SLC6A19 (solute carrier family 6 member 19) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SLC6A19 (solute carrier family 6 member 19) Sus scrofa
Analyze
Symbol: SLC6A19
Name: solute carrier family 6 member 19
RGD ID: 14090471
Description: ENCODES a protein that exhibits neutral L-amino acid transmembrane transporter activity (inferred); symporter activity (inferred); INVOLVED IN amino acid transmembrane transport (ortholog); neutral amino acid transport (ortholog); response to nutrient (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 2 (ortholog); dopamine transporter deficiency syndrome (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (inferred); brush border membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium-dependent neutral amino acid transporter B(0)AT1; solute carrier family 6 (neutral amino acid transporter), member 19; system B0 neutral amino acid transporter SLC6A19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,293,943 - 79,310,922 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,293,940 - 79,310,922 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,952,505 - 85,969,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,293,943 - 79,310,922 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,293,940 - 79,310,922 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,952,505 - 85,969,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3851,201,595 - 1,225,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl51,201,595 - 1,225,111 (+)EnsemblGRCh38hg38GRCh38
GRCh3751,201,710 - 1,225,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,254,766 - 1,275,019 (+)NCBINCBI36Build 36hg18NCBI36
Celera51,238,608 - 1,262,115 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef51,183,086 - 1,206,530 (+)NCBIHuRef
CHM1_151,198,248 - 1,225,118 (+)NCBICHM1_1
T2T-CHM13v2.051,108,484 - 1,132,085 (+)NCBIT2T-CHM13v2.0
Slc6a19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391373,827,864 - 73,848,899 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1373,827,864 - 73,852,984 (-)EnsemblGRCm39 Ensembl
GRCm381373,679,745 - 73,700,780 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1373,679,745 - 73,704,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv371373,818,605 - 73,838,143 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,147,159 - 74,166,697 (-)NCBIMGSCv36mm8
Celera1376,010,112 - 76,029,756 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.14NCBI
Slc6a19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,414,744 - 31,434,932 (+)NCBIGRCr8
mRatBN7.2129,586,191 - 29,604,964 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,586,195 - 29,604,962 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,387,324 - 29,406,097 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,387,174 - 35,405,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,587,954 - 29,606,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,199,869 - 32,218,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,199,810 - 32,220,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,624,561 - 33,643,496 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,393,331 - 30,412,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera128,234,184 - 28,252,964 (+)NCBICelera
Cytogenetic Map1p11NCBI
Slc6a19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504616,768 - 633,654 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955504617,683 - 633,594 (+)NCBIChiLan1.0ChiLan1.0
SLC6A19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,461,963 - 1,482,056 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,248,802 - 1,272,508 (+)Ensemblpanpan1.1panPan2
SLC6A19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,329,126 - 11,344,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,329,111 - 11,344,293 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3415,838,998 - 15,854,198 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,229,799 - 11,244,920 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,229,784 - 11,244,965 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,280,591 - 11,295,588 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,260,140 - 11,275,298 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,471,162 - 11,486,159 (-)NCBIUU_Cfam_GSD_1.0
Slc6a19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,352,755 - 244,371,592 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815515,762 - 532,917 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815515,928 - 532,877 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.141,031,236 - 1,053,815 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl41,033,125 - 1,056,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,594,889 - 35,615,960 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751591,754 - 607,693 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751591,846 - 606,362 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC6A19
483 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system renal system
High
Medium 4 1
Low 1 1
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018638   ⟹   ENSSSCP00000018137
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,293,943 - 79,310,922 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000083222   ⟹   ENSSSCP00000067384
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,293,950 - 79,310,842 (-)Ensembl
RefSeq Acc Id: XM_003359855   ⟹   XP_003359903
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11679,293,940 - 79,310,922 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003359903 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB17280 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000018137
  ENSSSCP00000018137.3
  ENSSSCP00000067384.1
  ENSSSCP00015030671.1
  ENSSSCP00015030690.1
  ENSSSCP00015030773.1
  ENSSSCP00015030815.1
  ENSSSCP00070015994.1
Reference Protein Sequences
RefSeq Acc Id: XP_003359903   ⟸   XM_003359855
- UniProtKB: A0A4X1TH85 (UniProtKB/TrEMBL),   A0A8D0U7P2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067384   ⟸   ENSSSCT00000083222
RefSeq Acc Id: ENSSSCP00000018137   ⟸   ENSSSCT00000018638


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017120 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015057304 UniProtKB/TrEMBL
  ENSSSCG00070009899 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018638 ENTREZGENE
  ENSSSCT00000018638.4 UniProtKB/TrEMBL
  ENSSSCT00000083222.1 UniProtKB/TrEMBL
  ENSSSCT00015076360.1 UniProtKB/TrEMBL
  ENSSSCT00015076402.1 UniProtKB/TrEMBL
  ENSSSCT00015076583.1 UniProtKB/TrEMBL
  ENSSSCT00015076666.1 UniProtKB/TrEMBL
  ENSSSCT00070019232.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  Na/ntran_symport_orphan UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
KEGG Report ssc:641346 UniProtKB/TrEMBL
NCBI Gene SLC6A19 ENTREZGENE
PANTHER PTHR11616 UniProtKB/TrEMBL
  SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
  ORPHTRNSPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A4X1TH85 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QRJ4_PIG UniProtKB/TrEMBL
  A0A8D0PAC4_PIG UniProtKB/TrEMBL
  A0A8D0PHD0_PIG UniProtKB/TrEMBL
  A0A8D0U7P2 ENTREZGENE, UniProtKB/TrEMBL
  F1S025_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93160 ENTREZGENE