TKTL1 (transketolase like 1) - Rat Genome Database

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Gene: TKTL1 (transketolase like 1) Sus scrofa
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Symbol: TKTL1
Name: transketolase like 1
RGD ID: 14042144
Description: ENCODES a protein that exhibits catalytic activity (inferred); metal ion binding (inferred); transferase activity (inferred); ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transketolase-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,839,995 - 124,867,614 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,840,072 - 124,867,313 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
TKTL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,839,995 - 124,867,614 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,840,072 - 124,867,313 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TKTL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,295,795 - 154,330,350 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX154,295,795 - 154,330,350 (+)EnsemblGRCh38hg38GRCh38
GRCh37X153,524,148 - 153,558,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,177,345 - 153,211,894 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,044,997 - 153,079,545NCBI
CeleraX153,685,095 - 153,719,771 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,101,239 - 142,134,950 (+)NCBIHuRef
CHM1_1X153,435,658 - 153,470,347 (+)NCBICHM1_1
T2T-CHM13v2.0X152,532,310 - 152,566,865 (+)NCBIT2T-CHM13v2.0
Tktl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,220,865 - 73,252,104 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,220,865 - 73,252,106 (+)EnsemblGRCm39 Ensembl
GRCm38X74,177,259 - 74,208,498 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,177,259 - 74,208,500 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,422,598 - 71,453,837 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,430,004 - 70,461,211 (+)NCBIMGSCv36mm8
CeleraX65,429,659 - 65,462,614 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
Tktl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X151,954,261 - 151,987,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,954,175 - 151,987,208 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,095,403 - 154,128,342 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X157,658,639 - 157,691,577 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X155,330,437 - 155,363,375 (+)NCBIRnor_WKY
Rnor_6.0X156,507,797 - 156,540,733 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,507,797 - 156,540,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,248,857 - 152,281,793 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01151,506,633 - 151,523,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,144,916 - 160,177,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1135,909,517 - 135,940,852 (-)NCBICelera
Cytogenetic MapXq37NCBI
Tktl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580829,594 - 851,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955580829,653 - 851,422 (+)NCBIChiLan1.0ChiLan1.0
TKTL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v0X143,736,589 - 143,772,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TKTL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,007,270 - 122,034,500 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,007,282 - 122,034,255 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX107,336,003 - 107,363,191 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X125,148,940 - 125,176,143 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,148,958 - 125,176,646 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X120,918,050 - 120,945,228 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,433,366 - 123,460,383 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,194,859 - 123,221,957 (+)NCBIUU_Cfam_GSD_1.0
Tktl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,310,855 - 119,346,858 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049368091,048,672 - 1,084,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TKTL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,607,766 - 128,642,074 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,607,901 - 128,642,063 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606566,535,359 - 66,559,996 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tktl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946760,078 - 775,073 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system reproductive system
High
Medium
Low 2
Below cutoff 11 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000031565   ⟹   ENSSSCP00000020565
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,839,995 - 124,867,614 (+)Ensembl
RefSeq Acc Id: XM_021080741   ⟹   XP_020936400
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,840,465 - 124,867,313 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021080743   ⟹   XP_020936402
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,840,072 - 124,867,313 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020936400 (Get FASTA)   NCBI Sequence Viewer  
  XP_020936402 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020936402   ⟸   XM_021080743
- UniProtKB: A0A4X1TES9 (UniProtKB/TrEMBL),   I3L954 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020936400   ⟸   XM_021080741
- UniProtKB: A0A4X1TES9 (UniProtKB/TrEMBL),   I3L954 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000020565   ⟸   ENSSSCT00000031565
Protein Domains
Transket_pyr


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029443 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025044658 UniProtKB/TrEMBL
  ENSSSCG00030026907 UniProtKB/TrEMBL
  ENSSSCG00045031796 UniProtKB/TrEMBL
  ENSSSCG00055007366 UniProtKB/TrEMBL
  ENSSSCG00070009254 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000020565 ENTREZGENE
  ENSSSCP00000020565.2 UniProtKB/TrEMBL
  ENSSSCP00025025732.1 UniProtKB/TrEMBL
  ENSSSCP00030017226.1 UniProtKB/TrEMBL
  ENSSSCP00045037797.1 UniProtKB/TrEMBL
  ENSSSCP00055011257.1 UniProtKB/TrEMBL
  ENSSSCP00070014928.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031565 ENTREZGENE
  ENSSSCT00000031565.3 UniProtKB/TrEMBL
  ENSSSCT00025060657.1 UniProtKB/TrEMBL
  ENSSSCT00030037605.1 UniProtKB/TrEMBL
  ENSSSCT00045054286.1 UniProtKB/TrEMBL
  ENSSSCT00055014315.1 UniProtKB/TrEMBL
  ENSSSCT00070017985.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.920 UniProtKB/TrEMBL
InterPro THDP-binding UniProtKB/TrEMBL
  Transketo_C/PFOR_II UniProtKB/TrEMBL
  Transketolase-like_Pyr-bd UniProtKB/TrEMBL
  Transketolase_BS UniProtKB/TrEMBL
  Transketolase_C UniProtKB/TrEMBL
  Transketolase_N UniProtKB/TrEMBL
NCBI Gene TKTL1 ENTREZGENE
Pfam Transket_pyr UniProtKB/TrEMBL
  Transketolase_C UniProtKB/TrEMBL
  Transketolase_N UniProtKB/TrEMBL
PROSITE TRANSKETOLASE_2 UniProtKB/TrEMBL
SMART Transket_pyr UniProtKB/TrEMBL
Superfamily-SCOP SSF52518 UniProtKB/TrEMBL
  SSF52922 UniProtKB/TrEMBL
UniProt A0A4X1TES9 ENTREZGENE, UniProtKB/TrEMBL
  I3L954 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94009 ENTREZGENE