MIR135-1 (microRNA mir-135-1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MIR135-1 (microRNA mir-135-1) Sus scrofa
Analyze
Symbol: MIR135-1 (Ensembl: ssc-mir-135-1)
Name: microRNA mir-135-1 (Ensembl:ssc-mir-135-1)
RGD ID: 14032391
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 135-1; ssc-mir-135-1
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,441,079 - 34,441,168 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,441,079 - 34,441,168 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,564,051 - 37,564,140 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:21312241  


Genomics

Comparative Map Data
MIR135-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,441,079 - 34,441,168 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,441,079 - 34,441,168 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,564,051 - 37,564,140 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MIR135A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,294,219 - 52,294,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,294,219 - 52,294,308 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,328,235 - 52,328,324 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,303,274 - 52,303,363 (-)NCBINCBI36Build 36hg18NCBI36
Celera352,307,558 - 52,307,647 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,390,877 - 52,390,966 (-)NCBIHuRef
CHM1_1352,280,770 - 52,280,859 (-)NCBICHM1_1
T2T-CHM13v2.0352,327,118 - 52,327,207 (-)NCBIT2T-CHM13v2.0
Mir135a-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,031,323 - 106,031,412 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,031,323 - 106,031,412 (+)EnsemblGRCm39 Ensembl
GRCm389106,154,124 - 106,154,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,154,124 - 106,154,213 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,056,455 - 106,056,544 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera9105,778,138 - 105,778,227 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.46NCBI
MIR135A-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,461,817 - 37,461,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,461,817 - 37,461,903 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,443,376 - 37,443,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,811,966 - 37,812,052 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,811,966 - 37,812,052 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,175,890 - 37,175,976 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,584,560 - 37,584,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,869,243 - 37,869,329 (+)NCBIUU_Cfam_GSD_1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system nervous system renal system
High
Medium
Low 4 4 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000020047
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1334,441,079 - 34,441,168 (-)Ensembl
RefSeq Acc Id: NR_038482
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11334,441,079 - 34,441,168 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000018452 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000020047 ENTREZGENE
miRBase MI0002415 ENTREZGENE
NCBI Gene MIR135-1 ENTREZGENE
RNAcentral URS00000DF6D0 RNACentral
  URS000075A7B3 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR135-1  microRNA mir-135-1    microRNA 135-1  Symbol and/or name change 5135510 APPROVED