RYBP (RING1 and YY1 binding protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: RYBP (RING1 and YY1 binding protein) Sus scrofa
Analyze
Symbol: RYBP
Name: RING1 and YY1 binding protein
RGD ID: 14035331
Description: ENCODES a protein that exhibits nucleic acid binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); PcG protein complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RING1 and YY1-binding protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1353,724,065 - 53,809,601 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11353,724,062 - 53,809,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21359,462,871 - 59,523,645 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IBA,IEA)
PcG protein complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RYBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1353,724,065 - 53,809,601 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11353,724,062 - 53,809,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21359,462,871 - 59,523,645 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RYBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38372,374,597 - 72,446,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl372,371,825 - 72,446,621 (-)EnsemblGRCh38hg38GRCh38
GRCh37372,423,744 - 72,495,774 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36372,506,438 - 72,578,462 (-)NCBINCBI36Build 36hg18NCBI36
Build 34372,508,773 - 72,578,464NCBI
Celera372,354,609 - 72,427,714 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef372,426,405 - 72,499,331 (-)NCBIHuRef
CHM1_1372,375,955 - 72,448,623 (-)NCBICHM1_1
T2T-CHM13v2.0372,416,169 - 72,500,475 (-)NCBIT2T-CHM13v2.0
Rybp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396100,205,526 - 100,264,319 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6100,205,526 - 100,264,446 (-)EnsemblGRCm39 Ensembl
GRCm386100,228,565 - 100,287,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6100,228,565 - 100,287,485 (-)EnsemblGRCm38mm10GRCm38
MGSCv376100,178,559 - 100,237,352 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366100,194,028 - 100,252,821 (-)NCBIMGSCv36mm8
Celera6102,093,266 - 102,151,363 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map646.62NCBI
Rybp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84134,432,663 - 134,484,732 (-)NCBIGRCr8
mRatBN7.24132,876,260 - 132,928,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4132,876,361 - 132,928,316 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4138,290,334 - 138,342,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04134,071,106 - 134,123,179 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04132,689,373 - 132,741,452 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04132,689,623 - 132,740,823 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4132,689,531 - 132,740,938 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04197,177,356 - 197,228,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44135,101,700 - 135,153,427 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14135,346,439 - 135,400,411 (-)NCBI
Celera4121,729,359 - 121,780,574 (-)NCBICelera
Cytogenetic Map4q34NCBI
Rybp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542115,728,580 - 15,803,150 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542115,728,778 - 15,803,150 (+)NCBIChiLan1.0ChiLan1.0
RYBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2272,330,724 - 72,404,552 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1372,335,512 - 72,409,340 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0372,315,494 - 72,389,328 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1374,244,030 - 74,319,460 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl374,247,807 - 74,318,398 (-)Ensemblpanpan1.1panPan2
RYBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12019,650,936 - 19,732,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2019,615,426 - 19,729,474 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2019,631,461 - 19,711,420 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02019,688,765 - 19,768,997 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12019,375,120 - 19,455,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02019,717,116 - 19,793,847 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02019,789,496 - 19,869,686 (+)NCBIUU_Cfam_GSD_1.0
Rybp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049423,618,715 - 3,693,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366033,618,795 - 3,690,410 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366033,618,715 - 3,693,007 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12233,327,516 - 33,397,463 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2233,331,290 - 33,397,362 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041133,371,297 - 133,441,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rybp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247736,899,927 - 6,993,526 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247736,899,927 - 6,993,434 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RYBP
1817 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 1 5 15 3 2
Low 1 2 2 2 8 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024414   ⟹   ENSSSCP00000022280
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1353,724,065 - 53,809,601 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000064819   ⟹   ENSSSCP00000041824
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1353,724,065 - 53,809,403 (-)Ensembl
RefSeq Acc Id: XM_021069217   ⟹   XP_020924876
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11353,724,062 - 53,809,698 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020924876   ⟸   XM_021069217
- UniProtKB: A0A4X1V9X9 (UniProtKB/TrEMBL),   F1SFN1 (UniProtKB/TrEMBL),   A0A8D0NAM9 (UniProtKB/TrEMBL),   A0A8D0LLJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000041824   ⟸   ENSSSCT00000064819
RefSeq Acc Id: ENSSSCP00000022280   ⟸   ENSSSCT00000024414
Protein Domains
RanBP2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005018223 UniProtKB/TrEMBL
  ENSSSCG00015029080 UniProtKB/TrEMBL
  ENSSSCG00025057802 UniProtKB/TrEMBL
  ENSSSCG00030024519 UniProtKB/TrEMBL
  ENSSSCG00035070034 UniProtKB/TrEMBL
  ENSSSCG00040038375 UniProtKB/TrEMBL
  ENSSSCG00045027987 UniProtKB/TrEMBL
  ENSSSCG00050040111 UniProtKB/TrEMBL
  ENSSSCG00055012708 UniProtKB/TrEMBL
  ENSSSCG00060053031 UniProtKB/TrEMBL
  ENSSSCG00065029227 UniProtKB/TrEMBL
  ENSSSCG00070022713 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024414 ENTREZGENE
  ENSSSCT00000024414.4 UniProtKB/TrEMBL
  ENSSSCT00000064819.3 UniProtKB/TrEMBL
  ENSSSCT00005028810.1 UniProtKB/TrEMBL
  ENSSSCT00005028850.1 UniProtKB/TrEMBL
  ENSSSCT00015038683.1 UniProtKB/TrEMBL
  ENSSSCT00025079104.1 UniProtKB/TrEMBL
  ENSSSCT00030034160.1 UniProtKB/TrEMBL
  ENSSSCT00030034168.1 UniProtKB/TrEMBL
  ENSSSCT00030034172.1 UniProtKB/TrEMBL
  ENSSSCT00035094593.1 UniProtKB/TrEMBL
  ENSSSCT00035094602.1 UniProtKB/TrEMBL
  ENSSSCT00035094614.1 UniProtKB/TrEMBL
  ENSSSCT00040051323.1 UniProtKB/TrEMBL
  ENSSSCT00045047654.1 UniProtKB/TrEMBL
  ENSSSCT00050054240.1 UniProtKB/TrEMBL
  ENSSSCT00055024994.1 UniProtKB/TrEMBL
  ENSSSCT00060072194.1 UniProtKB/TrEMBL
  ENSSSCT00065039437.1 UniProtKB/TrEMBL
  ENSSSCT00070045160.1 UniProtKB/TrEMBL
Gene3D-CATH Zinc finger, RanBP2-type UniProtKB/TrEMBL
InterPro RYBP/YAF2 UniProtKB/TrEMBL
  YAF2_RYBP UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
NCBI Gene RYBP ENTREZGENE
PANTHER PTHR12920 UniProtKB/TrEMBL
  RING1 AND YY1-BINDING PROTEIN UniProtKB/TrEMBL
Pfam YAF2_RYBP UniProtKB/TrEMBL
  zf-RanBP UniProtKB/TrEMBL
PROSITE ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP SSF90209 UniProtKB/TrEMBL
UniProt A0A287AD58_PIG UniProtKB/TrEMBL
  A0A4X1V9X9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0J2T3_PIG UniProtKB/TrEMBL
  A0A8D0LLJ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NAM9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W3J6_PIG UniProtKB/TrEMBL
  A0A8D1B1Z5_PIG UniProtKB/TrEMBL
  A0A8D1B845_PIG UniProtKB/TrEMBL
  F1SFN1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92532 ENTREZGENE