FGFR4 (fibroblast growth factor receptor 4) - Rat Genome Database

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Gene: FGFR4 (fibroblast growth factor receptor 4) Sus scrofa
Analyze
Symbol: FGFR4
Name: fibroblast growth factor receptor 4
RGD ID: 14064683
Description: ENCODES a protein that exhibits ATP binding (inferred); fibroblast growth factor binding (inferred); fibroblast growth factor receptor activity (inferred); INVOLVED IN alveolar secondary septum development (ortholog); cholesterol homeostasis (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); adult respiratory distress syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN cell-cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl280,841,536 - 80,853,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1280,841,536 - 80,853,791 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2282,414,997 - 82,427,239 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:17055567  


Genomics

Comparative Map Data
FGFR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl280,841,536 - 80,853,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1280,841,536 - 80,853,791 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2282,414,997 - 82,427,239 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGFR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385177,086,915 - 177,098,144 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5177,086,905 - 177,098,144 (+)EnsemblGRCh38hg38GRCh38
GRCh375176,513,916 - 176,525,145 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,446,527 - 176,457,733 (+)NCBINCBI36hg18NCBI36
Build 345176,446,526 - 176,457,730NCBI
Celera5171,976,184 - 171,987,401 (-)NCBI
Cytogenetic Map5q35.2NCBI
HuRef5171,435,609 - 171,446,679 (+)NCBIHuRef
CHM1_15175,946,753 - 175,957,892 (+)NCBICHM1_1
T2T-CHM13v2.05177,630,123 - 177,641,352 (+)NCBI
Fgfr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,300,631 - 55,316,572 (+)NCBIGRCm39mm39
GRCm39 Ensembl1355,300,453 - 55,316,572 (+)Ensembl
GRCm381355,152,818 - 55,168,759 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,152,640 - 55,168,759 (+)EnsemblGRCm38mm10GRCm38
MGSCv371355,254,179 - 55,270,120 (+)NCBIGRCm37mm9NCBIm37
MGSCv361355,162,497 - 55,178,362 (+)NCBImm8
Celera1356,213,486 - 56,229,296 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1329.8NCBI
Fgfr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,461,541 - 9,476,268 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl179,461,547 - 9,476,242 (-)Ensembl
Rnor_6.0179,990,072 - 10,004,339 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,990,078 - 10,004,321 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,099,383 - 12,113,637 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,512,144 - 15,527,348 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,512,146 - 15,523,432 (-)NCBI
Celera179,540,006 - 9,554,750 (-)NCBICelera
Cytogenetic Map17p14NCBI
Fgfr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,370,468 - 29,383,971 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540829,370,480 - 29,383,531 (+)NCBIChiLan1.0ChiLan1.0
FGFR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15179,454,995 - 179,466,114 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5179,454,995 - 179,467,605 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05172,386,443 - 172,400,271 (+)NCBIMhudiblu_PPA_v0panPan3
FGFR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,243,689 - 36,254,636 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,244,220 - 36,252,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha436,209,722 - 36,220,671 (-)NCBI
ROS_Cfam_1.0436,607,886 - 36,618,835 (-)NCBI
ROS_Cfam_1.0 Ensembl436,607,906 - 36,618,801 (-)Ensembl
UMICH_Zoey_3.1436,434,871 - 36,445,815 (-)NCBI
UNSW_CanFamBas_1.0436,622,022 - 36,632,969 (-)NCBI
UU_Cfam_GSD_1.0437,130,265 - 37,141,210 (-)NCBI
Fgfr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213122,360,727 - 122,372,869 (+)NCBI
SpeTri2.0NW_0049365971,388,394 - 1,397,731 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGFR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12379,095,031 - 79,106,018 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2379,097,429 - 79,105,456 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607510,259,717 - 10,291,447 (+)NCBIVero_WHO_p1.0
Fgfr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473312,964,746 - 12,976,732 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473312,964,893 - 12,979,198 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1
Low 8 2 13 1 1
Below cutoff 1 3 3 5 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000035375   ⟹   ENSSSCP00000030615
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl280,841,540 - 80,853,792 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000036577   ⟹   ENSSSCP00000030959
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl280,841,536 - 80,853,796 (-)Ensembl
RefSeq Acc Id: XM_003123682   ⟹   XP_003123730
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1280,841,536 - 80,853,791 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987555   ⟹   XP_013843009
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1280,841,536 - 80,853,787 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003123730 (Get FASTA)   NCBI Sequence Viewer  
  XP_013843009 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC77496 (Get FASTA)   NCBI Sequence Viewer  
  CAO86063 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003123730   ⟸   XM_003123682
- Sequence:
RefSeq Acc Id: XP_013843009   ⟸   XM_013987555
- Sequence:
RefSeq Acc Id: ENSSSCP00000030615   ⟸   ENSSSCT00000035375
RefSeq Acc Id: ENSSSCP00000030959   ⟸   ENSSSCT00000036577
Protein Domains
Ig-like   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014047 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005010102 UniProtKB/TrEMBL
  ENSSSCG00015023107 UniProtKB/TrEMBL
  ENSSSCG00025069572 UniProtKB/TrEMBL
  ENSSSCG00030032534 UniProtKB/TrEMBL
  ENSSSCG00035024891 UniProtKB/TrEMBL
  ENSSSCG00040057885 UniProtKB/TrEMBL
  ENSSSCG00045036580 UniProtKB/TrEMBL
  ENSSSCG00050008451 UniProtKB/TrEMBL
  ENSSSCG00055016172 UniProtKB/TrEMBL
  ENSSSCG00060076639 UniProtKB/TrEMBL
  ENSSSCG00065066871 UniProtKB/TrEMBL
  ENSSSCG00070000643 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000030615 UniProtKB/TrEMBL
  ENSSSCP00000030959 UniProtKB/TrEMBL
  ENSSSCP00005009549 UniProtKB/TrEMBL
  ENSSSCP00015012126 UniProtKB/TrEMBL
  ENSSSCP00015012191 UniProtKB/TrEMBL
  ENSSSCP00025041962 UniProtKB/TrEMBL
  ENSSSCP00025042069 UniProtKB/TrEMBL
  ENSSSCP00030020201 UniProtKB/TrEMBL
  ENSSSCP00030020211 UniProtKB/TrEMBL
  ENSSSCP00035012888 UniProtKB/TrEMBL
  ENSSSCP00035012893 UniProtKB/TrEMBL
  ENSSSCP00040033864 UniProtKB/TrEMBL
  ENSSSCP00040033942 UniProtKB/TrEMBL
  ENSSSCP00045044381 UniProtKB/TrEMBL
  ENSSSCP00045044468 UniProtKB/TrEMBL
  ENSSSCP00050004869 UniProtKB/TrEMBL
  ENSSSCP00050004878 UniProtKB/TrEMBL
  ENSSSCP00055025363 UniProtKB/TrEMBL
  ENSSSCP00055025482 UniProtKB/TrEMBL
  ENSSSCP00060046166 UniProtKB/TrEMBL
  ENSSSCP00060046215 UniProtKB/TrEMBL
  ENSSSCP00065040177 UniProtKB/TrEMBL
  ENSSSCP00070001077 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000035375 UniProtKB/TrEMBL
  ENSSSCT00000036577 UniProtKB/TrEMBL
  ENSSSCT00005015985 UniProtKB/TrEMBL
  ENSSSCT00015030630 UniProtKB/TrEMBL
  ENSSSCT00015030803 UniProtKB/TrEMBL
  ENSSSCT00025095590 UniProtKB/TrEMBL
  ENSSSCT00025095827 UniProtKB/TrEMBL
  ENSSSCT00030044969 UniProtKB/TrEMBL
  ENSSSCT00030044998 UniProtKB/TrEMBL
  ENSSSCT00035032730 UniProtKB/TrEMBL
  ENSSSCT00035032738 UniProtKB/TrEMBL
  ENSSSCT00040078501 UniProtKB/TrEMBL
  ENSSSCT00040078664 UniProtKB/TrEMBL
  ENSSSCT00045062972 UniProtKB/TrEMBL
  ENSSSCT00045063083 UniProtKB/TrEMBL
  ENSSSCT00050011476 UniProtKB/TrEMBL
  ENSSSCT00050011512 UniProtKB/TrEMBL
  ENSSSCT00055031865 UniProtKB/TrEMBL
  ENSSSCT00055032004 UniProtKB/TrEMBL
  ENSSSCT00060105180 UniProtKB/TrEMBL
  ENSSSCT00060105253 UniProtKB/TrEMBL
  ENSSSCT00065091784 UniProtKB/TrEMBL
  ENSSSCT00070001226 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FGF_rcpt_fam UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
KEGG Report ssc:100127133 UniProtKB/TrEMBL
NCBI Gene FGFR4 ENTREZGENE
Pfam I-set UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
PIRSF FGFR UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A4X1SFS2_PIG UniProtKB/TrEMBL
  A0A8D0LHQ6_PIG UniProtKB/TrEMBL
  A0A8D0T620_PIG UniProtKB/TrEMBL
  A0A8D0WHH3_PIG UniProtKB/TrEMBL
  A0A8D1WWP5_PIG UniProtKB/TrEMBL
  A7MAE4_PIG UniProtKB/TrEMBL
  F1S3B8_PIG UniProtKB/TrEMBL
  K7GRT5_PIG UniProtKB/TrEMBL
  O18918_PIG UniProtKB/TrEMBL
UniProt Secondary A0A480WPL5 UniProtKB/TrEMBL
VGNC ID VGNC:88120 ENTREZGENE