TRIOBP (TRIO and F-actin binding protein) - Rat Genome Database

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Gene: TRIOBP (TRIO and F-actin binding protein) Sus scrofa
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Symbol: TRIOBP
Name: TRIO and F-actin binding protein
RGD ID: 14080350
Description: ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); auditory receptor cell stereocilium organization (ortholog); positive regulation of substrate adhesion-dependent cell spreading (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 28 (ortholog); FOUND IN cuticular plate (ortholog); stereocilium (ortholog); stereocilium base (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TRIO and F-actin-binding protein; TRIO and F-actin-binding protein pseudogene
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,066,086 - 10,126,491 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,066,080 - 10,132,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,561,822 - 7,597,543 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TRIOBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,066,086 - 10,126,491 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,066,080 - 10,132,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,561,822 - 7,597,543 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIOBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,697,048 - 37,776,556 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,697,048 - 37,776,556 (+)EnsemblGRCh38hg38GRCh38
GRCh372238,093,055 - 38,172,563 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,423,574 - 36,502,509 (+)NCBINCBI36Build 36hg18NCBI36
Celera2221,894,838 - 21,974,375 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,059,927 - 21,139,806 (+)NCBIHuRef
CHM1_12238,051,700 - 38,131,297 (+)NCBICHM1_1
T2T-CHM13v2.02238,158,316 - 38,238,088 (+)NCBIT2T-CHM13v2.0
Triobp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,831,924 - 78,890,069 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,831,924 - 78,890,069 (+)EnsemblGRCm39 Ensembl
GRCm381578,947,724 - 79,005,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,947,724 - 79,005,869 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,778,154 - 78,836,299 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,774,979 - 78,833,124 (+)NCBIMGSCv36mm8
Celera1581,078,111 - 81,107,504 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Triobp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,386,371 - 112,452,130 (+)NCBIGRCr8
mRatBN7.27110,505,916 - 110,569,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,506,248 - 110,562,474 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,287,666 - 112,311,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,511,189 - 114,535,390 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,479,768 - 114,504,098 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,173,892 - 120,237,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,176,530 - 120,230,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,168,221 - 120,228,826 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,917,008 - 116,969,695 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,980,831 - 116,993,049 (+)NCBI
Celera7106,842,713 - 106,896,626 (+)NCBICelera
Cytogenetic Map7q34NCBI
TRIOBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,554,490 - 47,636,527 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,242,516 - 50,326,567 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,662,794 - 18,693,138 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,487,338 - 36,524,404 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,451,860 - 36,522,391 (+)Ensemblpanpan1.1panPan2
TRIOBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,856,981 - 26,913,330 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,857,678 - 26,911,083 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,811,904 - 26,834,990 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,648,784 - 27,671,889 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11027,371,705 - 27,394,760 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,680,414 - 27,703,444 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,857,643 - 27,880,686 (-)NCBIUU_Cfam_GSD_1.0
Triobp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,327,377 - 10,380,012 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364923,337,791 - 3,390,420 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIOBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,447,340 - 20,476,669 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,344,581 - 105,372,614 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Triobp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475210,130,857 - 10,186,242 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRIOBP
2490 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 21 2 3 3
Below cutoff 2

Sequence


RefSeq Acc Id: ENSSSCT00000024579   ⟹   ENSSSCP00000024566
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,066,086 - 10,095,502 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000052648   ⟹   ENSSSCP00000044429
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,066,086 - 10,094,743 (-)Ensembl
RefSeq Acc Id: XM_013997526   ⟹   XP_013852980
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1510,066,080 - 10,095,318 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013997529   ⟹   XP_013852983
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1510,081,249 - 10,095,318 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091502   ⟹   XP_020947161
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1510,066,080 - 10,132,668 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020947161   ⟸   XM_021091502
- Peptide Label: isoform X1
- UniProtKB: A0A8D1IBP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013852980   ⟸   XM_013997526
- Peptide Label: isoform X2
- UniProtKB: I3LKF2 (UniProtKB/TrEMBL),   A0A8D1NQN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013852983   ⟸   XM_013997529
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSSSCP00000024566   ⟸   ENSSSCT00000024579
RefSeq Acc Id: ENSSSCP00000044429   ⟸   ENSSSCT00000052648
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000020777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00045026001 UniProtKB/TrEMBL
  ENSSSCG00050068923 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024579 ENTREZGENE
  ENSSSCT00000024579.4 UniProtKB/TrEMBL
  ENSSSCT00000052648.3 UniProtKB/TrEMBL
  ENSSSCT00045044698.1 UniProtKB/TrEMBL
  ENSSSCT00050094061.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro M-RIP_PH UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report ssc:100516320 UniProtKB/TrEMBL
NCBI Gene TRIOBP ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  TRIO AND F-ACTIN-BINDING PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A287AK89_PIG UniProtKB/TrEMBL
  A0A8D1IBP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1NQN5 ENTREZGENE, UniProtKB/TrEMBL
  I3LKF2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:112557 ENTREZGENE