0A4X1VDP3_PIG UniProtKB/TrEMBL
  A0A5G2QBW2_PIG UniProtKB/TrEMBL
  A0A5G2QQF8_PIG UniProtKB/TrEMBL
  A0A5G2QQP2_PIG UniProtKB/TrEMBL
  A0A5G2QY62_PIG UniProtKB/TrEMBL
  F1S086_PIG UniProtKB/TrEMBL
  I3L614_PIG UniProtKB/TrEMBL
  I3L8T2_PIG UniProtKB/TrEMBL
UniProt Secondary M3VK21 UniProtKB/TrEMBL
VGNC ID VGNC:95502 ENTREZGENE