BAZ2B (bromodomain adjacent to zinc finger domain 2B) - Rat Genome Database

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Gene: BAZ2B (bromodomain adjacent to zinc finger domain 2B) Sus scrofa
Analyze
Symbol: BAZ2B
Name: bromodomain adjacent to zinc finger domain 2B
RGD ID: 14034888
Description: ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); INVOLVED IN snRNA 3'-end processing (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN integrator complex (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bromodomain adjacent to zinc finger domain protein 2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1566,254,948 - 66,571,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11566,254,888 - 66,411,261 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21573,484,177 - 73,887,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
integrator complex  (IBA,IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
BAZ2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1566,254,948 - 66,571,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11566,254,888 - 66,411,261 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21573,484,177 - 73,887,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BAZ2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382159,315,312 - 159,712,442 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2159,318,979 - 159,616,569 (-)EnsemblGRCh38hg38GRCh38
GRCh372160,175,490 - 160,568,953 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362159,883,736 - 160,181,305 (-)NCBINCBI36Build 36hg18NCBI36
Build 342160,000,998 - 160,128,996NCBI
Celera2153,787,429 - 154,084,921 (-)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2152,059,204 - 152,356,919 (-)NCBIHuRef
CHM1_12160,181,389 - 160,479,489 (-)NCBICHM1_1
T2T-CHM13v2.02159,772,618 - 160,169,805 (-)NCBIT2T-CHM13v2.0
Baz2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39259,729,707 - 60,040,243 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl259,729,707 - 60,040,183 (-)EnsemblGRCm39 Ensembl
GRCm38259,899,363 - 60,209,913 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl259,899,363 - 60,209,839 (-)EnsemblGRCm38mm10GRCm38
MGSCv37259,737,420 - 59,963,797 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36259,700,202 - 59,926,579 (-)NCBIMGSCv36mm8
Celera261,594,999 - 61,820,803 (-)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map234.18NCBI
Baz2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8364,792,984 - 65,034,547 (-)NCBIGRCr8
mRatBN7.2344,384,282 - 44,681,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl344,385,474 - 44,592,908 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx347,741,609 - 47,982,579 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0356,325,177 - 56,566,158 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0354,095,287 - 54,335,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0345,968,845 - 46,286,915 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl345,968,825 - 46,153,371 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0351,196,815 - 51,338,843 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0351,081,857 - 51,162,796 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4341,617,500 - 41,859,791 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1341,512,679 - 41,617,013 (-)NCBI
Celera342,430,535 - 42,670,212 (-)NCBICelera
Cytogenetic Map3q21NCBI
Baz2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544914,140,699 - 14,276,933 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544914,008,538 - 14,278,227 (+)NCBIChiLan1.0ChiLan1.0
BAZ2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21362,004,430 - 62,403,627 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B62,015,782 - 62,418,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B46,604,986 - 46,929,050 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B163,976,008 - 164,377,473 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B163,980,886 - 164,146,146 (-)Ensemblpanpan1.1panPan2
BAZ2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1365,083,273 - 5,306,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl365,086,530 - 5,479,813 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha365,224,284 - 5,517,073 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0365,207,998 - 5,501,122 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl365,209,210 - 5,384,509 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1365,226,159 - 5,519,092 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0365,268,761 - 5,561,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0365,311,475 - 5,604,664 (-)NCBIUU_Cfam_GSD_1.0
Baz2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303122,254,131 - 122,600,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646919,224,475 - 19,362,346 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646919,106,421 - 19,363,668 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAZ2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11044,703,711 - 45,029,751 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1044,700,082 - 44,962,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040154,459,304 - 154,866,209 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Baz2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247326,087,726 - 6,344,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247325,928,127 - 6,344,173 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BAZ2B
2733 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 1 23 2 3 3
Low 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017293   ⟹   ENSSSCP00000016830
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1566,255,135 - 66,571,077 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000044120   ⟹   ENSSSCP00000056972
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1566,254,948 - 66,571,047 (-)Ensembl
RefSeq Acc Id: XM_021074758   ⟹   XP_020930417
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11566,254,888 - 66,411,261 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020930417 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AGF25298 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000016830
  ENSSSCP00000016830.4
  ENSSSCP00000056972.2
  ENSSSCP00025014994.1
  ENSSSCP00035003124.1
  ENSSSCP00045044516.1
  ENSSSCP00055024975.1
Reference Protein Sequences
RefSeq Acc Id: XP_020930417   ⟸   XM_021074758
- UniProtKB: A0A8D0RDP1 (UniProtKB/TrEMBL),   A0A8D0YLA7 (UniProtKB/TrEMBL),   F1RPS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000056972   ⟸   ENSSSCT00000044120
RefSeq Acc Id: ENSSSCP00000016830   ⟸   ENSSSCT00000017293
Protein Domains
Bromo   DDT   MBD   PHD-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015882 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025025610 UniProtKB/TrEMBL
  ENSSSCG00035007439 UniProtKB/TrEMBL
  ENSSSCG00045036261 UniProtKB/TrEMBL
  ENSSSCG00055015651 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017293 ENTREZGENE
  ENSSSCT00000017293.5 UniProtKB/TrEMBL
  ENSSSCT00000044120.2 UniProtKB/TrEMBL
  ENSSSCT00025035909.1 UniProtKB/TrEMBL
  ENSSSCT00035009286.1 UniProtKB/TrEMBL
  ENSSSCT00045063141.1 UniProtKB/TrEMBL
  ENSSSCT00055031371.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro BAZ2A/B_Bromo UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  DDT_dom UniProtKB/TrEMBL
  DNA-bd_dom_sf UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
  WHIM2_dom UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene BAZ2B ENTREZGENE
PANTHER BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN 2B UniProtKB/TrEMBL
  BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B UniProtKB/TrEMBL
  NUCLEAR FACTOR-RELATED UniProtKB/TrEMBL
  TRANSCRIPTION INTERMEDIARY FACTOR UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  MBD UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  WSD UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  MBD UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  MBD UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/TrEMBL
  SSF54171 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A287BKD3_PIG UniProtKB/TrEMBL
  A0A8D0RDP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YLA7 ENTREZGENE, UniProtKB/TrEMBL
  F1RPS2 ENTREZGENE, UniProtKB/TrEMBL
  M1KDZ5_PIG UniProtKB/TrEMBL