NET1 (neuroepithelial cell transforming 1) - Rat Genome Database

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Gene: NET1 (neuroepithelial cell transforming 1) Sus scrofa
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Symbol: NET1
Name: neuroepithelial cell transforming 1
RGD ID: 14034051
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN myoblast migration (ortholog); positive regulation of substrate adhesion-dependent cell spreading (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); high grade glioma (ortholog); FOUND IN nucleus (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1065,425,011 - 65,459,754 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11065,428,013 - 65,438,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,541,976 - 71,577,001 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (ISO)
plasma membrane  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NET1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1065,425,011 - 65,459,754 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11065,428,013 - 65,438,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,541,976 - 71,577,001 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NET1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38105,412,557 - 5,459,056 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl105,412,557 - 5,459,056 (+)EnsemblGRCh38hg38GRCh38
GRCh37105,454,520 - 5,501,019 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36105,444,518 - 5,490,426 (+)NCBINCBI36Build 36hg18NCBI36
Build 34105,478,582 - 5,490,401NCBI
Celera105,385,186 - 5,430,983 (+)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef105,383,734 - 5,430,137 (+)NCBIHuRef
CHM1_1105,454,522 - 5,500,985 (+)NCBICHM1_1
T2T-CHM13v2.0105,415,941 - 5,462,403 (+)NCBIT2T-CHM13v2.0
Net1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,932,018 - 3,968,220 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,932,018 - 3,968,220 (-)EnsemblGRCm39 Ensembl
GRCm38133,882,018 - 3,918,220 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,882,018 - 3,918,220 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,881,807 - 3,917,466 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,882,582 - 3,917,357 (-)NCBIMGSCv36mm8
Celera133,867,365 - 3,905,036 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map132.17NCBI
Net1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,251,145 - 71,280,345 (+)NCBIGRCr8
mRatBN7.21766,341,251 - 66,370,445 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,340,728 - 66,370,441 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1769,834,187 - 69,844,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01773,663,012 - 73,673,088 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01767,706,009 - 67,716,085 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01769,991,786 - 70,020,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1770,010,794 - 70,020,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,695,341 - 71,724,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,533,225 - 77,543,337 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,525,117 - 77,552,726 (+)NCBI
Celera1765,866,059 - 65,876,167 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
Net1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542122,105,257 - 22,156,292 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542122,105,292 - 22,154,368 (+)NCBIChiLan1.0ChiLan1.0
NET1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,969,380 - 18,014,733 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,974,701 - 18,019,310 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,457,920 - 5,503,223 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1105,444,213 - 5,489,509 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl105,444,127 - 5,489,509 (+)Ensemblpanpan1.1panPan2
NET1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1230,450,946 - 30,463,280 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl230,450,965 - 30,492,074 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,480,707 - 27,541,903 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0230,832,019 - 30,844,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl230,830,531 - 30,892,820 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1227,926,665 - 27,988,941 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,764,938 - 28,826,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,481,270 - 29,543,633 (-)NCBIUU_Cfam_GSD_1.0
Net1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934432,862,324 - 32,891,380 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364849,027,515 - 9,056,600 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364849,027,515 - 9,056,571 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NET1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.195,547,275 - 5,579,006 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl95,567,225 - 5,577,539 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605110,789,221 - 10,834,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Net1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624775224,297 - 262,630 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624775223,832 - 260,623 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NET1
363 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 3 3 5 2 14 2 3 3
Low 1 9
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000029208   ⟹   ENSSSCP00000024193
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1065,426,519 - 65,459,422 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000053439   ⟹   ENSSSCP00000052015
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1065,426,519 - 65,459,754 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076096   ⟹   ENSSSCP00000068315
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1065,425,011 - 65,438,354 (-)Ensembl
RefSeq Acc Id: XM_003130825   ⟹   XP_003130873
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11065,428,013 - 65,438,346 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003130873 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000024193.3
  ENSSSCP00000052015.2
  ENSSSCP00000068315
  ENSSSCP00000068315.1
  ENSSSCP00040012036.1
RefSeq Acc Id: XP_003130873   ⟸   XM_003130825
- UniProtKB: A0A480L6U2 (UniProtKB/TrEMBL),   A0A8D1DSK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000024193   ⟸   ENSSSCT00000029208
RefSeq Acc Id: ENSSSCP00000068315   ⟸   ENSSSCT00000076096
RefSeq Acc Id: ENSSSCP00000052015   ⟸   ENSSSCT00000053439
Protein Domains
DH   PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000023105 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040021307 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000029208.4 UniProtKB/TrEMBL
  ENSSSCT00000053439.3 UniProtKB/TrEMBL
  ENSSSCT00000076096 ENTREZGENE
  ENSSSCT00000076096.2 UniProtKB/TrEMBL
  ENSSSCT00040028671.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  GDS_CDC24_CS UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report ssc:100516825 UniProtKB/TrEMBL
NCBI Gene NET1 ENTREZGENE
PANTHER NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PROSITE DH_1 UniProtKB/TrEMBL
  DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
UniProt A0A287B7D4_PIG UniProtKB/TrEMBL
  A0A480L6U2 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QVZ1_PIG UniProtKB/TrEMBL
  A0A8D1DSK2 ENTREZGENE, UniProtKB/TrEMBL
  I3LJD3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95622 ENTREZGENE