SLC5A3 (solute carrier family 5 member 3) - Rat Genome Database

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Gene: SLC5A3 (solute carrier family 5 member 3) Sus scrofa
Analyze
Symbol: SLC5A3
Name: solute carrier family 5 member 3
RGD ID: 14051146
Description: ENCODES a protein that exhibits fucose transmembrane transporter activity (ortholog); pentose transmembrane transporter activity (ortholog); polyol transmembrane transporter activity (ortholog); INVOLVED IN fucose transmembrane transport (ortholog); inositol metabolic process (ortholog); myo-inositol transport (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); bipolar disorder (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/myo-inositol cotransporter; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13197,711,679 - 197,718,695 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113197,688,632 - 197,723,323 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC5A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13197,711,679 - 197,718,695 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113197,688,632 - 197,723,323 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC5A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382134,073,578 - 34,106,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2134,073,578 - 34,106,260 (+)EnsemblGRCh38hg38GRCh38
GRCh372135,445,878 - 35,478,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,367,740 - 34,400,431 (+)NCBINCBI36Build 36hg18NCBI36
Build 342134,389,367 - 34,391,524NCBI
Celera2120,645,433 - 20,678,122 (+)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2120,945,609 - 20,957,018 (+)NCBIHuRef
CHM1_12135,008,142 - 35,040,833 (+)NCBICHM1_1
T2T-CHM13v2.02132,455,648 - 32,488,333 (+)NCBIT2T-CHM13v2.0
Slc5a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,855,210 - 91,884,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,855,210 - 91,884,361 (+)EnsemblGRCm39 Ensembl
GRCm381692,058,322 - 92,087,473 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1692,058,322 - 92,087,473 (+)EnsemblGRCm38mm10GRCm38
MGSCv371692,058,567 - 92,087,718 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361691,965,916 - 91,968,072 (+)NCBIMGSCv36mm8
Celera1693,161,374 - 93,172,132 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1653.44NCBI
Slc5a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,799,787 - 44,802,233 (+)NCBIGRCr8
mRatBN7.21131,313,847 - 31,316,293 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1131,295,476 - 31,318,883 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1140,008,115 - 40,010,560 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,679,563 - 32,682,008 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,843,057 - 31,845,503 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01132,229,366 - 32,231,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01135,834,279 - 35,836,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41132,063,275 - 32,065,721 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11132,119,576 - 32,121,733 (+)NCBI
Celera1130,970,690 - 30,973,136 (+)NCBICelera
Cytogenetic Map11q11NCBI
Slc5a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540733,494,816 - 33,511,968 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540733,460,238 - 33,511,889 (+)NCBIChiLan1.0ChiLan1.0
MRPS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22230,191,861 - 30,261,300 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12125,050,026 - 25,119,478 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02120,441,365 - 20,510,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12133,809,456 - 33,879,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2133,862,033 - 33,879,670 (+)Ensemblpanpan1.1panPan2
SLC5A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13128,610,332 - 28,635,233 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3128,610,332 - 28,635,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3128,607,798 - 28,632,691 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03128,815,044 - 28,839,960 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3128,815,024 - 28,840,301 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13128,681,748 - 28,706,621 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03128,696,566 - 28,721,418 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03129,195,487 - 29,220,373 (+)NCBIUU_Cfam_GSD_1.0
Slc5a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497129,152,449 - 29,183,192 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365008,284,631 - 8,296,387 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC5A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,104,938 - 58,131,225 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666071601,202 - 634,141 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc5a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474522,231,887 - 22,258,965 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474522,231,434 - 22,264,555 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC5A3
738 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 7 3 3 5 16 3 1
Low 3 1 2 7 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000065757   ⟹   ENSSSCP00000039535
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13197,711,679 - 197,718,695 (+)Ensembl
RefSeq Acc Id: XM_005657149   ⟹   XP_005657206
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113197,688,632 - 197,723,323 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005657206   ⟸   XM_005657149
- UniProtKB: A0A287A6C9 (UniProtKB/TrEMBL),   A0A8D0MUJ3 (UniProtKB/TrEMBL),   A0A0B8RT63 (UniProtKB/TrEMBL),   D3K5N9 (UniProtKB/TrEMBL),   A0A8D1DZU2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000039535   ⟸   ENSSSCT00000065757


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034167 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005020002 UniProtKB/TrEMBL
  ENSSSCG00015017729 UniProtKB/TrEMBL
  ENSSSCG00025010549 UniProtKB/TrEMBL
  ENSSSCG00030003949 UniProtKB/TrEMBL
  ENSSSCG00035031433 UniProtKB/TrEMBL
  ENSSSCG00040025610 UniProtKB/TrEMBL
  ENSSSCG00045023403 UniProtKB/TrEMBL
  ENSSSCG00050018582 UniProtKB/TrEMBL
  ENSSSCG00055024188 UniProtKB/TrEMBL
  ENSSSCG00060074510 UniProtKB/TrEMBL
  ENSSSCG00065030732 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000065757 ENTREZGENE
  ENSSSCT00000065757.3 UniProtKB/TrEMBL
  ENSSSCT00005031474.1 UniProtKB/TrEMBL
  ENSSSCT00015023368.1 UniProtKB/TrEMBL
  ENSSSCT00025013861.1 UniProtKB/TrEMBL
  ENSSSCT00030005147.1 UniProtKB/TrEMBL
  ENSSSCT00035041602.1 UniProtKB/TrEMBL
  ENSSSCT00040034127.1 UniProtKB/TrEMBL
  ENSSSCT00045039974.1 UniProtKB/TrEMBL
  ENSSSCT00050025157.1 UniProtKB/TrEMBL
  ENSSSCT00055047618.1 UniProtKB/TrEMBL
  ENSSSCT00060101886.1 UniProtKB/TrEMBL
  ENSSSCT00065041527.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1730.10 UniProtKB/TrEMBL
InterPro Na/Glc_symporter_sf UniProtKB/TrEMBL
  Na/solute_symporter UniProtKB/TrEMBL
  Na/solute_symporter_CS UniProtKB/TrEMBL
  SMIT UniProtKB/TrEMBL
KEGG Report ssc:110255177 UniProtKB/TrEMBL
NCBI Gene SLC5A3 ENTREZGENE
PANTHER SODIUM/MYO-INOSITOL COTRANSPORTER UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 5 UniProtKB/TrEMBL
Pfam SSF UniProtKB/TrEMBL
PROSITE NA_SOLUT_SYMP_1 UniProtKB/TrEMBL
  NA_SOLUT_SYMP_2 UniProtKB/TrEMBL
  NA_SOLUT_SYMP_3 UniProtKB/TrEMBL
UniProt A0A0B8RT63 ENTREZGENE
  A0A287A6C9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MUJ3 ENTREZGENE
  A0A8D1DZU2 ENTREZGENE, UniProtKB/TrEMBL
  D3K5N9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8D0MUJ3 UniProtKB/TrEMBL
VGNC ID VGNC:93144 ENTREZGENE