ARL2 (ADP ribosylation factor like GTPase 2) - Rat Genome Database

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Gene: ARL2 (ADP ribosylation factor like GTPase 2) Sus scrofa
Analyze
Symbol: ARL2
Name: ADP ribosylation factor like GTPase 2
RGD ID: 14090542
Description: ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN acetylcholine transport (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); genetic disease (ortholog); glycogen storage disease V (ortholog); FOUND IN cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADP-ribosylation factor-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,157,918 - 7,167,212 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,157,963 - 7,167,024 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,290,009 - 6,299,054 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,157,918 - 7,167,212 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,157,963 - 7,167,024 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,290,009 - 6,299,054 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,014,160 - 65,022,184 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,014,160 - 65,022,184 (+)EnsemblGRCh38hg38GRCh38
GRCh371164,781,632 - 64,789,656 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,538,162 - 64,546,232 (+)NCBINCBI36Build 36hg18NCBI36
Build 341164,538,244 - 64,546,231NCBI
Celera1162,107,517 - 62,115,588 (+)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,108,599 - 61,116,672 (+)NCBIHuRef
CHM1_11164,665,310 - 64,673,383 (+)NCBICHM1_1
T2T-CHM13v2.01165,007,423 - 65,015,448 (+)NCBIT2T-CHM13v2.0
Arl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,184,419 - 6,191,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,184,404 - 6,191,578 (-)EnsemblGRCm39 Ensembl
GRCm38196,134,389 - 6,141,137 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,134,374 - 6,141,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv37196,134,389 - 6,141,137 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,134,389 - 6,141,137 (-)NCBIMGSCv36mm8
Celera196,006,926 - 6,013,674 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
Arl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,863,422 - 212,875,425 (-)NCBIGRCr8
mRatBN7.21203,434,129 - 203,446,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,434,129 - 203,446,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,788,126 - 211,794,443 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,879,494 - 218,891,437 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,570,564 - 211,582,507 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,504,150 - 221,516,191 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,504,170 - 221,516,110 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,438,685 - 228,451,162 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,909,458 - 208,921,401 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,062,911 - 209,074,854 (-)NCBI
Celera1200,967,810 - 200,979,754 (-)NCBICelera
Cytogenetic Map1q43NCBI
Arl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,166,956 - 20,172,950 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,166,956 - 20,172,954 (-)NCBIChiLan1.0ChiLan1.0
ARL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2966,240,364 - 66,249,061 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,283,331 - 67,292,028 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,370,499 - 60,378,553 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,710,622 - 63,719,103 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,710,622 - 63,719,103 (+)Ensemblpanpan1.1panPan2
ARL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,169,225 - 52,175,782 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,776,887 - 50,783,568 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,210,429 - 53,217,136 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1853,210,429 - 53,216,908 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11852,305,656 - 52,312,387 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,879,935 - 51,886,600 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,675,103 - 52,681,799 (-)NCBIUU_Cfam_GSD_1.0
Arl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,893,846 - 7,900,384 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,336,079 - 4,343,061 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365994,336,190 - 4,343,007 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,212,903 - 9,219,985 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,213,123 - 9,219,927 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,596,406 - 106,603,482 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,370,917 - 21,377,425 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,363,110 - 21,377,415 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARL2
487 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 13
Low 10 4 3 5 1 10 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000051108   ⟹   ENSSSCP00000050487
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl27,157,964 - 7,167,212 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000070722   ⟹   ENSSSCP00000067984
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl27,157,918 - 7,167,002 (-)Ensembl
RefSeq Acc Id: XM_003122549   ⟹   XP_003122597
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.127,157,963 - 7,167,024 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013994122   ⟹   XP_013849576
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.127,157,963 - 7,166,997 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003122597   ⟸   XM_003122549
- Peptide Label: isoform X2
- UniProtKB: A0A287B226 (UniProtKB/TrEMBL),   A0A4X1V579 (UniProtKB/TrEMBL),   A0A8D0T8Z4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013849576   ⟸   XM_013994122
- Peptide Label: isoform X1
- UniProtKB: A0A8D0T8Z4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000050487   ⟸   ENSSSCT00000051108
RefSeq Acc Id: ENSSSCP00000067984   ⟸   ENSSSCT00000070722


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025070873 UniProtKB/TrEMBL
  ENSSSCG00030016430 UniProtKB/TrEMBL
  ENSSSCG00035078819 UniProtKB/TrEMBL
  ENSSSCG00040053723 UniProtKB/TrEMBL
  ENSSSCG00045019947 UniProtKB/TrEMBL
  ENSSSCG00050041063 UniProtKB/TrEMBL
  ENSSSCG00055026145 UniProtKB/TrEMBL
  ENSSSCG00060051305 UniProtKB/TrEMBL
  ENSSSCG00065029401 UniProtKB/TrEMBL
  ENSSSCG00070021717 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000051108 ENTREZGENE
  ENSSSCT00000051108.3 UniProtKB/TrEMBL
  ENSSSCT00000070722.2 UniProtKB/TrEMBL
  ENSSSCT00025097391.1 UniProtKB/TrEMBL
  ENSSSCT00025097625.1 UniProtKB/TrEMBL
  ENSSSCT00030022749.1 UniProtKB/TrEMBL
  ENSSSCT00035107792.1 UniProtKB/TrEMBL
  ENSSSCT00035107853.1 UniProtKB/TrEMBL
  ENSSSCT00040072724.1 UniProtKB/TrEMBL
  ENSSSCT00040072807.1 UniProtKB/TrEMBL
  ENSSSCT00040072857.1 UniProtKB/TrEMBL
  ENSSSCT00045034136.1 UniProtKB/TrEMBL
  ENSSSCT00045034290.1 UniProtKB/TrEMBL
  ENSSSCT00050055649.1 UniProtKB/TrEMBL
  ENSSSCT00055051821.1 UniProtKB/TrEMBL
  ENSSSCT00055052016.1 UniProtKB/TrEMBL
  ENSSSCT00060069826.1 UniProtKB/TrEMBL
  ENSSSCT00060069831.1 UniProtKB/TrEMBL
  ENSSSCT00065039676.1 UniProtKB/TrEMBL
  ENSSSCT00065039682.1 UniProtKB/TrEMBL
  ENSSSCT00070043145.1 UniProtKB/TrEMBL
  ENSSSCT00070043197.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Arl2 UniProtKB/TrEMBL
  ARL2/3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/TrEMBL
NCBI Gene ARL2 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 UniProtKB/TrEMBL
  PTHR45697 UniProtKB/TrEMBL
Pfam Arf UniProtKB/TrEMBL
PRINTS SAR1GTPBP UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  SAR UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287B226 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V579 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V5D3_PIG UniProtKB/TrEMBL
  A0A5G2QV21_PIG UniProtKB/TrEMBL
  A0A8D0T8Z4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KES9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:97885 ENTREZGENE