MGST3 (microsomal glutathione S-transferase 3) - Rat Genome Database

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Gene: MGST3 (microsomal glutathione S-transferase 3) Sus scrofa
Analyze
Symbol: MGST3
Name: microsomal glutathione S-transferase 3
RGD ID: 14085424
Description: ENCODES a protein that exhibits glutathione peroxidase activity (ortholog); glutathione transferase activity (ortholog); INVOLVED IN response to organonitrogen compound (ortholog); ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); intracellular membrane-bounded organelle (inferred); membrane (inferred); INTERACTS WITH aristolochic acid A; deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase 3, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,069,607 - 85,094,981 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1485,069,603 - 85,095,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,725,520 - 92,750,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:16971568   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MGST3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,069,607 - 85,094,981 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1485,069,603 - 85,095,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,725,520 - 92,750,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MGST3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,631,234 - 165,656,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,631,213 - 165,661,796 (+)EnsemblGRCh38hg38GRCh38
GRCh371165,600,471 - 165,625,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,867,074 - 163,891,481 (+)NCBINCBI36Build 36hg18NCBI36
Build 341162,332,107 - 162,356,511NCBI
Celera1138,705,621 - 138,730,025 (+)NCBICelera
Cytogenetic Map1q24.1NCBI
HuRef1136,847,571 - 136,872,857 (+)NCBIHuRef
CHM1_11167,022,686 - 167,047,957 (+)NCBICHM1_1
T2T-CHM13v2.01164,977,647 - 165,002,573 (+)NCBIT2T-CHM13v2.0
Mgst3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,199,535 - 167,221,410 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,199,535 - 167,221,410 (-)EnsemblGRCm39 Ensembl
GRCm381167,371,966 - 167,393,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,371,966 - 167,393,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,302,515 - 169,323,928 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,209,059 - 169,230,472 (-)NCBIMGSCv36mm8
Celera1169,789,931 - 169,811,361 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.76NCBI
Mgst3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,059,480 - 82,080,418 (-)NCBIGRCr8
mRatBN7.21379,526,541 - 79,547,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,526,541 - 79,547,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,156,415 - 82,177,230 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,463,504 - 83,484,105 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,701,212 - 80,722,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,601,499 - 85,622,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,601,499 - 85,622,314 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,244,188 - 90,265,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,038,049 - 83,058,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,052,236 - 83,073,033 (-)NCBI
Celera1379,231,777 - 79,252,592 (-)NCBICelera
Cytogenetic Map13q24NCBI
Mgst3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546211,024,789 - 11,031,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546211,024,678 - 11,041,851 (-)NCBIChiLan1.0ChiLan1.0
MGST3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,110,120 - 84,137,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,778,739 - 83,805,682 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01141,063,051 - 141,087,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,852,428 - 144,876,800 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,868,059 - 144,876,684 (+)Ensemblpanpan1.1panPan2
MGST3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,670,329 - 17,691,822 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,668,752 - 17,718,704 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,726,881 - 17,748,346 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,724,958 - 17,751,927 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,724,911 - 17,778,579 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,723,864 - 17,745,307 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,075,030 - 18,096,456 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,369,309 - 18,390,981 (-)NCBIUU_Cfam_GSD_1.0
Mgst3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,807,586 - 101,819,050 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,654,441 - 19,659,291 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,654,335 - 19,665,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGST3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,227,351 - 63,252,547 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,224,338 - 63,252,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605564,986,997 - 65,012,877 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgst3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248263,969,929 - 3,987,159 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248263,969,838 - 3,987,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MGST3
700 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006933   ⟹   ENSSSCP00000006744
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl485,069,607 - 85,094,981 (-)Ensembl
RefSeq Acc Id: NM_001044556   ⟹   NP_001038021
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1485,069,719 - 85,075,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005663147   ⟹   XP_005663204
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1485,069,603 - 85,095,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013996811   ⟹   XP_013852265
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1485,069,603 - 85,094,202 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005663204   ⟸   XM_005663147
- Peptide Label: isoform X1
- UniProtKB: Q2EN77 (UniProtKB/TrEMBL),   A0A4X1VE32 (UniProtKB/TrEMBL),   A0A8D0ITP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013852265   ⟸   XM_013996811
- Peptide Label: isoform X1
- UniProtKB: Q2EN77 (UniProtKB/TrEMBL),   A0A4X1VE32 (UniProtKB/TrEMBL),   A0A8D0ITP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001038021   ⟸   NM_001044556
- UniProtKB: Q2EN77 (UniProtKB/TrEMBL),   A0A4X1VE32 (UniProtKB/TrEMBL),   A0A8D0ITP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000006744   ⟸   ENSSSCT00000006933


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006325 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005019443 UniProtKB/TrEMBL
  ENSSSCG00015026594 UniProtKB/TrEMBL
  ENSSSCG00025030593 UniProtKB/TrEMBL
  ENSSSCG00030005363 UniProtKB/TrEMBL
  ENSSSCG00035039365 UniProtKB/TrEMBL
  ENSSSCG00040040746 UniProtKB/TrEMBL
  ENSSSCG00045025636 UniProtKB/TrEMBL
  ENSSSCG00050050113 UniProtKB/TrEMBL
  ENSSSCG00055008679 UniProtKB/TrEMBL
  ENSSSCG00060069029 UniProtKB/TrEMBL
  ENSSSCG00065052570 UniProtKB/TrEMBL
  ENSSSCG00070024637 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006933 ENTREZGENE
  ENSSSCT00000006933.5 UniProtKB/TrEMBL
  ENSSSCT00005030710.1 UniProtKB/TrEMBL
  ENSSSCT00005030729.1 UniProtKB/TrEMBL
  ENSSSCT00015035314.1 UniProtKB/TrEMBL
  ENSSSCT00025041566.1 UniProtKB/TrEMBL
  ENSSSCT00030007310.1 UniProtKB/TrEMBL
  ENSSSCT00035052296.1 UniProtKB/TrEMBL
  ENSSSCT00040054473.1 UniProtKB/TrEMBL
  ENSSSCT00045043687.1 UniProtKB/TrEMBL
  ENSSSCT00050068192.1 UniProtKB/TrEMBL
  ENSSSCT00055016958.1 UniProtKB/TrEMBL
  ENSSSCT00060094244.1 UniProtKB/TrEMBL
  ENSSSCT00065071978.1 UniProtKB/TrEMBL
  ENSSSCT00070049169.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/TrEMBL
InterPro MAPEG-like_dom_sf UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/TrEMBL
KEGG Report ssc:733607 UniProtKB/TrEMBL
NCBI Gene MGST3 ENTREZGENE
PANTHER MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE 3 UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/TrEMBL
Superfamily-SCOP SSF161084 UniProtKB/TrEMBL
UniProt A0A4X1VE32 ENTREZGENE
  A0A8D0ITP4 ENTREZGENE, UniProtKB/TrEMBL
  Q2EN77 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1VE32 UniProtKB/TrEMBL
VGNC ID VGNC:90204 ENTREZGENE