EXOC6B (exocyst complex component 6B) - Rat Genome Database

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Gene: EXOC6B (exocyst complex component 6B) Sus scrofa
Analyze
Symbol: EXOC6B
Name: exocyst complex component 6B
RGD ID: 14052537
Description: INVOLVED IN exocytosis (inferred); Golgi to plasma membrane transport (inferred); intracellular protein transport (inferred); ASSOCIATED WITH congenital disorder of glycosylation type IIb (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN exocyst (inferred); membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,939,173 - 70,546,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,939,156 - 70,546,702 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2373,603,742 - 73,721,806 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
exocyst  (IBA,IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EXOC6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,939,173 - 70,546,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,939,156 - 70,546,702 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2373,603,742 - 73,721,806 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXOC6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38272,175,984 - 72,826,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl272,175,984 - 72,826,041 (-)EnsemblGRCh38hg38GRCh38
GRCh37272,403,113 - 73,053,162 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36272,259,952 - 72,906,685 (-)NCBINCBI36Build 36hg18NCBI36
Celera272,256,455 - 72,902,975 (-)NCBICelera
Cytogenetic Map2p13.2NCBI
HuRef272,142,207 - 72,788,725 (-)NCBIHuRef
CHM1_1272,335,870 - 72,983,318 (-)NCBICHM1_1
T2T-CHM13v2.0272,189,067 - 72,838,971 (-)NCBIT2T-CHM13v2.0
Exoc6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39684,595,468 - 85,046,524 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl684,595,469 - 85,046,495 (-)EnsemblGRCm39 Ensembl
GRCm38684,618,486 - 85,070,258 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl684,618,487 - 85,069,513 (-)EnsemblGRCm38mm10GRCm38
MGSCv37684,568,480 - 85,019,507 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36684,584,144 - 85,035,171 (-)NCBIMGSCv36mm8
Celera686,599,576 - 87,040,678 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map636.55NCBI
Exoc6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84118,652,279 - 119,107,725 (-)NCBIGRCr8
mRatBN7.24117,094,741 - 117,550,221 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4117,094,741 - 117,550,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4122,575,910 - 123,031,498 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04118,351,070 - 118,806,629 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04116,964,002 - 117,419,400 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04116,314,695 - 116,786,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4116,314,695 - 116,786,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04180,900,780 - 181,368,585 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44118,788,652 - 119,239,982 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4106,081,225 - 106,534,156 (-)NCBICelera
Cytogenetic Map4q34NCBI
Exoc6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,777,595 - 13,305,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,777,638 - 13,308,358 (+)NCBIChiLan1.0ChiLan1.0
EXOC6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21253,555,060 - 54,208,057 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A53,557,824 - 54,210,805 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A72,225,310 - 72,878,506 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A73,720,046 - 74,371,952 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A73,723,392 - 74,371,820 (-)Ensemblpanpan1.1panPan2
EXOC6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,986,330 - 50,607,658 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,986,390 - 50,604,451 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1749,634,486 - 50,255,180 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,854,729 - 51,476,341 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1750,854,749 - 51,476,337 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11749,870,948 - 50,485,269 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,936,727 - 50,551,212 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01750,496,728 - 51,125,294 (+)NCBIUU_Cfam_GSD_1.0
Exoc6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,937,872 - 12,515,233 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649116,055,503 - 16,633,428 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649116,056,059 - 16,633,405 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11434,280,579 - 35,011,207 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1434,344,898 - 34,891,495 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604577,055,291 - 77,735,017 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624762791,042 - 1,424,807 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624762790,892 - 1,435,485 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EXOC6B
13660 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 2 23 2 3 3
Low 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000032116   ⟹   ENSSSCP00000026840
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl369,939,173 - 70,546,700 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000057848   ⟹   ENSSSCP00000031282
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl369,939,179 - 70,546,699 (+)Ensembl
RefSeq Acc Id: XM_013996035   ⟹   XP_013851489
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1369,939,156 - 70,546,702 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013851489   ⟸   XM_013996035
- UniProtKB: A0A286ZIH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000026840   ⟸   ENSSSCT00000032116
RefSeq Acc Id: ENSSSCP00000031282   ⟸   ENSSSCT00000057848
Protein Domains
Exocyst complex component EXOC6/Sec15 N-terminal   Exocyst complex subunit EXOC6/Sec15 C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005028596 UniProtKB/TrEMBL
  ENSSSCG00015022779 UniProtKB/TrEMBL
  ENSSSCG00025060757 UniProtKB/TrEMBL
  ENSSSCG00030038645 UniProtKB/TrEMBL
  ENSSSCG00060015857 UniProtKB/TrEMBL
  ENSSSCG00070029460 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032116.4 UniProtKB/TrEMBL
  ENSSSCT00000057848 ENTREZGENE
  ENSSSCT00000057848.3 UniProtKB/TrEMBL
  ENSSSCT00005045579.1 UniProtKB/TrEMBL
  ENSSSCT00005045634.1 UniProtKB/TrEMBL
  ENSSSCT00005045795.1 UniProtKB/TrEMBL
  ENSSSCT00005045840.1 UniProtKB/TrEMBL
  ENSSSCT00005045869.1 UniProtKB/TrEMBL
  ENSSSCT00005045901.1 UniProtKB/TrEMBL
  ENSSSCT00015030214.1 UniProtKB/TrEMBL
  ENSSSCT00015030236.1 UniProtKB/TrEMBL
  ENSSSCT00015030343.1 UniProtKB/TrEMBL
  ENSSSCT00015030525.1 UniProtKB/TrEMBL
  ENSSSCT00015030867.1 UniProtKB/TrEMBL
  ENSSSCT00015030995.1 UniProtKB/TrEMBL
  ENSSSCT00025083186.1 UniProtKB/TrEMBL
  ENSSSCT00025083579.1 UniProtKB/TrEMBL
  ENSSSCT00025084379.1 UniProtKB/TrEMBL
  ENSSSCT00030053802.1 UniProtKB/TrEMBL
  ENSSSCT00030053826.1 UniProtKB/TrEMBL
  ENSSSCT00030053852.1 UniProtKB/TrEMBL
  ENSSSCT00030053930.1 UniProtKB/TrEMBL
  ENSSSCT00030053988.1 UniProtKB/TrEMBL
  ENSSSCT00030054005.1 UniProtKB/TrEMBL
  ENSSSCT00030054061.1 UniProtKB/TrEMBL
  ENSSSCT00060021159.1 UniProtKB/TrEMBL
  ENSSSCT00070059213.1 UniProtKB/TrEMBL
  ENSSSCT00070059219.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.30 UniProtKB/TrEMBL
  1.20.58.670 UniProtKB/TrEMBL
InterPro EXOC6/Sec15 UniProtKB/TrEMBL
  EXOC6/Sec15_C_dom1 UniProtKB/TrEMBL
  EXOC6_Sec15_N UniProtKB/TrEMBL
  EXOC6PINT-1/Sec15/Tip20_C_dom2 UniProtKB/TrEMBL
  Sec15_C UniProtKB/TrEMBL
NCBI Gene EXOC6B ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 6B UniProtKB/TrEMBL
  PTHR12702 UniProtKB/TrEMBL
Pfam EXOC6_Sec15_N UniProtKB/TrEMBL
  Sec15 UniProtKB/TrEMBL
PIRSF Sec15 UniProtKB/TrEMBL
UniProt A0A286ZIH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A480UT78_PIG UniProtKB/TrEMBL
  A0A4X1W2F0_PIG UniProtKB/TrEMBL
  A0A8D0JJ86_PIG UniProtKB/TrEMBL
  A0A8D0JKQ2_PIG UniProtKB/TrEMBL
  A0A8D0JKR9_PIG UniProtKB/TrEMBL
  A0A8D0JMZ1_PIG UniProtKB/TrEMBL
  A0A8D0JSZ9_PIG UniProtKB/TrEMBL
  A0A8D0N5L6_PIG UniProtKB/TrEMBL
  A0A8D0WQ68_PIG UniProtKB/TrEMBL
  A0A8D0WQA3_PIG UniProtKB/TrEMBL
  A0A8D0WU08_PIG UniProtKB/TrEMBL
  A0A8D0WU86_PIG UniProtKB/TrEMBL
  A0A8D1C7Z9_PIG UniProtKB/TrEMBL
  I3LRV0_PIG UniProtKB/TrEMBL
UniProt Secondary A0A4X1W7F7 UniProtKB/TrEMBL
VGNC ID VGNC:106578 ENTREZGENE