ZP3 (zona pellucida glycoprotein 3) - Rat Genome Database

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Gene: ZP3 (zona pellucida glycoprotein 3) Sus scrofa
Analyze
Symbol: ZP3
Name: zona pellucida glycoprotein 3
RGD ID: 14041751
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN positive regulation of type IV hypersensitivity; binding of sperm to zona pellucida (ortholog); blastocyst formation (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 3 (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); egg coat (ortholog); extracellular space (ortholog); INTERACTS WITH N-acetyl-L-cysteine; zearalenone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: sperm receptor; zona pellucida glycoprotein 3-beta; zona pellucida glycoprotein ZP3-beta; zona pellucida protein 3-beta; zona pellucida protein C; zona pellucida sperm-binding protein 3; Zp-3; zp-3-beta; zp3-beta; ZPC
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl39,934,761 - 9,944,941 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.139,934,760 - 9,944,924 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.239,837,980 - 9,848,145 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3pter-p15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1418987   PMID:7841460   PMID:8562067   PMID:8697800   PMID:12878193   PMID:14681463   PMID:15579591   PMID:15788399   PMID:17145712   PMID:17550356   PMID:21295838  


Genomics

Comparative Map Data
ZP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl39,934,761 - 9,944,941 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.139,934,760 - 9,944,924 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.239,837,980 - 9,848,145 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3pter-p15NCBI
ZP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl776,397,518 - 76,442,071 (+)EnsemblGRCh38hg38GRCh38
GRCh38776,397,522 - 76,442,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37776,026,839 - 76,071,386 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,864,804 - 75,909,324 (+)NCBINCBI36hg18NCBI36
Build 34775,671,518 - 75,716,038NCBI
Celera770,895,359 - 70,931,910 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef771,113,333 - 71,158,989 (+)NCBIHuRef
CHM1_1775,957,109 - 76,001,648 (+)NCBICHM1_1
CRA_TCAGchr7v2775,359,905 - 75,404,452 (+)NCBI
Zp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,008,959 - 136,017,478 (+)NCBIGRCm39mm39
GRCm39 Ensembl5136,008,953 - 136,017,478 (+)Ensembl
GRCm385135,980,105 - 135,988,624 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,980,099 - 135,988,624 (+)EnsemblGRCm38mm10GRCm38
MGSCv375136,455,975 - 136,464,494 (+)NCBIGRCm37mm9NCBIm37
MGSCv365136,264,732 - 136,273,251 (+)NCBImm8
Celera5132,991,486 - 133,024,448 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.62NCBI
Zp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21220,690,547 - 20,697,513 (-)NCBI
Rnor_6.0 Ensembl1223,735,223 - 23,742,190 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01223,735,225 - 23,752,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01225,733,873 - 25,740,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41221,805,746 - 21,812,711 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11221,792,837 - 21,799,583 (-)NCBI
Celera1222,453,873 - 22,460,838 (-)NCBICelera
Cytogenetic Map12q12NCBI
Zp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545615,013,472 - 15,020,809 (+)NCBIChiLan1.0ChiLan1.0
ZP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1782,872,676 - 82,891,655 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl782,844,162 - 82,891,655 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0767,574,932 - 67,592,757 (-)NCBIMhudiblu_PPA_v0panPan3
ZP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,586,212 - 7,594,610 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl67,585,970 - 7,594,610 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha69,281,828 - 9,290,191 (+)NCBI
ROS_Cfam_1.067,406,839 - 7,415,182 (+)NCBI
UMICH_Zoey_3.167,375,722 - 7,384,085 (+)NCBI
UNSW_CanFamBas_1.067,338,676 - 7,347,061 (+)NCBI
UU_Cfam_GSD_1.067,501,843 - 7,510,213 (+)NCBI
Zp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,014,297 - 132,023,299 (+)NCBI
SpeTri2.0NW_0049365432,013,231 - 2,022,270 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZP3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12810,534,383 - 10,579,828 (+)NCBI
ChlSab1.1 Ensembl2810,562,455 - 10,579,825 (+)Ensembl
Zp3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474015,037,818 - 15,044,207 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system reproductive system respiratory system
High
Medium 2 1 2 1
Low 1 1 3 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000008432   ⟹   ENSSSCP00000008213
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl39,934,761 - 9,944,941 (-)Ensembl
RefSeq Acc Id: NM_213893   ⟹   NP_999058
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.139,934,760 - 9,944,924 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999058 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA31145 (Get FASTA)   NCBI Sequence Viewer  
  BAA08093 (Get FASTA)   NCBI Sequence Viewer  
  P42098 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_999058   ⟸   NM_213893
- Peptide Label: precursor
- UniProtKB: P42098 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000008213   ⟸   ENSSSCT00000008432
Protein Domains
ZP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007691 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070017658 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000008213 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070029142 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008432 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070034870 UniProtKB/TrEMBL
InterPro ZP3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP_dom_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396927 UniProtKB/Swiss-Prot
NCBI Gene ZP3 ENTREZGENE
PANTHER PTHR11576:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Zona_pellucida UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ZPELLUCIDA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00241 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1ULX1_PIG UniProtKB/TrEMBL
  F1RKE0_PIG UniProtKB/TrEMBL
  P42098 ENTREZGENE, UniProtKB/Swiss-Prot