COQ8A (coenzyme Q8A) - Rat Genome Database

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Gene: COQ8A (coenzyme Q8A) Sus scrofa
Analyze
Symbol: COQ8A
Name: coenzyme Q8A
RGD ID: 14057338
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN ubiquinone biosynthetic process (inferred); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); cerebellar ataxia (ortholog); coenzyme Q10 deficiency disease (ortholog); FOUND IN membrane (inferred); mitochondrion (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: atypical kinase COQ8A, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1014,596,599 - 14,643,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11014,597,237 - 14,643,394 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21017,096,715 - 17,114,950 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
mitochondrion  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
COQ8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1014,596,599 - 14,643,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11014,597,237 - 14,643,394 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21017,096,715 - 17,114,950 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COQ8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,940,294 - 226,987,544 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1226,940,286 - 226,987,544 (+)EnsemblGRCh38hg38GRCh38
GRCh371227,127,995 - 227,175,245 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,194,561 - 225,241,869 (+)NCBINCBI36Build 36hg18NCBI36
Build 341223,434,723 - 223,481,979NCBI
Celera1200,318,754 - 200,366,064 (+)NCBICelera
Cytogenetic Map1q42.13NCBI
HuRef1197,644,481 - 197,691,835 (+)NCBIHuRef
CHM1_11228,400,721 - 228,447,734 (+)NCBICHM1_1
T2T-CHM13v2.01226,128,212 - 226,175,909 (+)NCBIT2T-CHM13v2.0
Coq8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,992,803 - 180,023,585 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1179,992,803 - 180,027,167 (-)EnsemblGRCm39 Ensembl
GRCm381180,165,238 - 180,196,020 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,165,238 - 180,199,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv371182,095,369 - 182,126,151 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361182,001,815 - 182,032,687 (-)NCBIMGSCv36mm8
Celera1187,227,199 - 187,260,762 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map184.15NCBI
Coq8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81394,436,680 - 94,465,535 (-)NCBIGRCr8
mRatBN7.21391,904,731 - 91,933,588 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1391,904,739 - 91,931,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1394,409,919 - 94,436,615 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01395,810,087 - 95,836,779 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01392,984,796 - 93,011,486 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01398,451,629 - 98,480,438 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1398,451,637 - 98,480,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013103,459,488 - 103,488,382 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41395,869,376 - 95,896,742 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11396,058,311 - 96,085,678 (-)NCBI
Celera1391,452,681 - 91,479,411 (-)NCBICelera
Cytogenetic Map13q26NCBI
Coq8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540610,180,415 - 10,217,505 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540610,180,415 - 10,217,450 (-)NCBIChiLan1.0ChiLan1.0
COQ8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2122,552,550 - 22,600,426 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1122,500,916 - 22,548,235 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01202,398,986 - 202,446,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11207,390,883 - 207,436,008 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1207,390,883 - 207,436,008 (+)Ensemblpanpan1.1panPan2
COQ8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1738,085,441 - 38,123,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl738,085,885 - 38,122,974 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha737,568,104 - 37,605,640 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0737,920,065 - 37,957,603 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl737,919,586 - 37,957,561 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1737,759,043 - 37,796,576 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0737,766,177 - 37,803,725 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0738,036,583 - 38,074,123 (-)NCBIUU_Cfam_GSD_1.0
Coq8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934451,063,067 - 51,098,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365263,648,386 - 3,684,238 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365263,648,447 - 3,684,230 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COQ8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1252,780,593 - 2,827,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl252,779,504 - 2,826,538 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660552,745,315 - 2,814,504 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coq8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477112,274,812 - 12,316,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477112,274,812 - 12,315,007 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COQ8A
1607 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 2 1 2 1 2
Low 9 2 3 4 22 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011883   ⟹   ENSSSCP00000011579
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,596,599 - 14,641,379 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000050670   ⟹   ENSSSCP00000049243
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,772 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000051518   ⟹   ENSSSCP00000054437
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,772 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054103   ⟹   ENSSSCP00000031852
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,772 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054257   ⟹   ENSSSCP00000052336
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,390 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000086305   ⟹   ENSSSCP00000068232
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,772 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000099360   ⟹   ENSSSCP00000078760
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1014,597,303 - 14,643,772 (+)Ensembl
RefSeq Acc Id: XM_021064416   ⟹   XP_020920075
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11014,597,237 - 14,643,394 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064417   ⟹   XP_020920076
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11014,618,925 - 14,643,394 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064418   ⟹   XP_020920077
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11014,597,302 - 14,643,394 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064419   ⟹   XP_020920078
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11014,617,990 - 14,643,394 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020920075   ⟸   XM_021064416
- UniProtKB: A0A8D1RCE0 (UniProtKB/TrEMBL),   A0A286ZK64 (UniProtKB/TrEMBL),   A0A8D0Z8B6 (UniProtKB/TrEMBL),   A0A8D2BV04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920077   ⟸   XM_021064418
- UniProtKB: A0A8D1RCE0 (UniProtKB/TrEMBL),   A0A286ZK64 (UniProtKB/TrEMBL),   A0A8D0Z8B6 (UniProtKB/TrEMBL),   A0A8D2BV04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920078   ⟸   XM_021064419
- UniProtKB: A0A8D1RCE0 (UniProtKB/TrEMBL),   A0A286ZK64 (UniProtKB/TrEMBL),   A0A8D0Z8B6 (UniProtKB/TrEMBL),   A0A8D2BV04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920076   ⟸   XM_021064417
- UniProtKB: A0A8D1RCE0 (UniProtKB/TrEMBL),   A0A286ZK64 (UniProtKB/TrEMBL),   A0A8D0Z8B6 (UniProtKB/TrEMBL),   A0A8D2BV04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000049243   ⟸   ENSSSCT00000050670
RefSeq Acc Id: ENSSSCP00000031852   ⟸   ENSSSCT00000054103
RefSeq Acc Id: ENSSSCP00000052336   ⟸   ENSSSCT00000054257
RefSeq Acc Id: ENSSSCP00000054437   ⟸   ENSSSCT00000051518
RefSeq Acc Id: ENSSSCP00000011579   ⟸   ENSSSCT00000011883
RefSeq Acc Id: ENSSSCP00000068232   ⟸   ENSSSCT00000086305
RefSeq Acc Id: ENSSSCP00000078760   ⟸   ENSSSCT00000099360
Protein Domains
ABC1 atypical kinase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010861 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025029072 UniProtKB/TrEMBL
  ENSSSCG00035022886 UniProtKB/TrEMBL
  ENSSSCG00040024349 UniProtKB/TrEMBL
  ENSSSCG00045024650 UniProtKB/TrEMBL
  ENSSSCG00055019595 UniProtKB/TrEMBL
  ENSSSCG00060076822 UniProtKB/TrEMBL
  ENSSSCG00065016938 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011883.4 UniProtKB/TrEMBL
  ENSSSCT00000050670.3 UniProtKB/TrEMBL
  ENSSSCT00000051518.3 UniProtKB/TrEMBL
  ENSSSCT00000054103 ENTREZGENE
  ENSSSCT00000054103.3 UniProtKB/TrEMBL
  ENSSSCT00000054257.3 UniProtKB/TrEMBL
  ENSSSCT00000086305.2 UniProtKB/TrEMBL
  ENSSSCT00000099360.1 UniProtKB/TrEMBL
  ENSSSCT00025039593.1 UniProtKB/TrEMBL
  ENSSSCT00025039791.1 UniProtKB/TrEMBL
  ENSSSCT00025039911.1 UniProtKB/TrEMBL
  ENSSSCT00025040118.1 UniProtKB/TrEMBL
  ENSSSCT00035029932.1 UniProtKB/TrEMBL
  ENSSSCT00040032721.1 UniProtKB/TrEMBL
  ENSSSCT00045042098.1 UniProtKB/TrEMBL
  ENSSSCT00045042366.1 UniProtKB/TrEMBL
  ENSSSCT00045042527.1 UniProtKB/TrEMBL
  ENSSSCT00045042710.1 UniProtKB/TrEMBL
  ENSSSCT00055038465.1 UniProtKB/TrEMBL
  ENSSSCT00055038672.1 UniProtKB/TrEMBL
  ENSSSCT00055038804.1 UniProtKB/TrEMBL
  ENSSSCT00055038909.1 UniProtKB/TrEMBL
  ENSSSCT00060105635.1 UniProtKB/TrEMBL
  ENSSSCT00065022724.1 UniProtKB/TrEMBL
  ENSSSCT00065022779.1 UniProtKB/TrEMBL
  ENSSSCT00065022788.1 UniProtKB/TrEMBL
InterPro ADCK3_UbiB UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  UbiB_dom UniProtKB/TrEMBL
NCBI Gene COQ8A ENTREZGENE
PANTHER PTHR43851 UniProtKB/TrEMBL
  PTHR43851:SF1 UniProtKB/TrEMBL
Pfam ABC1 UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A286ZK64 ENTREZGENE, UniProtKB/TrEMBL
  A0A287AZ56_PIG UniProtKB/TrEMBL
  A0A287B895_PIG UniProtKB/TrEMBL
  A0A287BEB5_PIG UniProtKB/TrEMBL
  A0A5G2R212_PIG UniProtKB/TrEMBL
  A0A8D0Z8B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IBM0_PIG UniProtKB/TrEMBL
  A0A8D1RBB4_PIG UniProtKB/TrEMBL
  A0A8D1RCE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RFN5_PIG UniProtKB/TrEMBL
  A0A8D2BV04 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FKC9_PIG UniProtKB/TrEMBL
  F1S8Q4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95818 ENTREZGENE