TRAM1 (translocation associated membrane protein 1) - Rat Genome Database

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Gene: TRAM1 (translocation associated membrane protein 1) Sus scrofa
Analyze
Symbol: TRAM1
Name: translocation associated membrane protein 1
RGD ID: 14076238
Description: INVOLVED IN cotranslational protein targeting to membrane (inferred); protein insertion into ER membrane (inferred); protein transport (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: translocating chain-associated membrane protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl464,768,698 - 64,800,508 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1464,768,600 - 64,800,513 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2470,399,155 - 70,431,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl464,768,698 - 64,800,508 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1464,768,600 - 64,800,513 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2470,399,155 - 70,431,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38870,573,218 - 70,608,416 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl870,573,218 - 70,608,416 (-)EnsemblGRCh38hg38GRCh38
GRCh37871,485,453 - 71,520,651 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,648,227 - 71,683,158 (-)NCBINCBI36Build 36hg18NCBI36
Build 34871,648,226 - 71,683,158NCBI
Celera867,483,078 - 67,518,322 (-)NCBICelera
Cytogenetic Map8q13.3NCBI
HuRef866,978,304 - 67,013,532 (-)NCBIHuRef
CHM1_1871,541,019 - 71,576,230 (-)NCBICHM1_1
T2T-CHM13v2.0871,003,150 - 71,038,323 (-)NCBIT2T-CHM13v2.0
Tram1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,634,917 - 13,660,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,634,922 - 13,660,134 (-)EnsemblGRCm39 Ensembl
GRCm38113,564,693 - 13,589,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,564,698 - 13,589,910 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,554,783 - 13,579,945 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,549,916 - 13,575,078 (-)NCBIMGSCv36mm8
Celera113,514,581 - 13,539,714 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.18NCBI
Tram1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8510,425,710 - 10,450,669 (+)NCBIGRCr8
mRatBN7.255,642,579 - 5,667,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl55,642,546 - 5,686,971 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx57,780,736 - 7,805,759 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.059,419,625 - 9,444,647 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.059,110,778 - 9,135,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.055,215,196 - 5,297,337 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl55,215,196 - 5,316,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0510,062,171 - 10,062,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0510,121,579 - 10,138,210 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.454,844,208 - 4,869,207 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.154,844,207 - 4,869,206 (+)NCBI
Celera55,235,381 - 5,252,006 (+)NCBICelera
Cytogenetic Map5q11NCBI
Tram1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554449,110,807 - 9,152,125 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554449,110,533 - 9,153,585 (+)NCBIChiLan1.0ChiLan1.0
TRAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2786,306,766 - 86,342,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1861,936,216 - 61,972,011 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0867,098,588 - 67,133,511 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1868,759,038 - 68,793,750 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl868,759,040 - 68,794,303 (-)Ensemblpanpan1.1panPan2
TRAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12919,669,622 - 19,703,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2919,669,628 - 19,703,669 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2919,929,189 - 19,963,216 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02919,766,644 - 19,800,987 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2919,766,644 - 19,800,983 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12919,804,740 - 19,838,512 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02919,871,008 - 19,905,124 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02920,151,950 - 20,186,017 (-)NCBIUU_Cfam_GSD_1.0
Tram1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530359,528,340 - 59,551,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649615,233,631 - 15,257,140 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649615,233,692 - 15,257,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1866,312,103 - 66,344,738 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl866,311,614 - 66,344,840 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603975,081,633 - 75,114,264 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tram1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,619,043 - 20,653,438 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,618,963 - 20,653,285 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRAM1
642 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 3 5 1 3 2 3 3
Low 1 2 1 20
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006787   ⟹   ENSSSCP00000006603
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl464,749,244 - 64,836,126 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000038996   ⟹   ENSSSCP00000054555
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl464,768,732 - 64,800,508 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000044817   ⟹   ENSSSCP00000049115
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl464,768,698 - 64,800,507 (+)Ensembl
RefSeq Acc Id: XM_001924618   ⟹   XP_001924653
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1464,768,600 - 64,800,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013988065   ⟹   XP_013843519
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1464,768,685 - 64,800,513 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001924653   ⟸   XM_001924618
- Peptide Label: isoform X1
- UniProtKB: A0A4X1UPH2 (UniProtKB/TrEMBL),   A0A481D5U0 (UniProtKB/TrEMBL),   A0A287AY88 (UniProtKB/TrEMBL),   A0A8D0WCK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013843519   ⟸   XM_013988065
- Peptide Label: isoform X2
- UniProtKB: A0A287AY88 (UniProtKB/TrEMBL),   A0A8D0WCK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000049115   ⟸   ENSSSCT00000044817
RefSeq Acc Id: ENSSSCP00000006603   ⟸   ENSSSCT00000006787
RefSeq Acc Id: ENSSSCP00000054555   ⟸   ENSSSCT00000038996
Protein Domains
TLC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006193 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015060436 UniProtKB/TrEMBL
  ENSSSCG00025045410 UniProtKB/TrEMBL
  ENSSSCG00030028211 UniProtKB/TrEMBL
  ENSSSCG00035018824 UniProtKB/TrEMBL
  ENSSSCG00045005857 UniProtKB/TrEMBL
  ENSSSCG00050063796 UniProtKB/TrEMBL
  ENSSSCG00055024118 UniProtKB/TrEMBL
  ENSSSCG00060064876 UniProtKB/TrEMBL
  ENSSSCG00065047183 UniProtKB/TrEMBL
  ENSSSCG00070018579 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038996.3 UniProtKB/TrEMBL
  ENSSSCT00000044817 ENTREZGENE
  ENSSSCT00000044817.2 UniProtKB/TrEMBL
  ENSSSCT00015080705.1 UniProtKB/TrEMBL
  ENSSSCT00015080774.1 UniProtKB/TrEMBL
  ENSSSCT00025061677.1 UniProtKB/TrEMBL
  ENSSSCT00025061826.1 UniProtKB/TrEMBL
  ENSSSCT00025061978.1 UniProtKB/TrEMBL
  ENSSSCT00030039449.1 UniProtKB/TrEMBL
  ENSSSCT00030039456.1 UniProtKB/TrEMBL
  ENSSSCT00030039459.1 UniProtKB/TrEMBL
  ENSSSCT00035024327.1 UniProtKB/TrEMBL
  ENSSSCT00035024337.1 UniProtKB/TrEMBL
  ENSSSCT00035024342.1 UniProtKB/TrEMBL
  ENSSSCT00045009738.1 UniProtKB/TrEMBL
  ENSSSCT00045009754.1 UniProtKB/TrEMBL
  ENSSSCT00045009780.1 UniProtKB/TrEMBL
  ENSSSCT00050086865.1 UniProtKB/TrEMBL
  ENSSSCT00055047516.1 UniProtKB/TrEMBL
  ENSSSCT00055047624.1 UniProtKB/TrEMBL
  ENSSSCT00060088555.1 UniProtKB/TrEMBL
  ENSSSCT00060088576.1 UniProtKB/TrEMBL
  ENSSSCT00060088595.1 UniProtKB/TrEMBL
  ENSSSCT00065064517.1 UniProtKB/TrEMBL
  ENSSSCT00065064526.1 UniProtKB/TrEMBL
  ENSSSCT00065064529.1 UniProtKB/TrEMBL
  ENSSSCT00070036633.1 UniProtKB/TrEMBL
InterPro TLC-dom UniProtKB/TrEMBL
  Translocation_assoc_membrane UniProtKB/TrEMBL
KEGG Report ssc:100151996 UniProtKB/TrEMBL
NCBI Gene TRAM1 ENTREZGENE
PANTHER PTHR12371 UniProtKB/TrEMBL
  TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 UniProtKB/TrEMBL
Pfam TRAM_LAG1_CLN8 UniProtKB/TrEMBL
PIRSF Translocation_assoc_membrane UniProtKB/TrEMBL
PROSITE TLC UniProtKB/TrEMBL
SMART TLC UniProtKB/TrEMBL
UniProt A0A287AY88 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BDF6_PIG UniProtKB/TrEMBL
  A0A481D5U0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UPH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WCK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Z0J0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:98878 ENTREZGENE