MFF (mitochondrial fission factor) - Rat Genome Database

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Gene: MFF (mitochondrial fission factor) Sus scrofa
Analyze
Symbol: MFF
Name: mitochondrial fission factor
RGD ID: 14050758
Description: ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); mitochondrial fission (ortholog); mitochondrion morphogenesis (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH Encephalopathy due to Defective Mitochondrial and Peroxisomal Fission 2 (ortholog); mitochondrial encephalomyopathy (ortholog); myocardial infarction (ortholog); FOUND IN mitochondrial membrane (ortholog); synaptic vesicle (ortholog); synaptic vesicle membrane (ortholog); INTERACTS WITH cadmium atom; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15128,768,348 - 128,799,345 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115128,768,441 - 128,799,355 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215142,603,384 - 142,605,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
MFF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15128,768,348 - 128,799,345 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115128,768,441 - 128,799,355 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215142,603,384 - 142,605,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2227,325,151 - 227,357,836 (+)EnsemblGRCh38hg38GRCh38
GRCh382227,325,233 - 227,357,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372228,189,967 - 228,222,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,900,472 - 227,930,793 (+)NCBINCBI36hg18NCBI36
Build 342228,017,732 - 228,048,052NCBI
Celera2221,961,362 - 221,991,712 (+)NCBI
Cytogenetic Map2q36.3NCBI
HuRef2220,033,273 - 220,065,950 (+)NCBIHuRef
CHM1_12228,195,676 - 228,228,351 (+)NCBICHM1_1
Mff
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39182,702,599 - 82,730,111 (+)NCBIGRCm39mm39
GRCm39 Ensembl182,702,611 - 82,730,115 (+)Ensembl
GRCm38182,724,890 - 82,752,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl182,724,890 - 82,752,394 (+)EnsemblGRCm38mm10GRCm38
MGSCv37182,721,493 - 82,748,965 (+)NCBIGRCm37mm9NCBIm37
MGSCv36182,603,942 - 82,631,414 (+)NCBImm8
Celera182,791,317 - 82,818,740 (+)NCBICelera
Cytogenetic Map1C5NCBI
Mff
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2984,007,798 - 84,036,039 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl984,007,798 - 84,036,039 (+)Ensembl
Rnor_6.0988,490,280 - 88,518,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl988,493,593 - 88,517,827 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl990,880,614 - 90,908,852 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0988,237,923 - 88,266,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,045,236 - 82,071,135 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1982,226,339 - 82,254,116 (+)NCBI
Celera981,449,284 - 81,477,522 (+)NCBICelera
Cytogenetic Map9q34NCBI
Mff
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554537,221,244 - 7,256,029 (-)NCBIChiLan1.0ChiLan1.0
MFF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B233,381,466 - 233,413,784 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B233,381,466 - 233,413,778 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B114,569,893 - 114,602,158 (+)NCBIMhudiblu_PPA_v0panPan3
MFF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12540,111,860 - 40,142,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2540,111,894 - 40,141,776 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2540,729,454 - 40,759,752 (+)NCBI
ROS_Cfam_1.02540,359,046 - 40,389,383 (+)NCBI
UMICH_Zoey_3.12540,296,257 - 40,326,536 (+)NCBI
UNSW_CanFamBas_1.02540,136,663 - 40,166,970 (+)NCBI
UU_Cfam_GSD_1.02540,310,286 - 40,340,831 (+)NCBI
Mff
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303182,303,437 - 182,336,660 (+)NCBI
SpeTri2.0NW_0049365258,604,478 - 8,636,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110113,348,330 - 113,381,875 (+)NCBI
ChlSab1.1 Ensembl10113,348,446 - 113,381,162 (+)Ensembl
Vero_WHO_p1.0NW_02366604086,070,374 - 86,102,885 (-)NCBI
Mff
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248431,626,800 - 1,664,906 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000058879   ⟹   ENSSSCP00000056618
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,768,352 - 128,799,345 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000071461   ⟹   ENSSSCP00000067790
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,768,371 - 128,799,170 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000083320   ⟹   ENSSSCP00000064376
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,768,412 - 128,799,341 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000089611   ⟹   ENSSSCP00000067718
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,768,371 - 128,799,172 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000089942   ⟹   ENSSSCP00000074464
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,768,348 - 128,799,340 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000090071   ⟹   ENSSSCP00000061438
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15128,773,183 - 128,799,341 (+)Ensembl
RefSeq Acc Id: NM_001244126   ⟹   NP_001231055
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115128,768,441 - 128,799,355 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001231055 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001231055   ⟸   NM_001244126
- Sequence:
RefSeq Acc Id: ENSSSCP00000064376   ⟸   ENSSSCT00000083320
RefSeq Acc Id: ENSSSCP00000056618   ⟸   ENSSSCT00000058879
RefSeq Acc Id: ENSSSCP00000061438   ⟸   ENSSSCT00000090071
RefSeq Acc Id: ENSSSCP00000067718   ⟸   ENSSSCT00000089611
RefSeq Acc Id: ENSSSCP00000074464   ⟸   ENSSSCT00000089942
RefSeq Acc Id: ENSSSCP00000067790   ⟸   ENSSSCT00000071461
Protein Domains
Miff


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031572 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070013845 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000056618 UniProtKB/TrEMBL
  ENSSSCP00000061438 UniProtKB/TrEMBL
  ENSSSCP00000064376 UniProtKB/TrEMBL
  ENSSSCP00000067718 UniProtKB/TrEMBL
  ENSSSCP00000067790 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000074464 UniProtKB/TrEMBL
  ENSSSCP00070022504 UniProtKB/TrEMBL
  ENSSSCP00070022527 UniProtKB/TrEMBL
  ENSSSCP00070022566 UniProtKB/TrEMBL
  ENSSSCP00070022570 UniProtKB/TrEMBL
  ENSSSCP00070022575 UniProtKB/TrEMBL
  ENSSSCP00070022577 UniProtKB/TrEMBL
  ENSSSCP00070022581 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000058879 UniProtKB/TrEMBL
  ENSSSCT00000071461 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000083320 UniProtKB/TrEMBL
  ENSSSCT00000089611 UniProtKB/TrEMBL
  ENSSSCT00000089942 UniProtKB/TrEMBL
  ENSSSCT00000090071 UniProtKB/TrEMBL
  ENSSSCT00070027063 UniProtKB/TrEMBL
  ENSSSCT00070027086 UniProtKB/TrEMBL
  ENSSSCT00070027126 UniProtKB/TrEMBL
  ENSSSCT00070027132 UniProtKB/TrEMBL
  ENSSSCT00070027138 UniProtKB/TrEMBL
  ENSSSCT00070027140 UniProtKB/TrEMBL
  ENSSSCT00070027147 UniProtKB/TrEMBL
InterPro Mff-like_dom UniProtKB/TrEMBL
  Mff/Tango-11 UniProtKB/TrEMBL
NCBI Gene MFF ENTREZGENE
PANTHER PTHR16501 UniProtKB/TrEMBL
Pfam Miff UniProtKB/TrEMBL
UniProt A0A287BJB9_PIG UniProtKB/TrEMBL
  A0A4X1TYG7_PIG UniProtKB/TrEMBL
  A0A4X1TYM7_PIG UniProtKB/TrEMBL
  A0A4X1TYP3_PIG UniProtKB/TrEMBL
  A0A4X1U187_PIG UniProtKB/TrEMBL
  A0A4X1U3M8_PIG UniProtKB/TrEMBL
  A0A4X1U473_PIG UniProtKB/TrEMBL
  A0A4X1U478_PIG UniProtKB/TrEMBL
  A0A5G2QHE9_PIG UniProtKB/TrEMBL
  A0A5G2QIV2_PIG UniProtKB/TrEMBL
  A0A5G2QS84_PIG UniProtKB/TrEMBL
  A0A5G2RAT6_PIG UniProtKB/TrEMBL
  A0A5G2RH58_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103985 ENTREZGENE