CA5B (carbonic anhydrase 5B) - Rat Genome Database

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Gene: CA5B (carbonic anhydrase 5B) Sus scrofa
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Symbol: CA5B
Name: carbonic anhydrase 5B
RGD ID: 14084426
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Neurodevelopmental Disorders (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN integral component of membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: carbonic anhydrase 5B, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX12,224,159 - 12,365,025 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X12,295,393 - 12,332,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,188,075 - 13,222,663 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CA5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX12,224,159 - 12,365,025 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X12,295,393 - 12,332,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,188,075 - 13,222,663 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX15,688,830 - 15,788,411 (+)EnsemblGRCh38hg38GRCh38
GRCh38X15,738,270 - 15,788,411 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,756,393 - 15,806,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,666,333 - 15,715,669 (+)NCBINCBI36hg18NCBI36
Build 34X15,516,081 - 15,562,315NCBI
CeleraX19,872,853 - 19,923,232 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,510,606 - 13,559,489 (+)NCBIHuRef
CHM1_1X15,787,366 - 15,836,721 (+)NCBICHM1_1
Car5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X162,759,818 - 162,811,006 (-)NCBIGRCm39mm39
GRCm39 EnsemblX162,759,818 - 162,810,993 (-)Ensembl
GRCm38X163,976,822 - 164,028,010 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX163,976,822 - 164,027,997 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X160,414,754 - 160,465,942 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X159,323,196 - 159,372,102 (-)NCBImm8
CeleraX147,196,469 - 147,247,766 (-)NCBICelera
Cytogenetic MapXF5NCBI
Ca5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X30,474,697 - 30,534,797 (+)NCBI
Rnor_6.0 EnsemblX32,232,142 - 32,292,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X32,232,106 - 32,291,124 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X32,597,409 - 32,652,981 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X51,241,437 - 51,290,433 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX30,830,281 - 30,876,988 (+)NCBICelera
Cytogenetic MapXq14NCBI
Ca5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555192,412,289 - 2,455,280 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555192,415,722 - 2,455,052 (-)NCBIChiLan1.0ChiLan1.0
CA5B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X15,629,967 - 15,678,112 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX15,658,816 - 15,764,323 (+)NCBIpanpan1.1panPan2
Mhudiblu_PPA_v0X8,325,881 - 8,410,506 (+)NCBIMhudiblu_PPA_v0panPan3
CA5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X11,908,426 - 12,042,327 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX11,930,884 - 12,040,221 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX11,809,477 - 11,892,620 (+)NCBI
ROS_Cfam_1.0X11,869,327 - 12,003,333 (+)NCBI
UMICH_Zoey_3.1X11,932,374 - 12,072,571 (+)NCBI
UNSW_CanFamBas_1.0X11,926,678 - 12,059,951 (+)NCBI
UU_Cfam_GSD_1.0X11,951,875 - 12,085,347 (+)NCBI
Ca5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X5,184,444 - 5,230,212 (+)NCBI
SpeTri2.0NW_0049364705,184,489 - 5,227,855 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA5B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X14,197,561 - 14,240,294 (+)NCBI
ChlSab1.1 EnsemblX14,197,651 - 14,243,626 (+)Ensembl
Ca5b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624829455,731 - 572,603 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 7 2 3 5 1 22 2 3 3
Below cutoff 3 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013280   ⟹   ENSSSCP00000012924
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX12,224,159 - 12,365,025 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000033163   ⟹   ENSSSCP00000050715
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX12,229,913 - 12,365,025 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000091410   ⟹   ENSSSCP00000061117
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX12,312,714 - 12,365,025 (+)Ensembl
RefSeq Acc Id: XM_005673450   ⟹   XP_005673507
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X12,295,393 - 12,332,283 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021080138   ⟹   XP_020935797
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X12,296,958 - 12,332,283 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005673507 (Get FASTA)   NCBI Sequence Viewer  
  XP_020935797 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005673507   ⟸   XM_005673450
- UniProtKB: F1SQS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020935797   ⟸   XM_021080138
- Sequence:
RefSeq Acc Id: ENSSSCP00000061117   ⟸   ENSSSCT00000091410
RefSeq Acc Id: ENSSSCP00000012924   ⟸   ENSSSCT00000013280
RefSeq Acc Id: ENSSSCP00000050715   ⟸   ENSSSCT00000033163
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012141 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012924 UniProtKB/TrEMBL
  ENSSSCP00000050715 UniProtKB/TrEMBL
  ENSSSCP00000061117 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013280 UniProtKB/TrEMBL
  ENSSSCT00000033163 UniProtKB/TrEMBL
  ENSSSCT00000091410 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA-VB_mt UniProtKB/TrEMBL
  CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
KEGG Report ssc:100156418 UniProtKB/TrEMBL
NCBI Gene CA5B ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF25 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A5G2QAS0_PIG UniProtKB/TrEMBL
  F1SQS9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1SQS8 UniProtKB/TrEMBL
VGNC ID VGNC:86102 ENTREZGENE