MFSD1 (major facilitator superfamily domain containing 1) - Rat Genome Database

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Gene: MFSD1 (major facilitator superfamily domain containing 1) Sus scrofa
Analyze
Symbol: MFSD1
Name: major facilitator superfamily domain containing 1
RGD ID: 14032601
Description: ENCODES a protein that exhibits dipeptide uniporter activity (inferred); protein homodimerization activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN dipeptide transmembrane transport (inferred); dipeptide transmembrane transport from lysosomal lumen to cytosol (inferred); protein localization to lysosome (inferred); FOUND IN lysosomal membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: major facilitator superfamily domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1398,592,370 - 98,615,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11398,592,344 - 98,615,061 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213107,004,118 - 107,049,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
lysosomal membrane  (IEA,ISO)
lysosome  (IBA,IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MFSD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1398,592,370 - 98,615,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11398,592,344 - 98,615,061 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213107,004,118 - 107,049,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFSD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383158,802,054 - 158,829,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3158,732,198 - 158,829,719 (+)EnsemblGRCh38hg38GRCh38
GRCh373158,519,843 - 158,547,505 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363160,002,606 - 160,030,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 343160,002,613 - 160,030,206NCBI
Celera3156,942,471 - 156,970,268 (+)NCBICelera
Cytogenetic Map3q25.32NCBI
HuRef3155,915,581 - 155,943,367 (+)NCBIHuRef
CHM1_13158,482,624 - 158,510,416 (+)NCBICHM1_1
T2T-CHM13v2.03161,575,980 - 161,603,601 (+)NCBIT2T-CHM13v2.0
Mfsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39367,490,101 - 67,511,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl367,490,074 - 67,511,570 (+)EnsemblGRCm39 Ensembl
GRCm38367,582,768 - 67,604,231 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl367,582,741 - 67,604,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv37367,386,690 - 67,408,153 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36367,670,697 - 67,692,160 (+)NCBIMGSCv36mm8
Celera367,709,416 - 67,730,879 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map331.07NCBI
Mfsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82154,156,167 - 154,176,209 (+)NCBIGRCr8
mRatBN7.22151,846,130 - 151,866,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2151,846,146 - 151,867,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2158,963,053 - 158,983,289 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02157,013,548 - 157,033,784 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02151,646,296 - 151,666,532 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02164,747,655 - 164,767,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2164,747,677 - 164,767,682 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02184,095,514 - 184,115,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42157,432,951 - 157,452,956 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12157,382,939 - 157,400,624 (+)NCBI
Celera2146,215,790 - 146,235,853 (+)NCBICelera
Cytogenetic Map2q32NCBI
Mfsd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554489,536,549 - 9,561,661 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554489,536,613 - 9,557,846 (+)NCBIChiLan1.0ChiLan1.0
MFSD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,742,121 - 156,818,814 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13156,679,244 - 156,820,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03155,758,133 - 155,899,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13163,878,611 - 163,946,103 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3163,878,833 - 163,903,955 (+)Ensemblpanpan1.1panPan2
MFSD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13425,069,701 - 25,094,196 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3425,069,696 - 25,092,386 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3429,159,099 - 29,183,659 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03425,012,255 - 25,036,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3425,012,238 - 25,036,848 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13425,050,102 - 25,074,425 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03425,012,792 - 25,037,357 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03425,255,267 - 25,279,836 (+)NCBIUU_Cfam_GSD_1.0
Mfsd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560284,321,103 - 84,341,152 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365195,392,777 - 5,412,856 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365195,392,820 - 5,412,847 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFSD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11531,995,285 - 32,043,708 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1532,016,368 - 32,043,586 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660414,579,860 - 4,607,106 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mfsd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473036,502,209 - 36,525,748 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473036,502,186 - 36,525,331 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MFSD1
718 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000026649   ⟹   ENSSSCP00000023961
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1398,592,389 - 98,615,523 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000074826   ⟹   ENSSSCP00000063173
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1398,592,455 - 98,615,053 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000077669   ⟹   ENSSSCP00000063761
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1398,592,374 - 98,615,098 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000085365   ⟹   ENSSSCP00000072023
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1398,592,370 - 98,615,058 (+)Ensembl
RefSeq Acc Id: XM_003358650   ⟹   XP_003358698
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11398,592,345 - 98,615,061 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069724   ⟹   XP_020925383
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11398,592,344 - 98,613,494 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020925383   ⟸   XM_021069724
- Peptide Label: isoform X2
- UniProtKB: A0A8D1L3C4 (UniProtKB/TrEMBL),   K9J4U7 (UniProtKB/TrEMBL),   I3LIQ5 (UniProtKB/TrEMBL),   A0A4X1SGM9 (UniProtKB/TrEMBL),   A0A8D0PWS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003358698   ⟸   XM_003358650
- Peptide Label: isoform X1
- UniProtKB: I3LIQ5 (UniProtKB/TrEMBL),   A0A8D1L3C4 (UniProtKB/TrEMBL),   K9J4U7 (UniProtKB/TrEMBL),   A0A4X1SGM9 (UniProtKB/TrEMBL),   A0A8D0PWS7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000023961   ⟸   ENSSSCT00000026649
Ensembl Acc Id: ENSSSCP00000072023   ⟸   ENSSSCT00000085365
Ensembl Acc Id: ENSSSCP00000063173   ⟸   ENSSSCT00000074826
Ensembl Acc Id: ENSSSCP00000063761   ⟸   ENSSSCT00000077669

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015072947 UniProtKB/TrEMBL
  ENSSSCG00025031562 UniProtKB/TrEMBL
  ENSSSCG00030010405 UniProtKB/TrEMBL
  ENSSSCG00035059611 UniProtKB/TrEMBL
  ENSSSCG00040012204 UniProtKB/TrEMBL
  ENSSSCG00045026455 UniProtKB/TrEMBL
  ENSSSCG00060030944 UniProtKB/TrEMBL
  ENSSSCG00065037077 UniProtKB/TrEMBL
  ENSSSCG00070000712 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026649 ENTREZGENE
  ENSSSCT00000026649.2 UniProtKB/TrEMBL
  ENSSSCT00000074826.1 UniProtKB/TrEMBL
  ENSSSCT00000077669.2 UniProtKB/TrEMBL
  ENSSSCT00000085365 ENTREZGENE
  ENSSSCT00000085365.1 UniProtKB/TrEMBL
  ENSSSCT00015098113.1 UniProtKB/TrEMBL
  ENSSSCT00025042956.1 UniProtKB/TrEMBL
  ENSSSCT00030014285.1 UniProtKB/TrEMBL
  ENSSSCT00035079913.1 UniProtKB/TrEMBL
  ENSSSCT00040016059.1 UniProtKB/TrEMBL
  ENSSSCT00045045202.1 UniProtKB/TrEMBL
  ENSSSCT00060041888.1 UniProtKB/TrEMBL
  ENSSSCT00065050586.1 UniProtKB/TrEMBL
  ENSSSCT00070001352.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  MFSD1 UniProtKB/TrEMBL
KEGG Report ssc:100621077 UniProtKB/TrEMBL
NCBI Gene MFSD1 ENTREZGENE
PANTHER MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A4X1SGM9 ENTREZGENE
  A0A5G2QG03_PIG UniProtKB/TrEMBL
  A0A5G2QIM7_PIG UniProtKB/TrEMBL
  A0A8D0PWS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1L3C4 ENTREZGENE, UniProtKB/TrEMBL
  I3LIQ5 ENTREZGENE, UniProtKB/TrEMBL
  K9J4U7 ENTREZGENE
UniProt Secondary K9J4U7 UniProtKB/TrEMBL
VGNC ID VGNC:90182 ENTREZGENE