COMP (cartilage oligomeric matrix protein) - Rat Genome Database

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Gene: COMP (cartilage oligomeric matrix protein) Sus scrofa
Analyze
Symbol: COMP
Name: cartilage oligomeric matrix protein
RGD ID: 14032705
Description: ENCODES a protein that exhibits extracellular matrix structural constituent (ortholog); fibronectin binding (ortholog); vitamin D binding (ortholog); INVOLVED IN apoptotic process (ortholog); artery morphogenesis (ortholog); blood coagulation (ortholog); ASSOCIATED WITH carpal tunnel syndrome 2 (ortholog); connective tissue disease (ortholog); genetic disease (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative cartilage oligomeric matrix protein
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,061,426 - 59,069,564 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,061,409 - 59,068,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,815,756 - 58,823,293 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
COMP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,061,426 - 59,069,564 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,061,409 - 59,068,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,815,756 - 58,823,293 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COMP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,782,773 - 18,791,305 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,782,773 - 18,791,305 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,893,583 - 18,902,114 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,754,583 - 18,763,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,754,583 - 18,763,114NCBI
Celera1918,798,378 - 18,806,909 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,458,025 - 18,466,569 (-)NCBIHuRef
CHM1_11918,893,587 - 18,902,107 (-)NCBICHM1_1
T2T-CHM13v2.01918,918,369 - 18,926,902 (-)NCBIT2T-CHM13v2.0
Comp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,826,186 - 70,834,721 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,826,208 - 70,834,716 (+)EnsemblGRCm39 Ensembl
GRCm38870,373,548 - 70,382,066 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,373,558 - 70,382,066 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,897,447 - 72,905,965 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,302,547 - 73,311,055 (+)NCBIMGSCv36mm8
Celera872,929,973 - 72,938,489 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Comp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,081,172 - 19,089,548 (-)NCBIGRCr8
mRatBN7.21619,047,206 - 19,055,584 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,047,207 - 19,055,845 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,086,958 - 19,095,161 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,219,417 - 20,227,820 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,139,921 - 19,148,124 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,798,437 - 20,807,070 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,798,437 - 20,807,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,647,382 - 20,657,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1619,237,609 - 19,245,998 (-)NCBICelera
Cytogenetic Map16p14NCBI
COMP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,643,332 - 23,652,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,651,519 - 22,661,150 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,222,270 - 18,230,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,229,420 - 19,238,053 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,229,562 - 19,238,008 (-)Ensemblpanpan1.1panPan2
COMP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,306,813 - 44,314,575 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,306,859 - 44,314,625 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,221,457 - 44,229,145 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,793,007 - 44,800,779 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,793,063 - 44,800,711 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,030,270 - 44,038,042 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,440,677 - 44,448,355 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,715,955 - 44,723,648 (+)NCBIUU_Cfam_GSD_1.0
Comp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,995,236 - 203,002,126 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,544,389 - 2,551,164 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,544,389 - 2,551,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COMP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,246,617 - 17,255,561 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,246,762 - 17,255,126 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,070,833 - 2,079,420 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Comp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,871,002 - 1,877,369 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,870,975 - 1,877,434 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COMP
86 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
mesenchyme
mesoderm
nervous system
renal system
reproductive system
2 11 3 2 11 1 2

Sequence


Ensembl Acc Id: ENSSSCT00000015202   ⟹   ENSSSCP00000014796
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl259,061,426 - 59,069,564 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000077413   ⟹   ENSSSCP00000065849
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl259,061,426 - 59,069,564 (+)Ensembl
RefSeq Acc Id: XM_003123527   ⟹   XP_003123575
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1259,061,409 - 59,068,951 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003123575   ⟸   XM_003123527
- UniProtKB: F1S902 (UniProtKB/TrEMBL),   A0A4X1U7X9 (UniProtKB/TrEMBL),   A0A8D1U7D8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000014796   ⟸   ENSSSCT00000015202
Ensembl Acc Id: ENSSSCP00000065849   ⟸   ENSSSCT00000077413
Protein Domains
EGF-like   TSP C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013916 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015056764 UniProtKB/TrEMBL
  ENSSSCG00025034191 UniProtKB/TrEMBL
  ENSSSCG00030045325 UniProtKB/TrEMBL
  ENSSSCG00035069449 UniProtKB/TrEMBL
  ENSSSCG00040060450 UniProtKB/TrEMBL
  ENSSSCG00045028017 UniProtKB/TrEMBL
  ENSSSCG00050062381 UniProtKB/TrEMBL
  ENSSSCG00055020827 UniProtKB/TrEMBL
  ENSSSCG00060040469 UniProtKB/TrEMBL
  ENSSSCG00065025469 UniProtKB/TrEMBL
  ENSSSCG00070014665 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015202 ENTREZGENE
  ENSSSCT00000015202.5 UniProtKB/TrEMBL
  ENSSSCT00000077413.2 UniProtKB/TrEMBL
  ENSSSCT00015075785.1 UniProtKB/TrEMBL
  ENSSSCT00015075870.1 UniProtKB/TrEMBL
  ENSSSCT00015075983.1 UniProtKB/TrEMBL
  ENSSSCT00025046670.1 UniProtKB/TrEMBL
  ENSSSCT00025046728.1 UniProtKB/TrEMBL
  ENSSSCT00025046785.1 UniProtKB/TrEMBL
  ENSSSCT00030063278.1 UniProtKB/TrEMBL
  ENSSSCT00030063315.1 UniProtKB/TrEMBL
  ENSSSCT00035093807.1 UniProtKB/TrEMBL
  ENSSSCT00035093849.1 UniProtKB/TrEMBL
  ENSSSCT00040082495.1 UniProtKB/TrEMBL
  ENSSSCT00040082682.1 UniProtKB/TrEMBL
  ENSSSCT00040082949.1 UniProtKB/TrEMBL
  ENSSSCT00045047833.1 UniProtKB/TrEMBL
  ENSSSCT00045047997.1 UniProtKB/TrEMBL
  ENSSSCT00050084974.1 UniProtKB/TrEMBL
  ENSSSCT00050084976.1 UniProtKB/TrEMBL
  ENSSSCT00055040915.1 UniProtKB/TrEMBL
  ENSSSCT00055041021.1 UniProtKB/TrEMBL
  ENSSSCT00060054810.1 UniProtKB/TrEMBL
  ENSSSCT00060054814.1 UniProtKB/TrEMBL
  ENSSSCT00060054843.1 UniProtKB/TrEMBL
  ENSSSCT00065034084.1 UniProtKB/TrEMBL
  ENSSSCT00065034088.1 UniProtKB/TrEMBL
  ENSSSCT00065034101.1 UniProtKB/TrEMBL
  ENSSSCT00070028777.1 UniProtKB/TrEMBL
  ENSSSCT00070028788.1 UniProtKB/TrEMBL
  ENSSSCT00070028801.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.10 UniProtKB/TrEMBL
  2.60.120.200 UniProtKB/TrEMBL
  4.10.1080.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
  Thbs/COMP_coiled-coil UniProtKB/TrEMBL
  Thrombospondin_3-like_rpt UniProtKB/TrEMBL
  Thrombospondin_3_rpt UniProtKB/TrEMBL
  Thrombospondin_C UniProtKB/TrEMBL
  TSP-5_cc UniProtKB/TrEMBL
  TSP/COMP_coiled-coil_sf UniProtKB/TrEMBL
  TSP_type-3_rpt UniProtKB/TrEMBL
KEGG Report ssc:396554 UniProtKB/TrEMBL
NCBI Gene COMP ENTREZGENE
PANTHER PTHR10199:SF88 UniProtKB/TrEMBL
  THROMBOSPONDIN UniProtKB/TrEMBL
Pfam COMP UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  TSP_3 UniProtKB/TrEMBL
  TSP_C UniProtKB/TrEMBL
PROSITE EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  TSP3 UniProtKB/TrEMBL
  TSP_CTER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP Assembly domain of cartilage oligomeric matrix protein UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  SSF103647 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A4X1U2P9_PIG UniProtKB/TrEMBL
  A0A4X1U589_PIG UniProtKB/TrEMBL
  A0A4X1U7X9 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QMI2_PIG UniProtKB/TrEMBL
  A0A8D1RCD0_PIG UniProtKB/TrEMBL
  A0A8D1U7D8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2BJ94_PIG UniProtKB/TrEMBL
  F1S902 ENTREZGENE, UniProtKB/TrEMBL
  Q866A6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86892 ENTREZGENE