SAXO1 (stabilizer of axonemal microtubules 1)

Gene: SAXO1 (stabilizer of axonemal microtubules 1) Sus scrofa

Analyze

Symbol:

SAXO1

Name:

stabilizer of axonemal microtubules 1

RGD ID:

14064513

Description:

ENCODES a protein that exhibits microtubule binding (inferred); INVOLVED IN cellular response to cold (inferred); cold acclimation (inferred); positive regulation of cilium assembly (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN axonemal microtubule (inferred); centriole (inferred); ciliary basal body (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	203,788,341 - 203,923,516 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	203,788,322 - 203,923,889 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to cold (IEA)

cold acclimation (IEA)

positive regulation of cilium assembly (IEA)

protein stabilization (IEA)

Cellular Component

axonemal microtubule (IBA,IEA)

centriole (IBA,IEA)

ciliary basal body (IBA,IEA)

cytoskeleton (IBA,IEA)

motile cilium (IEA)

sperm flagellum (IBA,IEA)

Molecular Function

microtubule binding (IBA,IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SAXO1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	203,788,341 - 203,923,516 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	203,788,322 - 203,923,889 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SAXO1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	18,927,650 - 19,049,339 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	18,858,906 - 19,049,358 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	18,927,648 - 19,049,337 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	18,917,893 - 19,023,184 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	18,917,892 - 19,023,184	NCBI
Celera	9	18,854,088 - 18,959,450 (-)	NCBI		Celera
Cytogenetic Map	9	p22.1	NCBI
HuRef	9	18,889,549 - 18,994,879 (-)	NCBI		HuRef
CHM1_1	9	18,927,885 - 19,033,250 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	18,940,631 - 19,062,204 (-)	NCBI		T2T-CHM13v2.0

Saxo1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	86,362,662 - 86,476,540 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	86,362,878 - 86,476,565 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	86,444,425 - 86,558,303 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	86,444,641 - 86,558,328 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	86,090,602 - 86,204,207 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	85,915,929 - 86,029,561 (-)	NCBI		MGSCv36	mm8
Celera	4	84,960,048 - 85,073,131 (-)	NCBI		Celera
Cytogenetic Map	4	C4	NCBI
cM Map	4	40.69	NCBI

Saxo1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	105,982,949 - 106,139,298 (-)	NCBI		GRCr8
mRatBN7.2	5	100,937,134 - 101,093,308 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	100,937,130 - 101,093,281 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	104,771,081 - 104,921,001 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	104,771,392 - 104,920,906 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	108,756,769 - 108,908,811 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	105,443,094 - 105,589,653 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	99,430,281 - 99,578,228 (-)	NCBI		Celera
Cytogenetic Map	5	q31	NCBI

Saxo1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	21,414,033 - 21,494,399 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	21,414,937 - 21,454,901 (-)	NCBI	ChiLan1.0	ChiLan1.0

SAXO1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	105,503,056 - 105,740,158 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	105,509,000 - 105,620,800 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	18,741,406 - 18,868,726 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	19,234,977 - 19,346,886 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	19,234,977 - 19,346,886 (-)	Ensembl	panpan1.1		panPan2

SAXO1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	38,771,201 - 38,873,442 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	38,771,209 - 38,871,709 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	37,430,159 - 37,532,190 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	39,704,270 - 39,806,475 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	39,704,233 - 39,805,060 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	38,397,934 - 38,499,754 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	38,192,582 - 38,294,769 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	38,829,428 - 38,931,733 (-)	NCBI		UU_Cfam_GSD_1.0

Saxo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	153,215,697 - 153,313,168 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936652	885,616 - 915,113 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SAXO1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	60,671,508 - 60,788,923 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	60,766,059 - 60,788,518 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	48,796,820 - 48,914,658 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Saxo1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	22,926,686 - 22,958,800 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	22,926,420 - 23,035,788 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SAXO1
4099 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021063236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000055804 ⟹ ENSSSCP00000033066

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	1	203,788,341 - 203,923,514 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000077400 ⟹ ENSSSCP00000062000

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	1	203,788,341 - 203,923,516 (+)	Ensembl

RefSeq Acc Id:

XM_021063236 ⟹ XP_020918895

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	1	203,788,322 - 203,923,889 (+)	NCBI

Sequence:

show sequence

TAGGCGGGTGCGTGGGTGGGGCGGGCTCAGGCGGGGGCGGCGTGTGCAGGGGGAAGTTGCCAGG
GCTGCGAGGTCCACGCTTGGTGCTGCTCTCGCGCAAGGCCAGCTCAGGGACGGAAGCGGAAGAC
CGGAGTTTGCAAAGGGCCACTTAACTTTTCCTGGGAGGCAGGATTCCGAACCTTGGCCAAGGCC
CTTAAGAATTGGCGTGTTACCTGCGAGGTGGACGGGGTCTAGGCGGCAACCATGGGGGGGATGC
TCAGCGCGGACCTCCAGGCCTCGGTATGACTCCGGTGAAGAGGAAGTGCATCTGCGAGCTGTGC
TCCTGTGGGCGACATCATTGTCCACATCTCCCTACCAAGATTTATGATAAAACAGAGAAACCAT
GTCTTCTCTCCGAATATACAGAGAACTACCCTCTTTATCACTCTTACCTGCCCAGAGAGTCCTT
CAAGCCCAAGCTGGAGTACCAGAAAGGGTGCACACCAATGGAAGGCCTGACCACATCGAGGAGA
GATTTTGGGCCTCACAAAGTGTTACCAGTGAAGATCCATCAGCCTGACCAGTTCGTCTCAAGTG
GAGAGACTATGGATCTGCTCACAACATATAAGCAAGATTACAACCCCTACCCTGTCTGCCGAGT
GGACCCCATCAAACCTCGGGACAGTAAATATCCATGTGGTGACAAGATGGAGTGTCTGCCTACT
TATAAAGCTGATTATTTACCCTGGAACCAACCAAGACGAGAACTGCTTTGTCCACCACACAACT
ACCGGCCGACATCAACCAAGTTTGATAGTCGAACCACACACCAGGATGACTACTCCATGAAGGG
CCTAGTGAATACCACGAGCTGTAAGCCTCTGGCCATGCCCAAACTCTGTAACATCCCCCTGGAG
GATCTGACTAACTACAAGATGAGCTACATAGCCCACCCTATGGAGAAACGCTTTGTGTATGAGC
CGGAGAAGTTCAGACCCTGTGAAATCCCCTTTGAAAACCTCACCACCCACAAAGAGTCATACAG
GGGCCTGATGGGAGAGCCAGCCAAGAGCTTGAAACCTCCAGTCAGGCCTGGTGGGCTAGACACA
CCTTTCNTTACCACCACCGAGTTTCGAGATAAATACCAAGCCTGGCCAACACCCCAGATGTTCT
CCAAAGCTCCTGCCACCTATGTCCCTCCTGAAGAAAAGATGGACCTTATGACAACAGCGCAGGC
CCATTACACGTACCCTAAGGGTGGCCCAGCTCAGTCCTGCAGACCGGTGCTCTCCGTCAAGAAG
GGTGGCCGCTTCGAAAGCTCCACCACGACCAAAGATGACTACAAGCAGTGGGTCAGCATGCGCA
CAGAGCCACTCAGGCCCATCCCCCAGCTGAACCTTCCCACTGAGCCCTTGGACTGCCTGACCAC
CACTCGAGCCCACTATGTGCCCCACCCACCCATGGCTACCAAAAGTTTTAAGCCCTCCTTGTCT
GGCCCCCGAGGAAATATCCCTCTGGAGGGCCAGACCACATACACCATCAGCTTCACGCCCAAGG
AAGTGAGCAGGTGCCTGGCTTCATATCCCGAACCCCCTGGCTACATCTTTGAGGAAACAGATGC
TTTGGGGCATAGAATATACAGGCCAGTTTCCCAGATAGGCTCTCAGGGAAGCAGCCGTCTTTCT
CTAGGAGATCCGAAAAATCCCAACCATCAAGAGTTGGCTGTGTCAGCTTGATTTTTAACAGTTG
TACTTTAAAAATTGCACAATACTTTTAAAAGCAGATGATTGAGTTATTCATTGGACAAAAAAAG
AATTCCCCAAAATGAAAAAAACCCCCTTCATCATCATTTCCAGGACACTTGAATAAAATGAGAA
TCACTTGACTCAAGGAAAATGACTTTTAATCACTGGCTAATTAGTCCCCTTACCCCTCCCTCTG
CTGTCGGTCCCTCTTGGGTCCTTTACCTTGTGCTCATGGAATCAAAGCTGGTTTCTGAGGTTTT
GCCCCATCTGGATGTATTTTATTAATTTAATCATTGTATGCATTGACATTATGATTAACCCTTG
CCAAGCATGAAGTGCCACAGAATAAACTTTATTCTGGTGGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020918895	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000033066
	ENSSSCP00000033066.2
	ENSSSCP00000062000.1
	ENSSSCP00025013885.1
	ENSSSCP00030040843.1
	ENSSSCP00040004636.1

RefSeq Acc Id:

XP_020918895 ⟸ XM_021063236

- UniProtKB:

A0A286ZNM0 (UniProtKB/TrEMBL), A0A8D1DC59 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTPVKRKCICELCSCGRHHCPHLPTKIYDKTEKPCLLSEYTENYPLYHSYLPRESFKPKLEYQK
GCTPMEGLTTSRRDFGPHKVLPVKIHQPDQFVSSGETMDLLTTYKQDYNPYPVCRVDPIKPRDS
KYPCGDKMECLPTYKADYLPWNQPRRELLCPPHNYRPTSTKFDSRTTHQDDYSMKGLVNTTSCK
PLAMPKLCNIPLEDLTNYKMSYIAHPMEKRFVYEPEKFRPCEIPFENLTTHKESYRGLMGEPAK
SLKPPVRPGGLDTPFXTTTEFRDKYQAWPTPQMFSKAPATYVPPEEKMDLMTTAQAHYTYPKGG
PAQSCRPVLSVKKGGRFESSTTTKDDYKQWVSMRTEPLRPIPQLNLPTEPLDCLTTTRAHYVPH
PPMATKSFKPSLSGPRGNIPLEGQTTYTISFTPKEVSRCLASYPEPPGYIFEETDALGHRIYRP
VSQIGSQGSSRLSLGDPKNPNHQELAVSA

hide sequence

RefSeq Acc Id:

ENSSSCP00000033066 ⟸ ENSSSCT00000055804

RefSeq Acc Id:

ENSSSCP00000062000 ⟸ ENSSSCT00000077400

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000040408	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025024651	UniProtKB/TrEMBL
	ENSSSCG00030063176	UniProtKB/TrEMBL
	ENSSSCG00040009555	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000055804	ENTREZGENE
	ENSSSCT00000055804.3	UniProtKB/TrEMBL
	ENSSSCT00000077400.2	UniProtKB/TrEMBL
	ENSSSCT00025033327.1	UniProtKB/TrEMBL
	ENSSSCT00030088393.1	UniProtKB/TrEMBL
	ENSSSCT00040012363.1	UniProtKB/TrEMBL
InterPro	SAXO1/2	UniProtKB/TrEMBL
NCBI Gene	SAXO1	ENTREZGENE
PANTHER	PTHR31516	UniProtKB/TrEMBL
	STABILIZER OF AXONEMAL MICROTUBULES 1	UniProtKB/TrEMBL
Pfam	SAXO1-2	UniProtKB/TrEMBL
UniProt	A0A286ZNM0	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QD00_PIG	UniProtKB/TrEMBL
	A0A8D1DC59	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:92589	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar