VIPR2 (vasoactive intestinal peptide receptor 2) - Rat Genome Database

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Gene: VIPR2 (vasoactive intestinal peptide receptor 2) Sus scrofa
Analyze
Symbol: VIPR2
Name: vasoactive intestinal peptide receptor 2
RGD ID: 14059858
Description: ENCODES a protein that exhibits vasoactive intestinal polypeptide receptor activity (ortholog); INVOLVED IN activation of adenylate cyclase activity (ortholog); negative regulation of smooth muscle cell proliferation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); colitis (ortholog); schizophrenia (ortholog); FOUND IN integral component of membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: vasoactive intestinal polypeptide receptor 2; vasoactive intestinal polypeptide receptor 2 variant 1; VPAC2R
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18396,263 - 518,102 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118396,379 - 466,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218663,352 - 732,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:24520933   PMID:33388613  


Genomics

Comparative Map Data
VIPR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18396,263 - 518,102 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118396,379 - 466,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218663,352 - 732,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VIPR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7159,028,175 - 159,144,867 (-)EnsemblGRCh38hg38GRCh38
GRCh387159,028,175 - 159,144,957 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377158,820,866 - 158,937,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367158,513,627 - 158,630,410 (-)NCBINCBI36hg18NCBI36
Build 347158,320,342 - 158,437,125NCBI
Celera7153,254,268 - 153,370,389 (-)NCBI
Cytogenetic Map7q36.3NCBI
HuRef7152,560,564 - 152,677,411 (-)NCBIHuRef
CHM1_17158,828,828 - 158,945,965 (-)NCBICHM1_1
CRA_TCAGchr7v27158,024,240 - 158,139,944 (-)NCBI
Vipr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912116,041,040 - 116,117,842 (+)NCBIGRCm39mm39
GRCm39 Ensembl12116,041,346 - 116,109,881 (+)Ensembl
GRCm3812116,077,420 - 116,148,637 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12116,077,726 - 116,146,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712117,316,196 - 117,384,734 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612116,519,807 - 116,587,384 (+)NCBImm8
MGSCv3612110,280,083 - 110,347,578 (+)NCBImm8
Cytogenetic Map12F2NCBI
cM Map1262.59NCBI
Vipr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26136,996,664 - 137,070,599 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl6137,001,511 - 137,070,597 (+)Ensembl
Rnor_6.06143,932,960 - 144,009,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06152,871,204 - 152,945,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,347,748 - 143,416,680 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16143,353,934 - 143,422,867 (+)NCBI
Celera6134,667,982 - 134,736,986 (+)NCBICelera
Cytogenetic Map6q33NCBI
Vipr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555791,160,620 - 1,209,848 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555791,160,620 - 1,212,711 (-)NCBIChiLan1.0ChiLan1.0
VIPR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17162,306,477 - 162,425,860 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7162,306,477 - 162,422,788 (-)Ensemblpanpan1.1panPan2
VIPR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11620,925,032 - 20,987,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1620,927,991 - 20,987,785 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1621,432,331 - 21,491,528 (-)NCBI
ROS_Cfam_1.01622,660,335 - 22,719,946 (-)NCBI
UMICH_Zoey_3.11621,028,013 - 21,087,077 (-)NCBI
UNSW_CanFamBas_1.01621,611,058 - 21,670,421 (-)NCBI
UU_Cfam_GSD_1.01621,665,914 - 21,725,151 (-)NCBI
Vipr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118328,956 - 410,359 (+)NCBI
SpeTri2.0NW_004936856859,009 - 866,239 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VIPR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121126,917,862 - 127,022,834 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl21126,917,880 - 127,022,758 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607223,466,663 - 23,573,079 (-)NCBIVero_WHO_p1.0
Vipr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624800125,732 - 188,200 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High
Medium
Low 3 1 1 3
Below cutoff 6 3 3 1 2 15 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017860   ⟹   ENSSSCP00000017379
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18396,379 - 466,408 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000037201   ⟹   ENSSSCP00000048966
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18396,263 - 518,102 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000045341   ⟹   ENSSSCP00000049056
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18396,263 - 467,389 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000059584   ⟹   ENSSSCP00000041535
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18396,263 - 467,389 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000069408   ⟹   ENSSSCP00000063557
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18398,379 - 452,860 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000082296   ⟹   ENSSSCP00000071550
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl18398,379 - 467,389 (+)Ensembl
RefSeq Acc Id: NM_001195117   ⟹   NP_001182046
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.118396,379 - 466,408 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001182046 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADL56950 (Get FASTA)   NCBI Sequence Viewer  
  AIB08848 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001182046   ⟸   NM_001195117
- Peptide Label: precursor
- UniProtKB: E0Y442 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000041535   ⟸   ENSSSCT00000059584
RefSeq Acc Id: ENSSSCP00000049056   ⟸   ENSSSCT00000045341
RefSeq Acc Id: ENSSSCP00000063557   ⟸   ENSSSCT00000069408
RefSeq Acc Id: ENSSSCP00000017379   ⟸   ENSSSCT00000017860
RefSeq Acc Id: ENSSSCP00000048966   ⟸   ENSSSCT00000037201
RefSeq Acc Id: ENSSSCP00000071550   ⟸   ENSSSCT00000082296

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016403 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017379 UniProtKB/TrEMBL
  ENSSSCP00000041535 UniProtKB/TrEMBL
  ENSSSCP00000048966 UniProtKB/TrEMBL
  ENSSSCP00000049056 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000063557 UniProtKB/TrEMBL
  ENSSSCP00000071550 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017860 UniProtKB/TrEMBL
  ENSSSCT00000037201 UniProtKB/TrEMBL
  ENSSSCT00000045341 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000059584 UniProtKB/TrEMBL
  ENSSSCT00000069408 UniProtKB/TrEMBL
  ENSSSCT00000082296 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1240.10 UniProtKB/TrEMBL
InterPro GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPCR_2_VIP_rcpt UniProtKB/TrEMBL
  GPCR_2_VIP_rcpt_2 UniProtKB/TrEMBL
KEGG Report ssc:100499553 UniProtKB/TrEMBL
NCBI Gene VIPR2 ENTREZGENE
PANTHER PTHR45620:SF22 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
PRINTS GPCRSECRETIN UniProtKB/TrEMBL
  VASOACTVEIPR UniProtKB/TrEMBL
  VIP2RECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
SMART HormR UniProtKB/TrEMBL
Superfamily-SCOP SSF111418 UniProtKB/TrEMBL
UniProt A0A287ACB8_PIG UniProtKB/TrEMBL
  A0A287AYL6_PIG UniProtKB/TrEMBL
  A0A287AYV5_PIG UniProtKB/TrEMBL
  A0A5G2QFP7_PIG UniProtKB/TrEMBL
  A0A5G2R380_PIG UniProtKB/TrEMBL
  E0Y442 ENTREZGENE, UniProtKB/TrEMBL
  F1SHW4_PIG UniProtKB/TrEMBL
UniProt Secondary A0A060D8M0 UniProtKB/TrEMBL
VGNC ID VGNC:94828 ENTREZGENE