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Gene: GCLM (glutamate-cysteine ligase modifier subunit) Sus scrofa
Symbol: GCLM
Name: glutamate-cysteine ligase modifier subunit
Description: ENCODES a protein that exhibits glutamate-cysteine ligase activity (inferred); glutamate-cysteine ligase catalytic subunit binding (inferred); INVOLVED IN apoptotic mitochondrial changes (inferred); cellular response to leukemia inhibitory factor (inferred); cysteine metabolic process (inferred); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; cysteine metabolic pathway; glutamic acid/glutamate metabolic pathway; ASSOCIATED WITH berylliosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Liver Injury (ortholog); INTERACTS WITH zearalenone
Type: protein-coding
RefSeq Status: MODEL
Also known as: glutamate--cysteine ligase regulatory subunit
Homo sapiens (human) : GCLM (glutamate-cysteine ligase modifier subunit)  HGNC  Alliance
Mus musculus (house mouse) : Gclm (glutamate-cysteine ligase, modifier subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gclm (glutamate cysteine ligase, modifier subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gclm (glutamate-cysteine ligase modifier subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : GCLM (glutamate-cysteine ligase modifier subunit)
Canis lupus familiaris (dog) : GCLM (glutamate-cysteine ligase modifier subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gclm (glutamate-cysteine ligase modifier subunit)
Chlorocebus sabaeus (African green monkey) : GCLM (glutamate-cysteine ligase modifier subunit)
Heterocephalus glaber (naked mole-rat) : Gclm (glutamate-cysteine ligase modifier subunit)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl4123,371,193 - 123,390,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14123,371,198 - 123,390,130 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24135,017,027 - 135,035,890 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on GCLM
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14055570
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.