HS3ST6 (heparan sulfate-glucosamine 3-sulfotransferase 6) - Rat Genome Database

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Gene: HS3ST6 (heparan sulfate-glucosamine 3-sulfotransferase 6) Sus scrofa
Analyze
Symbol: HS3ST6
Name: heparan sulfate-glucosamine 3-sulfotransferase 6
RGD ID: 14086535
Description: ENCODES a protein that exhibits [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN blastocyst hatching (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); Hereditary Angioedema 8 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heparan sulfate glucosamine 3-O-sulfotransferase 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,032,464 - 40,038,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,029,927 - 40,038,803 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
HS3ST6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,032,464 - 40,038,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,029,927 - 40,038,803 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HS3ST6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,911,475 - 1,920,940 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,911,475 - 1,918,415 (-)EnsemblGRCh38hg38GRCh38
GRCh37161,961,476 - 1,968,416 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,901,465 - 1,908,232 (-)NCBINCBI36Build 36hg18NCBI36
Build 34161,901,592 - 1,908,232NCBI
Celera162,173,672 - 2,180,439 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,886,409 - 1,892,882 (-)NCBIHuRef
CHM1_1161,961,600 - 1,968,371 (-)NCBICHM1_1
T2T-CHM13v2.0161,930,559 - 1,940,903 (-)NCBIT2T-CHM13v2.0
Hs3st6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,971,565 - 24,977,664 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,971,962 - 24,977,658 (+)EnsemblGRCm39 Ensembl
GRCm381724,752,988 - 24,758,690 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,752,988 - 24,758,684 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,889,948 - 24,895,629 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,480,603 - 24,486,284 (+)NCBIMGSCv36mm8
Celera1725,276,333 - 25,283,676 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Hs3st6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,286,555 - 14,292,660 (+)NCBIGRCr8
mRatBN7.21013,781,999 - 13,788,133 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,781,993 - 13,788,133 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,528,734 - 18,534,712 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,017,594 - 18,023,572 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,516,804 - 13,522,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,122,856 - 14,128,984 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,122,878 - 14,128,983 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,938,606 - 13,944,712 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,010,051 - 14,016,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,461,730 - 13,467,645 (+)NCBICelera
Cytogenetic Map10q12NCBI
Hs3st6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,337,106 - 15,347,251 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,337,106 - 15,344,453 (+)NCBIChiLan1.0ChiLan1.0
HS3ST6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,433,301 - 2,442,801 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,215,397 - 6,224,383 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016789,542 - 796,792 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,994,757 - 2,001,594 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,994,864 - 2,001,615 (-)Ensemblpanpan1.1panPan2
HS3ST6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,997,299 - 39,002,611 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,235,317 - 40,241,791 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,312,648 - 39,319,120 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,312,544 - 39,319,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,989,414 - 38,995,886 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,961,746 - 38,968,219 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,440,600 - 39,447,074 (+)NCBIUU_Cfam_GSD_1.0
Hs3st6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,603,640 - 104,609,504 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,100,040 - 2,105,658 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
HS3ST6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,811,600 - 1,818,668 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,811,872 - 1,818,483 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,259,521 - 29,266,319 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hs3st6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913323,854 - 331,489 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913323,778 - 330,347 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HS3ST6
18 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038189   ⟹   ENSSSCP00000042488
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl340,032,571 - 40,041,393 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000048851   ⟹   ENSSSCP00000050098
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl340,038,056 - 40,038,799 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000098158   ⟹   ENSSSCP00000075621
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl340,032,464 - 40,038,870 (+)Ensembl
RefSeq Acc Id: XM_021086794   ⟹   XP_020942453
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1340,029,931 - 40,038,803 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086795   ⟹   XP_020942454
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1340,029,927 - 40,038,803 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020942454   ⟸   XM_021086795
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020942453   ⟸   XM_021086794
- Peptide Label: isoform X1
- UniProtKB: A0A287AF31 (UniProtKB/TrEMBL),   A0A4X1VXR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000050098   ⟸   ENSSSCT00000048851
RefSeq Acc Id: ENSSSCP00000042488   ⟸   ENSSSCT00000038189
RefSeq Acc Id: ENSSSCP00000075621   ⟸   ENSSSCT00000098158
Protein Domains
Sulfotransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031216 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015027764 UniProtKB/TrEMBL
  ENSSSCG00025020398 UniProtKB/TrEMBL
  ENSSSCG00030036950 UniProtKB/TrEMBL
  ENSSSCG00035049993 UniProtKB/TrEMBL
  ENSSSCG00040070154 UniProtKB/TrEMBL
  ENSSSCG00050078120 UniProtKB/TrEMBL
  ENSSSCG00065064796 UniProtKB/TrEMBL
  ENSSSCG00070027537 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000048851.3 UniProtKB/TrEMBL
  ENSSSCT00000098158 ENTREZGENE
  ENSSSCT00000098158.1 UniProtKB/TrEMBL
  ENSSSCT00015036824.1 UniProtKB/TrEMBL
  ENSSSCT00025027717.1 UniProtKB/TrEMBL
  ENSSSCT00030051400.1 UniProtKB/TrEMBL
  ENSSSCT00035066626.1 UniProtKB/TrEMBL
  ENSSSCT00040096203.1 UniProtKB/TrEMBL
  ENSSSCT00050107598.1 UniProtKB/TrEMBL
  ENSSSCT00065088938.1 UniProtKB/TrEMBL
  ENSSSCT00070055205.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro NST/OST UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
NCBI Gene HS3ST6 ENTREZGENE
PANTHER HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 UniProtKB/TrEMBL
  PTHR10605 UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287AF31 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B1J0_PIG UniProtKB/TrEMBL
  A0A4X1VXR6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88980 ENTREZGENE