GEM (GTP binding protein overexpressed in skeletal muscle) - Rat Genome Database

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Gene: GEM (GTP binding protein overexpressed in skeletal muscle) Sus scrofa
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Symbol: GEM
Name: GTP binding protein overexpressed in skeletal muscle
RGD ID: 14096432
Description: ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN chromosome organization (inferred); metaphase plate congression (inferred); mitotic cell cycle (inferred); FOUND IN cytoplasmic side of plasma membrane (inferred); midbody (inferred); mitotic spindle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: GTP-binding protein GEM
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl442,249,479 - 42,471,937 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1442,458,591 - 42,471,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2445,876,630 - 45,889,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
GEM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl442,249,479 - 42,471,937 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1442,458,591 - 42,471,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2445,876,630 - 45,889,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GEM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl894,249,253 - 94,262,350 (-)EnsemblGRCh38hg38GRCh38
GRCh38894,249,249 - 94,262,345 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37895,261,481 - 95,274,547 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36895,330,657 - 95,343,733 (-)NCBINCBI36hg18NCBI36
Build 34895,330,662 - 95,343,733NCBI
Celera891,447,594 - 91,460,660 (-)NCBI
Cytogenetic Map8q22.1NCBI
HuRef890,470,565 - 90,483,631 (-)NCBIHuRef
CHM1_1895,301,787 - 95,314,853 (-)NCBICHM1_1
Gem
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39411,702,379 - 11,714,993 (+)NCBIGRCm39mm39
GRCm39 Ensembl411,704,457 - 11,714,752 (+)Ensembl
GRCm38411,704,447 - 11,714,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl411,704,457 - 11,714,752 (+)EnsemblGRCm38mm10GRCm38
MGSCv37411,631,594 - 11,642,140 (+)NCBIGRCm37mm9NCBIm37
MGSCv36411,631,604 - 11,641,899 (+)NCBImm8
Celera411,515,538 - 11,526,084 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map45.34NCBI
Gem
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2525,214,309 - 25,225,222 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl525,214,309 - 25,225,222 (+)Ensembl
Rnor_6.0525,339,479 - 25,353,661 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl525,349,928 - 25,353,661 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0530,050,664 - 30,062,666 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4525,809,543 - 26,008,249 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1526,004,470 - 26,008,270 (+)NCBI
Celera524,546,414 - 24,557,484 (+)NCBICelera
Cytogenetic Map5q13NCBI
Gem
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541710,475,822 - 10,487,825 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541710,475,967 - 10,486,879 (-)NCBIChiLan1.0ChiLan1.0
GEM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1892,817,028 - 92,830,133 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl892,817,028 - 92,830,133 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0890,872,855 - 90,885,969 (-)NCBIMhudiblu_PPA_v0panPan3
GEM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12939,016,543 - 39,037,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2939,025,483 - 39,037,403 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2939,177,842 - 39,199,013 (-)NCBI
ROS_Cfam_1.02939,220,477 - 39,241,164 (-)NCBI
UMICH_Zoey_3.12939,234,088 - 39,255,249 (-)NCBI
UNSW_CanFamBas_1.02939,229,276 - 39,250,433 (-)NCBI
UU_Cfam_GSD_1.02939,670,894 - 39,692,020 (-)NCBI
Gem
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530340,516,800 - 40,530,076 (+)NCBI
SpeTri2.0NW_0049365447,262,629 - 7,275,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GEM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1889,219,484 - 89,232,788 (-)NCBI
ChlSab1.1 Ensembl889,218,782 - 89,232,753 (-)Ensembl
Vero_WHO_p1.0NW_02366603951,615,735 - 51,629,058 (+)NCBI
Gem
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247631,654,369 - 1,666,538 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 1 1 2 1 1 1
Low 7 3 2 3 2 22 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006692   ⟹   ENSSSCP00000006512
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl442,249,479 - 42,471,929 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000033083   ⟹   ENSSSCP00000028615
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl442,459,462 - 42,471,937 (+)Ensembl
RefSeq Acc Id: XM_001926976   ⟹   XP_001927011
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1442,458,591 - 42,471,941 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005662965   ⟹   XP_005663022
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1442,458,838 - 42,471,941 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001927011 (Get FASTA)   NCBI Sequence Viewer  
  XP_005663022 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_001927011   ⟸   XM_001926976
- Peptide Label: isoform X2
- UniProtKB: K7GL86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005663022   ⟸   XM_005662965
- Peptide Label: isoform X1
- UniProtKB: F1RY45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000006512   ⟸   ENSSSCT00000006692
RefSeq Acc Id: ENSSSCP00000028615   ⟸   ENSSSCT00000033083


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006105 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070014477 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000006512 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000028615 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070023637 UniProtKB/TrEMBL
  ENSSSCP00070023641 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006692 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000033083 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070028383 UniProtKB/TrEMBL
  ENSSSCT00070028386 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  RGK UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
KEGG Report ssc:404772 UniProtKB/TrEMBL
NCBI Gene GEM ENTREZGENE
Pfam Ras UniProtKB/TrEMBL
PIRSF GTP-binding_GEM UniProtKB/TrEMBL
PROSITE RAS UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/TrEMBL
UniProt A0A4X1U1R7_PIG UniProtKB/TrEMBL
  A0A4X1U6D0_PIG UniProtKB/TrEMBL
  F1RY45 ENTREZGENE
  F1RY50_PIG UniProtKB/TrEMBL
  K7GL86 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88410 ENTREZGENE