P2RY1 (purinergic receptor P2Y1) - Rat Genome Database
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Gene: P2RY1 (purinergic receptor P2Y1) Sus scrofa
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Symbol: P2RY1
Name: purinergic receptor P2Y1
RGD ID: 14101449
Description: ENCODES a protein that exhibits A1 adenosine receptor binding (ortholog); ADP binding (ortholog); G protein-coupled ATP receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); aging (ortholog); blood vessel diameter maintenance (ortholog); ASSOCIATED WITH Brain Injuries (ortholog); impotence (ortholog); thrombosis (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: P2Y purinoceptor 1; P2Y1 receptor; P2Y1R; purinergic receptor P2Y, G-protein coupled, 1
Orthologs:
Homo sapiens (human) : P2RY1 (purinergic receptor P2Y1)  HGNC  Alliance
Mus musculus (house mouse) : P2ry1 (purinergic receptor P2Y, G-protein coupled 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : P2ry1 (purinergic receptor P2Y1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2ry1 (purinergic receptor P2Y1)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RY1 (purinergic receptor P2Y1)
Canis lupus familiaris (dog) : P2RY1 (purinergic receptor P2Y1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2ry1 (purinergic receptor P2Y1)
Chlorocebus sabaeus (African green monkey) : P2RY1 (purinergic receptor P2Y1)
Heterocephalus glaber (naked mole-rat) : P2ry1 (purinergic receptor P2Y1)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1392,991,043 - 92,997,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11392,991,150 - 92,997,702 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213101,032,051 - 101,038,362 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (ISO)
aging  (ISO)
blood vessel diameter maintenance  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to purine-containing compound  (IEA)
eating behavior  (ISO)
G protein-coupled adenosine receptor signaling pathway  (ISO)
G protein-coupled purinergic nucleotide receptor signaling pathway  (IEA)
G protein-coupled receptor signaling pathway  (ISO)
glial cell migration  (ISO)
microglial cell activation  (ISO)
negative regulation of binding  (ISO)
negative regulation of norepinephrine secretion  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IEA)
platelet activation  (IEA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of hormone secretion  (ISO)
positive regulation of inositol trisphosphate biosynthetic process  (ISO)
positive regulation of ion transport  (IEA)
positive regulation of penile erection  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
protein localization to plasma membrane  (ISO)
regulation of cell shape  (IEA)
regulation of presynaptic cytosolic calcium ion concentration  (ISO)
regulation of signaling receptor activity  (ISO)
regulation of synaptic vesicle exocytosis  (ISO)
relaxation of muscle  (IEA)
response to growth factor  (ISO)
response to mechanical stimulus  (ISO)
sensory perception of pain  (ISO)
signal transduction involved in regulation of gene expression  (ISO)
wound healing  (ISO)

References
Additional References at PubMed
PMID:17167068   PMID:17294140  


Genomics

Comparative Map Data
P2RY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1392,991,043 - 92,997,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11392,991,150 - 92,997,702 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213101,032,051 - 101,038,362 (+)NCBISscrofa10.2Sscrofa10.2susScr3
P2RY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3152,835,131 - 152,841,439 (+)EnsemblGRCh38hg38GRCh38
GRCh383152,835,131 - 152,841,439 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373152,552,736 - 152,555,845 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363154,035,426 - 154,038,535 (+)NCBINCBI36hg18NCBI36
Build 343154,035,433 - 154,038,539NCBI
Celera3150,971,424 - 150,974,533 (+)NCBI
Cytogenetic Map3q25.2NCBI
HuRef3149,943,255 - 149,946,364 (+)NCBIHuRef
CHM1_13152,516,197 - 152,522,943 (+)NCBICHM1_1
P2ry1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39360,910,206 - 60,916,403 (+)NCBI
GRCm38361,002,785 - 61,008,982 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl361,002,795 - 61,008,982 (+)EnsemblGRCm38mm10GRCm38
MGSCv37360,806,717 - 60,812,901 (+)NCBIGRCm37mm9NCBIm37
MGSCv36361,090,724 - 61,096,908 (+)NCBImm8
Celera360,703,955 - 60,710,141 (+)NCBICelera
Cytogenetic Map3E1NCBI
P2ry1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02151,314,818 - 151,320,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2151,314,818 - 151,320,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02170,730,012 - 170,735,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42150,460,361 - 150,465,855 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12150,410,323 - 150,415,818 (+)NCBI
Celera2139,634,729 - 139,640,224 (+)NCBICelera
Cytogenetic Map2q31NCBI
P2ry1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554484,366,706 - 4,372,626 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554484,366,706 - 4,372,626 (+)NCBIChiLan1.0ChiLan1.0
P2RY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13157,426,423 - 157,432,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3157,426,692 - 157,427,813 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03149,859,748 - 149,865,873 (+)NCBIMhudiblu_PPA_v0panPan3
P2RY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2347,249,496 - 47,253,203 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12347,249,496 - 47,253,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
P2ry1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936519865,756 - 872,466 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RY1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11537,822,474 - 37,827,245 (-)NCBI
P2ry1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473030,470,894 - 30,478,269 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 2
Low 8 3 3 4 21 2 3 3
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012831   ⟹   ENSSSCP00000012491
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1392,991,043 - 92,997,700 (+)Ensembl
RefSeq Acc Id: XM_005669935   ⟹   XP_005669992
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11392,991,150 - 92,997,702 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005669936   ⟹   XP_005669993
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11392,991,512 - 92,997,702 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001300377
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11392,991,387 - 92,997,702 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005669992 (Get FASTA)   NCBI Sequence Viewer  
  XP_005669993 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAW80605 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005669992   ⟸   XM_005669935
- UniProtKB: F1SJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669993   ⟸   XM_005669936
- UniProtKB: F1SJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000012491   ⟸   ENSSSCT00000012831
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070003644 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012491 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070005556 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012831 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070006815 UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  P2Y1_rcpt UniProtKB/TrEMBL
KEGG Report ssc:503666 UniProtKB/TrEMBL
NCBI Gene P2RY1 ENTREZGENE
PANTHER PTHR24231:SF2 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  P2Y1PRNOCPTR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniGene Ssc.36621 ENTREZGENE
UniProt A0A4X1STK6_PIG UniProtKB/TrEMBL
  F1SJM6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91122 ENTREZGENE