FNIP1 (folliculin interacting protein 1) - Rat Genome Database

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Pathways
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Gene: FNIP1 (folliculin interacting protein 1) Sus scrofa
Analyze
Symbol: FNIP1
Name: folliculin interacting protein 1
RGD ID: 14067865
Description: ENCODES a protein that exhibits ATPase inhibitor activity (inferred); enzyme activator activity (inferred); enzyme binding (inferred); INVOLVED IN B cell apoptotic process (ortholog); cellular response to starvation (ortholog); immature B cell differentiation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); lysosomal membrane (inferred); INTERACTS WITH ammonia
Type: protein-coding
RefSeq Status: MODEL
Previously known as: folliculin-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2133,957,553 - 134,093,413 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12133,958,112 - 134,093,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22139,275,935 - 139,352,641 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ammonia  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IEA)
lysosomal membrane  (IEA)
lysosome  (IEA)
membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
FNIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2133,957,553 - 134,093,413 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12133,958,112 - 134,093,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22139,275,935 - 139,352,641 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FNIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385131,641,714 - 131,797,017 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5131,641,714 - 131,797,017 (-)EnsemblGRCh38hg38GRCh38
GRCh375130,977,407 - 131,132,710 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,005,306 - 131,160,655 (-)NCBINCBI36Build 36hg18NCBI36
Celera5127,107,692 - 127,262,904 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5126,169,994 - 126,325,270 (-)NCBIHuRef
CHM1_15130,410,265 - 130,565,793 (-)NCBICHM1_1
T2T-CHM13v2.05132,161,677 - 132,316,880 (-)NCBIT2T-CHM13v2.0
Fnip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,328,071 - 54,409,067 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1154,329,025 - 54,409,061 (+)EnsemblGRCm39 Ensembl
GRCm381154,438,107 - 54,518,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,438,199 - 54,518,235 (+)EnsemblGRCm38mm10GRCm38
MGSCv371154,251,681 - 54,331,743 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,281,612 - 54,361,659 (+)NCBIMGSCv36mm8
Celera1159,025,781 - 59,105,810 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.13NCBI
Fnip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81039,068,432 - 39,151,552 (+)NCBIGRCr8
mRatBN7.21038,567,728 - 38,650,824 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1038,567,729 - 38,650,824 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1043,253,258 - 43,336,564 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01042,743,339 - 42,826,641 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01038,247,053 - 38,330,353 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01039,786,687 - 39,870,188 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,559,751 - 39,642,936 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,922,276 - 39,928,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1037,908,242 - 37,991,313 (+)NCBICelera
Cytogenetic Map10q22NCBI
Fnip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554083,117,277 - 3,238,223 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554083,117,258 - 3,238,223 (-)NCBIChiLan1.0ChiLan1.0
FNIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24126,966,205 - 127,114,876 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15125,105,770 - 125,254,344 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05127,070,906 - 127,219,548 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15133,235,501 - 133,384,218 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5133,235,501 - 133,384,218 (-)Ensemblpanpan1.1panPan2
FNIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11119,979,294 - 20,134,341 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1119,979,163 - 20,134,229 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,775,252 - 18,930,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01120,756,596 - 20,912,040 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1120,757,010 - 20,911,984 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11119,484,212 - 19,639,355 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01119,331,828 - 19,486,818 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01119,972,971 - 20,128,177 (-)NCBIUU_Cfam_GSD_1.0
Fnip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213116,326,366 - 116,425,408 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366473,329,103 - 3,428,242 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366473,329,097 - 3,428,170 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12334,443,171 - 34,637,797 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2334,480,901 - 34,637,662 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603443,322,684 - 43,488,910 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fnip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473340,263,898 - 40,393,690 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473340,263,760 - 40,396,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FNIP1
2357 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 3 3 5 2 23 2 3 3
Low 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015591   ⟹   ENSSSCP00000015179
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,958,114 - 134,093,371 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000060769   ⟹   ENSSSCP00000031164
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,958,114 - 134,093,413 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091874   ⟹   ENSSSCP00000077331
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,958,116 - 134,093,362 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000096911   ⟹   ENSSSCP00000078116
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,957,553 - 134,093,364 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000098524   ⟹   ENSSSCP00000078767
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,957,553 - 134,093,364 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000104649   ⟹   ENSSSCP00000081228
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2133,958,114 - 134,093,413 (-)Ensembl
RefSeq Acc Id: XM_021085414   ⟹   XP_020941073
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12133,958,112 - 134,093,408 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085415   ⟹   XP_020941074
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12133,958,117 - 134,037,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085416   ⟹   XP_020941075
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12133,958,115 - 134,093,383 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020941073   ⟸   XM_021085414
- Peptide Label: isoform X1
- UniProtKB: A0A8W4FGW2 (UniProtKB/TrEMBL),   A0A8D0SLA0 (UniProtKB/TrEMBL),   A0A8D1YRD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941075   ⟸   XM_021085416
- Peptide Label: isoform X3
- UniProtKB: A0A8D0M651 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941074   ⟸   XM_021085415
- Peptide Label: isoform X2
- UniProtKB: A0A8D1E1U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015179   ⟸   ENSSSCT00000015591
RefSeq Acc Id: ENSSSCP00000031164   ⟸   ENSSSCT00000060769
RefSeq Acc Id: ENSSSCP00000078116   ⟸   ENSSSCT00000096911
RefSeq Acc Id: ENSSSCP00000077331   ⟸   ENSSSCT00000091874
RefSeq Acc Id: ENSSSCP00000081228   ⟸   ENSSSCT00000104649
RefSeq Acc Id: ENSSSCP00000078767   ⟸   ENSSSCT00000098524
Protein Domains
UDENN FNIP1/2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014269 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005044997 UniProtKB/TrEMBL
  ENSSSCG00015020367 UniProtKB/TrEMBL
  ENSSSCG00025051418 UniProtKB/TrEMBL
  ENSSSCG00030059649 UniProtKB/TrEMBL
  ENSSSCG00035039265 UniProtKB/TrEMBL
  ENSSSCG00040027850 UniProtKB/TrEMBL
  ENSSSCG00045010841 UniProtKB/TrEMBL
  ENSSSCG00050044786 UniProtKB/TrEMBL
  ENSSSCG00060049352 UniProtKB/TrEMBL
  ENSSSCG00065043210 UniProtKB/TrEMBL
  ENSSSCG00070018538 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015591.4 UniProtKB/TrEMBL
  ENSSSCT00000060769.3 UniProtKB/TrEMBL
  ENSSSCT00000091874.1 UniProtKB/TrEMBL
  ENSSSCT00000096911 ENTREZGENE
  ENSSSCT00000096911.1 UniProtKB/TrEMBL
  ENSSSCT00000098524.1 UniProtKB/TrEMBL
  ENSSSCT00000104649 ENTREZGENE
  ENSSSCT00000104649.1 UniProtKB/TrEMBL
  ENSSSCT00005072616.1 UniProtKB/TrEMBL
  ENSSSCT00005072656.1 UniProtKB/TrEMBL
  ENSSSCT00005072663.1 UniProtKB/TrEMBL
  ENSSSCT00005072688.1 UniProtKB/TrEMBL
  ENSSSCT00005072693.1 UniProtKB/TrEMBL
  ENSSSCT00015027021.1 UniProtKB/TrEMBL
  ENSSSCT00015027236.1 UniProtKB/TrEMBL
  ENSSSCT00015027338.1 UniProtKB/TrEMBL
  ENSSSCT00025070374.1 UniProtKB/TrEMBL
  ENSSSCT00025070577.1 UniProtKB/TrEMBL
  ENSSSCT00025070740.1 UniProtKB/TrEMBL
  ENSSSCT00030083347.1 UniProtKB/TrEMBL
  ENSSSCT00030083373.1 UniProtKB/TrEMBL
  ENSSSCT00030083420.1 UniProtKB/TrEMBL
  ENSSSCT00035052176.1 UniProtKB/TrEMBL
  ENSSSCT00035052179.1 UniProtKB/TrEMBL
  ENSSSCT00035052183.1 UniProtKB/TrEMBL
  ENSSSCT00040037354.1 UniProtKB/TrEMBL
  ENSSSCT00040037533.1 UniProtKB/TrEMBL
  ENSSSCT00040037697.1 UniProtKB/TrEMBL
  ENSSSCT00040037782.1 UniProtKB/TrEMBL
  ENSSSCT00045018434.1 UniProtKB/TrEMBL
  ENSSSCT00045018489.1 UniProtKB/TrEMBL
  ENSSSCT00045018574.1 UniProtKB/TrEMBL
  ENSSSCT00050060961.1 UniProtKB/TrEMBL
  ENSSSCT00050060965.1 UniProtKB/TrEMBL
  ENSSSCT00060067026.1 UniProtKB/TrEMBL
  ENSSSCT00060067034.1 UniProtKB/TrEMBL
  ENSSSCT00060067038.1 UniProtKB/TrEMBL
  ENSSSCT00065059182.1 UniProtKB/TrEMBL
  ENSSSCT00065059189.1 UniProtKB/TrEMBL
  ENSSSCT00065059191.1 UniProtKB/TrEMBL
  ENSSSCT00065059196.1 UniProtKB/TrEMBL
  ENSSSCT00065059217.1 UniProtKB/TrEMBL
  ENSSSCT00070036679.1 UniProtKB/TrEMBL
  ENSSSCT00070036704.1 UniProtKB/TrEMBL
  ENSSSCT00070036709.1 UniProtKB/TrEMBL
InterPro DENN_FNIP1/2 UniProtKB/TrEMBL
  FNIP_C_dom UniProtKB/TrEMBL
  FNIP_fam UniProtKB/TrEMBL
  FNIP_mid_dom UniProtKB/TrEMBL
  FNIP_N_dom UniProtKB/TrEMBL
NCBI Gene FNIP1 ENTREZGENE
PANTHER FOLLICULIN-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam FNIP_C UniProtKB/TrEMBL
  FNIP_M UniProtKB/TrEMBL
  FNIP_N UniProtKB/TrEMBL
PRINTS FOLLICULNIP1 UniProtKB/TrEMBL
PROSITE DENN_FNIP12 UniProtKB/TrEMBL
UniProt A0A286ZI35_PIG UniProtKB/TrEMBL
  A0A4X1UN05_PIG UniProtKB/TrEMBL
  A0A4X1UPM6_PIG UniProtKB/TrEMBL
  A0A4X1UR38_PIG UniProtKB/TrEMBL
  A0A8D0M5L2_PIG UniProtKB/TrEMBL
  A0A8D0M651 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MZ66_PIG UniProtKB/TrEMBL
  A0A8D0SLA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TRV6_PIG UniProtKB/TrEMBL
  A0A8D0ZSM8_PIG UniProtKB/TrEMBL
  A0A8D0ZXD5_PIG UniProtKB/TrEMBL
  A0A8D1CUB5_PIG UniProtKB/TrEMBL
  A0A8D1E1U7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1E225_PIG UniProtKB/TrEMBL
  A0A8D1E3R3_PIG UniProtKB/TrEMBL
  A0A8D1H626_PIG UniProtKB/TrEMBL
  A0A8D1YRD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FDK0_PIG UniProtKB/TrEMBL
  A0A8W4FGW2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FHQ8_PIG UniProtKB/TrEMBL
  A0A8W4FPU5_PIG UniProtKB/TrEMBL
  F1RJW1_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88187 ENTREZGENE