FSCN2 (fascin actin-bundling protein 2, retinal) - Rat Genome Database
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Gene: FSCN2 (fascin actin-bundling protein 2, retinal) Sus scrofa
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Symbol: FSCN2
Name: fascin actin-bundling protein 2, retinal
RGD ID: 14095967
Description: ENCODES a protein that exhibits actin filament binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN eye photoreceptor cell development (ortholog); ASSOCIATED WITH Leber congenital amaurosis (ortholog); macular degeneration (ortholog); retinitis pigmentosa (ortholog); FOUND IN actin cytoskeleton (ortholog); stereocilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: fascin homolog 2, actin-bundling protein, retinal; fascin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,300,225 - 1,313,421 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,300,286 - 1,311,562 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,143,345 - 1,156,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin cytoskeleton  (IBA,IEA,ISO)
cytoplasm  (IBA,IEA)
stereocilium  (IEA,ISO)

Molecular Function

References

Genomics

Comparative Map Data
FSCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,300,225 - 1,313,421 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,300,286 - 1,311,562 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,143,345 - 1,156,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FSCN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1781,528,396 - 81,537,130 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1781,528,377 - 81,537,130 (+)EnsemblGRCh38hg38GRCh38
GRCh381781,513,019 - 81,537,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,481,022 - 79,504,156 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh371779,495,403 - 79,504,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,110,012 - 77,114,632 (+)NCBINCBI36hg18NCBI36
Build 341777,110,016 - 77,114,631NCBI
Celera1776,139,079 - 76,148,244 (+)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1774,944,167 - 74,951,874 (+)NCBIHuRef
CHM1_11779,581,654 - 79,590,360 (+)NCBICHM1_1
Fscn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,250,991 - 120,258,999 (+)NCBIGRCm39mm39
GRCm3811120,360,165 - 120,368,173 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,361,534 - 120,368,168 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711120,222,848 - 120,229,487 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611120,177,624 - 120,184,261 (+)NCBImm8
Celera11132,096,284 - 132,102,924 (+)NCBICelera
Cytogenetic Map11E2NCBI
Fscn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210105,634,783 - 105,641,322 (+)NCBI
Rnor_6.0 Ensembl10109,533,487 - 109,540,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.010109,528,307 - 109,540,675 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,128,055 - 109,134,594 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,789,092 - 109,795,631 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110109,803,763 - 109,810,072 (+)NCBI
Celera10104,180,130 - 104,186,669 (+)NCBICelera
Cytogenetic Map10q32.3NCBI
Fscn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,526,830 - 1,533,775 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,526,830 - 1,533,775 (-)NCBIChiLan1.0ChiLan1.0
FSCN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11781,687,051 - 81,694,823 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1781,687,051 - 81,694,823 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01775,974,971 - 75,993,275 (+)NCBIMhudiblu_PPA_v0panPan3
FSCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl9617,609 - 621,882 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.19616,088 - 622,152 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fscn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365945,184,133 - 5,195,340 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSCN2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,472,582 - 73,482,440 (+)NCBI
ChlSab1.1 Ensembl1673,474,519 - 73,481,967 (+)Ensembl
Fscn2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480110,511,539 - 10,518,073 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 3 1 1 2 2 4 1 1 1
Below cutoff 5 1 2 1 11 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024097   ⟹   ENSSSCP00000022248
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl121,300,286 - 1,313,421 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061581   ⟹   ENSSSCP00000057954
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl121,300,225 - 1,305,901 (-)Ensembl
RefSeq Acc Id: XM_003357929   ⟹   XP_003357977
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1121,300,286 - 1,311,562 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003357977 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003357977   ⟸   XM_003357929
- Sequence:
RefSeq Acc Id: ENSSSCP00000057954   ⟸   ENSSSCT00000061581
RefSeq Acc Id: ENSSSCP00000022248   ⟸   ENSSSCT00000024097
Protein Domains
Fascin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070015918 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000022248 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000057954 UniProtKB/TrEMBL
  ENSSSCP00070026098 UniProtKB/TrEMBL
  ENSSSCP00070026109 UniProtKB/TrEMBL
  ENSSSCP00070026115 UniProtKB/TrEMBL
  ENSSSCP00070026120 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024097 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000061581 UniProtKB/TrEMBL
  ENSSSCT00070031305 UniProtKB/TrEMBL
  ENSSSCT00070031320 UniProtKB/TrEMBL
  ENSSSCT00070031326 UniProtKB/TrEMBL
  ENSSSCT00070031335 UniProtKB/TrEMBL
InterPro Actin-crosslinking UniProtKB/TrEMBL
  Fascin UniProtKB/TrEMBL
  Fascin-domain UniProtKB/TrEMBL
  Fascin_metazoans UniProtKB/TrEMBL
  FSCN2 UniProtKB/TrEMBL
NCBI Gene FSCN2 ENTREZGENE
PANTHER PTHR10551 UniProtKB/TrEMBL
  PTHR10551:SF24 UniProtKB/TrEMBL
Pfam Fascin UniProtKB/TrEMBL
PIRSF Fascin UniProtKB/TrEMBL
Superfamily-SCOP SSF50405 UniProtKB/TrEMBL
UniProt A0A287BMV6_PIG UniProtKB/TrEMBL
  A0A4X1U8J9_PIG UniProtKB/TrEMBL
  A0A4X1UB17_PIG UniProtKB/TrEMBL
  A0A4X1UB22_PIG UniProtKB/TrEMBL
  A0A4X1UCS3_PIG UniProtKB/TrEMBL
  I3LDW3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88249 ENTREZGENE