HES2 (hes family bHLH transcription factor 2)

Gene: HES2 (hes family bHLH transcription factor 2) Sus scrofa

Analyze

Symbol:

HES2

Name:

hes family bHLH transcription factor 2

RGD ID:

14098394

Description:

ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hairy and enhancer of split 2; transcription factor HES-2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	67,276,777 - 67,279,603 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	67,276,774 - 67,279,617 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	62,229,965 - 62,231,952 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior pattern specification (IBA,IEA)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IEA)

regulation of neurogenesis (IBA,IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

double-stranded DNA binding (ISO)

protein dimerization activity (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HES2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	67,276,777 - 67,279,603 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	67,276,774 - 67,279,617 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	62,229,965 - 62,231,952 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HES2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	6,415,232 - 6,419,919 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	6,412,418 - 6,424,670 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	6,475,292 - 6,479,979 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	6,397,883 - 6,402,566 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	5,589,803 - 5,594,490 (-)	NCBI		Celera
Cytogenetic Map	1	p36.31	NCBI
HuRef	1	5,622,794 - 5,627,481 (-)	NCBI		HuRef
CHM1_1	1	6,463,852 - 6,468,539 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	5,940,873 - 5,945,560 (-)	NCBI		T2T-CHM13v2.0

Hes2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	152,243,324 - 152,246,926 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	152,243,324 - 152,246,926 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	152,158,867 - 152,162,469 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	152,158,867 - 152,162,469 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	151,532,976 - 151,536,578 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	151,002,667 - 151,006,269 (+)	NCBI		MGSCv36	mm8
Celera	4	154,445,172 - 154,448,774 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	82.92	NCBI

Hes2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	167,947,948 - 167,964,660 (+)	NCBI		GRCr8
mRatBN7.2	5	162,667,190 - 162,668,235 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,667,190 - 162,668,235 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	165,370,341 - 165,371,386 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,191,934 - 167,192,979 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	167,154,132 - 167,155,177 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	169,338,097 - 169,339,142 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,338,097 - 169,339,142 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	172,892,583 - 172,898,886 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	169,389,231 - 169,390,276 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	169,399,418 - 169,400,464 (+)	NCBI
Celera	5	160,899,190 - 160,900,235 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Hes2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	6,160,231 - 6,164,379 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	6,158,863 - 6,161,289 (+)	NCBI	ChiLan1.0	ChiLan1.0

HES2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	221,808,848 - 221,814,505 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	220,450,207 - 220,456,162 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	5,175,124 - 5,179,785 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	6,431,208 - 6,435,896 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	6,429,281 - 6,435,896 (-)	Ensembl	panpan1.1		panPan2

HES2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	60,275,645 - 60,279,327 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	60,278,043 - 60,279,181 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	60,285,435 - 60,289,103 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	60,491,528 - 60,495,196 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	60,494,060 - 60,495,062 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	60,491,012 - 60,494,680 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	60,357,589 - 60,361,257 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	60,759,187 - 60,762,855 (-)	NCBI		UU_Cfam_GSD_1.0

Hes2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	30,725,287 - 30,731,376 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	1,209,885 - 1,216,424 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936623	1,213,281 - 1,215,879 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HES2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	125,325,043 - 125,327,076 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	125,325,167 - 125,326,107 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	29,381,643 - 29,383,685 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hes2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624818	5,045,170 - 5,047,998 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HES2
52 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium								1
Low	7	2		3	2	1		1	1
Below cutoff	3	2	2	2		8	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003127529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP102449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000049564 ⟹ ENSSSCP00000039209

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	67,276,777 - 67,279,603 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000079222 ⟹ ENSSSCP00000074179

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	67,278,681 - 67,279,603 (-)	Ensembl

RefSeq Acc Id:

XM_003127529 ⟹ XP_003127577

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	67,276,774 - 67,279,617 (-)	NCBI

Sequence:

show sequence

GCGGGCGTAGCGCGCACTCCACTGGCTGCCGATCCGGCTGCGGACGGGACCTCCCTGCGAGCCT
CGGTCTCCGCTCCGTGTCAGGGCAGGCACAGGGCTCTCAAGCGCGGGCCCTGCAGCCGCACTGC
TTTCCTGCCAAGCATGGGGCTGCCTCGAAGGGCAGGGGACCCAGCGGAGCTGCGAAAGAACCTG
AAGCCCCTGCTGGAGAAGCGCCGCCGCGCGCGCATCAACGCGAGCCTGAGCCAGCTCAAGGGGC
TCATCCTGCCGCTCCTGGGCAGGGAGAGCTCTCACTACTCGAAGCTGGAGAAGGCGGACATCCT
GGAAATGACCGTGCGCTTCCTGCAGGAGCTGCCTGCGTCCTCCTGCCCGACGGCAGCGCCCACG
TCCTCCGACAGCTACCGCGAAGGCTACCGAGCTTGTCTGGCACGCCTGGCCCGCGTGCTACCTG
CTTGCCGTGTCCTGGAGCCTGCTCTGAGCGCCCGCCTGTTGGAGCACCTGCGCCGGAGGGCGGC
CTGTGCCACCCCCGACAGCGGACGCGCTGGGGACCCCAGTGGCCCACCCGCGCCCTCCCCGCCG
CCTGCACCTGCACCCTCACCGCCGGTGCCGCCCCGTGGCCCTAGCCTCTGGCGGCCCTGGTAGC
CCCCTGGCCGGTCCACAGACCCTGCTGACTACCAGGGACCAAGAGCACTAGACAGACTGAGAAA
GTTCTTGGCGGTGGCTGGGTTTTCCACCCGGAGGGACCAGCCTGGTACCAGGCCAGAACTGGAT
ATTTGTGTGGCCGACTGAAGTCCACGGAGGCTCAGGAAATAAGGGGACAGGCCCAGCCTCAGCC
CCCACTTAGGGTGTCAGGGCTGGTTGGTGAAGGGGCAGGTGGTTGCGGGGATGGGGGTAAGACG
CCTCCCACCCCAGGTGGTGGAAGGGCTCTAGAACTGGGCCAGCCACAGCTTCCCCGGGCAGCCC
ACACACCTGCCCTGGAGCTGGCACCAGCCCAAAGGCTGGGCCAGGAGCTCACCTGAGCCAGGTG
CAGCCATATGCTCTGACTGGTCCCTGCTTTCCTGACCCTGCTTGGGCCTGCCTCCTCACCAGCT
CAGCTTGAGAACTGCTGGACACACAGCAGCGATGGCCTGAGGGGCCCTGCAGGCTGGGGAGCCA
TGACCTTCACTCGAGGGCTCTCCCACCTGAAGCTTCTGATTCCAGGACTGATGCCACCAGGATT
GTGTGTCGCTGGGGGTGGGGACCTCCTCAGGCAGTTGCAGGAAGGATTTAATTCCCCAAGCATT
AGGGTCACACCTGAGTATGGCTCACCTGGCCAGGAGGTCTTGGGAGTGTGAAGAAGGGGTGGCC
CAAGAATAAGGGTGCCCAGTGGCCTCAAGGAAGCTTGTCACCTTGAAGAGGCTGGGTCCGGCCC
AGAACCATGGCTGTGTGAGGTGAGTGGGGCCCAGGTCCTGGAGCAGCAGAAAGTCAAGGCATAT
GCAGCAGGTAAAGGAACAGGAACCCCTTTCCTCGTTTTCTCTTTCAAACTGCTCCTTGCTATTG
TCAAGACAGCTTACGGGAAGCAACTTGTTTCTTTTTTATTTTTATTTTTTTTTGTCTTTTTGCC
ATTTCTTGGGCTGCTCCCACGCCATATGGAGGTTCCCAGGCTAGGGGTCCAATCGGAGCTGTAG
CCACCGGCCTACGCCAGAGCCACAGCAACACAGGATCTGAGCTGCATCTGCAACCTACCCCATA
GCTCACAGCAACGCCGGATCGTTAACCCACCGAGTAAGGGCAGGGATCGAACCCGCAACCTCAT
GGTTCCTAGTCGGATTCGTTAACCACTGCGCCACAACGGGAACTCCAGCAGCTTGTTCTTAAGA
TGTTTCTTTCTGCCCCACGGAAGCCAGAGAGCCTTTGAAGACCAGAGAGGAGTCTGCAGATCCC
AGCAGTGGGTGCCCAAGAGAAGGCCAGAGTGCCTGCACTCACTTGCGGTCGTGTTCCCAGCATC
TCCTGGGGACTGGCTGGGCATTTATGGGAATCGGGAGTCCTGCCCCTTCCTATCCCGTCCAACA
GCCTGTGTGAGAGTCCAGGACCCAAGGGACAAGAAGACAGAGCTGACAGAGGTGGGGGTGGTCA
CCAAGCTGAATGATGCCACATAAACTCATGATGATAACCTTGGCACCAATTGGGGTGGCAGGAT
GTGGGGAAGCTGTGGGCACATTATGGAAGAGGTCAAGGCTGAGAACTACAGGGTGAGCCCATCA
AGGGGGCTGTCCTATGGCCTGTCTGGGCGCTGCTGGCTGGACTGTAAGCCCCTGGAGGGCAGGG
CTGGGGCTTAGCGGACCTCTTTGTCCCCAAGGCATTTGGCGTGTGGCGAGTGCTCAATAAACAT
TGTGAACAAATGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003127577	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000039209
	ENSSSCP00000039209.1
	ENSSSCP00000074179.1
	ENSSSCP00015042065.1
	ENSSSCP00015042083.1
	ENSSSCP00025048137.1
	ENSSSCP00025048139.1
	ENSSSCP00030046995.1
	ENSSSCP00030047000.1
	ENSSSCP00035001002.1
	ENSSSCP00035001003.1
	ENSSSCP00040019736.1
	ENSSSCP00040019749.1
	ENSSSCP00040019772.1
	ENSSSCP00045024544.1
	ENSSSCP00045024580.1
	ENSSSCP00045024612.1
	ENSSSCP00050037590.1
	ENSSSCP00055006446.1
	ENSSSCP00055006448.1
	ENSSSCP00055006451.1
	ENSSSCP00060024653.1
	ENSSSCP00060024654.1
	ENSSSCP00065036423.1
	ENSSSCP00070050597.1
	ENSSSCP00070050598.1
	ENSSSCP00070050599.1

RefSeq Acc Id:	XP_003127577 ⟸ XM_003127529
- UniProtKB:	A0A287A5I8 (UniProtKB/TrEMBL), A0A4X1W9X8 (UniProtKB/TrEMBL), A0A8D1NGK0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGLPRRAGDPAELRKNLKPLLEKRRRARINASLSQLKGLILPLLGRESSHYSKLEKADILEMTV RFLQELPASSCPTAAPTSSDSYREGYRACLARLARVLPACRVLEPALSARLLEHLRRRAACATP DSGRAGDPSGPPAPSPPPAPAPSPPVPPRGPSLWRPW hide sequence

RefSeq Acc Id:

ENSSSCP00000039209 ⟸ ENSSSCT00000049564

RefSeq Acc Id:

ENSSSCP00000074179 ⟸ ENSSSCT00000079222

Protein Domains

bHLH Orange

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000034297	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015075369	UniProtKB/TrEMBL
	ENSSSCG00025077056	UniProtKB/TrEMBL
	ENSSSCG00030072756	UniProtKB/TrEMBL
	ENSSSCG00035002338	UniProtKB/TrEMBL
	ENSSSCG00040035035	UniProtKB/TrEMBL
	ENSSSCG00045020723	UniProtKB/TrEMBL
	ENSSSCG00050064358	UniProtKB/TrEMBL
	ENSSSCG00055004140	UniProtKB/TrEMBL
	ENSSSCG00060042519	UniProtKB/TrEMBL
	ENSSSCG00065061019	UniProtKB/TrEMBL
	ENSSSCG00070029562	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000049564	ENTREZGENE
	ENSSSCT00000049564.3	UniProtKB/TrEMBL
	ENSSSCT00000079222.2	UniProtKB/TrEMBL
	ENSSSCT00015101520.1	UniProtKB/TrEMBL
	ENSSSCT00015101566.1	UniProtKB/TrEMBL
	ENSSSCT00025106961.1	UniProtKB/TrEMBL
	ENSSSCT00025106964.1	UniProtKB/TrEMBL
	ENSSSCT00030101877.1	UniProtKB/TrEMBL
	ENSSSCT00030101886.1	UniProtKB/TrEMBL
	ENSSSCT00035002930.1	UniProtKB/TrEMBL
	ENSSSCT00035002932.1	UniProtKB/TrEMBL
	ENSSSCT00040047115.1	UniProtKB/TrEMBL
	ENSSSCT00040047161.1	UniProtKB/TrEMBL
	ENSSSCT00040047229.1	UniProtKB/TrEMBL
	ENSSSCT00045035363.1	UniProtKB/TrEMBL
	ENSSSCT00045035402.1	UniProtKB/TrEMBL
	ENSSSCT00045035439.1	UniProtKB/TrEMBL
	ENSSSCT00050087637.1	UniProtKB/TrEMBL
	ENSSSCT00055008160.1	UniProtKB/TrEMBL
	ENSSSCT00055008162.1	UniProtKB/TrEMBL
	ENSSSCT00055008167.1	UniProtKB/TrEMBL
	ENSSSCT00060057643.1	UniProtKB/TrEMBL
	ENSSSCT00060057644.1	UniProtKB/TrEMBL
	ENSSSCT00065083589.1	UniProtKB/TrEMBL
	ENSSSCT00070059418.1	UniProtKB/TrEMBL
	ENSSSCT00070059419.1	UniProtKB/TrEMBL
	ENSSSCT00070059421.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
	Orange_dom	UniProtKB/TrEMBL
KEGG Report	ssc:100515666	UniProtKB/TrEMBL
NCBI Gene	HES2	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED	UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR HES-2	UniProtKB/TrEMBL
Pfam	Hairy_orange	UniProtKB/TrEMBL
	HLH	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
	ORANGE	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
	ORANGE	UniProtKB/TrEMBL
Superfamily-SCOP	Orange domain-like	UniProtKB/TrEMBL
	SSF47459	UniProtKB/TrEMBL
UniProt	A0A287A5I8	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W8L0_PIG	UniProtKB/TrEMBL
	A0A4X1W8V9_PIG	UniProtKB/TrEMBL
	A0A4X1W9X8	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2RA40_PIG	UniProtKB/TrEMBL
	A0A8D0Q385_PIG	UniProtKB/TrEMBL
	A0A8D1EB50_PIG	UniProtKB/TrEMBL
	A0A8D1EDP0_PIG	UniProtKB/TrEMBL
	A0A8D1NGK0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1VGW5_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:88855	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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