MIR219B (microRNA mir-219b) - Rat Genome Database

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Gene: MIR219B (microRNA mir-219b) Sus scrofa
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Symbol: MIR219B (Ensembl: MIR219A2)
Name: microRNA mir-219b (Ensembl:microRNA 219a-2)
RGD ID: 14041205
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 219b; ssc-mir-219b
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,816,961 - 268,817,057 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,816,967 - 268,817,050 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,806,853 - 302,806,936 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:24499489  


Genomics

Comparative Map Data
MIR219B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,816,961 - 268,817,057 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,816,967 - 268,817,050 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,806,853 - 302,806,936 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIR219A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,392,618 - 128,392,714 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,392,618 - 128,392,714 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,154,897 - 131,154,993 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,194,717 - 130,194,813 (-)NCBINCBI36Build 36hg18NCBI36
Celera9101,805,800 - 101,805,896 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,767,720 - 100,767,816 (-)NCBIHuRef
CHM1_19131,305,922 - 131,306,018 (-)NCBICHM1_1
T2T-CHM13v2.09140,599,720 - 140,599,816 (-)NCBIT2T-CHM13v2.0
Mir219a-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,735,643 - 29,735,739 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl229,735,643 - 29,735,739 (-)EnsemblGRCm39 Ensembl
GRCm38229,845,631 - 29,845,727 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl229,845,631 - 29,845,727 (-)EnsemblGRCm38mm10GRCm38
MGSCv37229,701,151 - 29,701,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera229,552,725 - 29,552,821 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map220.72NCBI
MIR219-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,139,107 - 55,139,171 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,139,107 - 55,139,171 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,334,083 - 54,334,147 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,061,208 - 56,061,272 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,061,208 - 56,061,272 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,820,802 - 54,820,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,135,067 - 55,135,131 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,226,958 - 55,227,022 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in MIR219B
1 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system
High
Medium 6
Low 8
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000028795
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1268,816,961 - 268,817,057 (-)Ensembl
RefSeq Acc Id: NR_128560
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11268,816,967 - 268,817,050 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000027037 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000028795 ENTREZGENE
miRBase MI0031642 ENTREZGENE
NCBI Gene MIR219B ENTREZGENE
RNAcentral URS00007E45F4 RNACentral
  URS00007E476F RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR219B  microRNA mir-219b    microRNA 219b  Symbol and/or name change 5135510 APPROVED