LOC100738909 (protein FAM228B) - Rat Genome Database

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Gene: LOC100738909 (protein FAM228B) Sus scrofa
Analyze
Symbol: LOC100738909 (Ensembl: FAM228B)
Name: protein FAM228B (Ensembl:family with sequence similarity 228 member B)
RGD ID: 14027253
Description: ENCODES a protein that exhibits isomerase activity (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (inferred); ASSOCIATED WITH essential tremor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); sarcoplasmic reticulum (inferred); sarcoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM228B; family with sequence similarity 228, member B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3114,537,226 - 114,577,956 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13114,537,223 - 114,577,993 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23121,802,237 - 121,842,918 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
LOC100738909
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3114,537,226 - 114,577,956 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13114,537,223 - 114,577,993 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23121,802,237 - 121,842,918 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAM228B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38224,076,833 - 24,169,638 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl224,076,526 - 24,169,640 (+)EnsemblGRCh38hg38GRCh38
GRCh37224,299,703 - 24,392,507 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36224,153,492 - 24,246,011 (+)NCBINCBI36Build 36hg18NCBI36
Celera224,186,680 - 24,232,794 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef224,085,236 - 24,131,349 (+)NCBIHuRef
CHM1_1224,275,739 - 24,321,882 (+)NCBICHM1_1
T2T-CHM13v2.0224,111,512 - 24,204,345 (+)NCBIT2T-CHM13v2.0
Fam228b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,789,888 - 4,819,259 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl124,789,888 - 4,819,267 (-)EnsemblGRCm39 Ensembl
GRCm38124,739,888 - 4,769,267 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl124,739,888 - 4,769,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv37124,753,022 - 4,776,073 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36124,759,902 - 4,786,253 (-)NCBIMGSCv36mm8
Celera124,677,842 - 4,701,107 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map122.09NCBI
Fam228b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8633,473,949 - 33,505,833 (-)NCBIGRCr8
mRatBN7.2627,754,505 - 27,786,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl627,754,506 - 27,786,537 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0630,037,995 - 30,070,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl630,038,777 - 30,053,581 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0639,817,106 - 39,849,116 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera627,223,967 - 27,256,367 (-)NCBICelera
Cytogenetic Map6q14NCBI
FAM228B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212102,349,894 - 102,437,493 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A102,353,857 - 102,441,457 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A24,074,642 - 24,166,411 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A24,217,534 - 24,263,434 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A24,218,442 - 24,261,486 (+)Ensemblpanpan1.1panPan2
FAM228B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11718,579,700 - 18,615,602 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1718,477,612 - 18,513,244 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01718,853,881 - 18,889,678 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1718,751,037 - 18,881,826 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11718,590,982 - 18,626,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01718,599,415 - 18,635,197 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01718,640,201 - 18,675,604 (+)NCBIUU_Cfam_GSD_1.0
LOC101962469
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629262,951,456 - 63,009,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364937,866,313 - 7,888,087 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364937,862,286 - 7,888,052 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM228B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11483,481,456 - 83,530,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1483,485,126 - 83,531,316 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604528,638,007 - 28,687,394 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam228b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247386,425,351 - 6,440,842 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247386,424,443 - 6,445,581 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC100738909
1837 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 15
Low 10 4 2 5 2 8 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000037752   ⟹   ENSSSCP00000037552
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3114,537,226 - 114,577,956 (-)Ensembl
RefSeq Acc Id: XM_021088366   ⟹   XP_020944025
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.13114,537,223 - 114,577,993 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088367   ⟹   XP_020944026
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.13114,537,223 - 114,577,972 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088368   ⟹   XP_020944027
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.13114,562,185 - 114,577,923 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020944025   ⟸   XM_021088366
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TWL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944026   ⟸   XM_021088367
- Peptide Label: isoform X2
- UniProtKB: A0A287A1F2 (UniProtKB/TrEMBL),   A0A4X1TZS8 (UniProtKB/TrEMBL),   A0A8D1E6B6 (UniProtKB/TrEMBL),   A0A8D1IM81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020944027   ⟸   XM_021088368
- Peptide Label: isoform X3
- UniProtKB: A0A8D1R057 (UniProtKB/TrEMBL),   A0A8D0W8B3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000037552   ⟸   ENSSSCT00000037752
Protein Domains
PPIase FKBP-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008584 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025048377 UniProtKB/TrEMBL
  ENSSSCG00030027716 UniProtKB/TrEMBL
  ENSSSCG00035058738 UniProtKB/TrEMBL
  ENSSSCG00040031619 UniProtKB/TrEMBL
  ENSSSCG00045026934 UniProtKB/TrEMBL
  ENSSSCG00050063455 UniProtKB/TrEMBL
  ENSSSCG00055019101 UniProtKB/TrEMBL
  ENSSSCG00060071286 UniProtKB/TrEMBL
  ENSSSCG00065006169 UniProtKB/TrEMBL
  ENSSSCG00070012915 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000037752 ENTREZGENE
  ENSSSCT00000037752.2 UniProtKB/TrEMBL
  ENSSSCT00025065791.1 UniProtKB/TrEMBL
  ENSSSCT00030038755.1 UniProtKB/TrEMBL
  ENSSSCT00035078622.1 UniProtKB/TrEMBL
  ENSSSCT00040042471.1 UniProtKB/TrEMBL
  ENSSSCT00045046005.1 UniProtKB/TrEMBL
  ENSSSCT00045046128.1 UniProtKB/TrEMBL
  ENSSSCT00050086429.1 UniProtKB/TrEMBL
  ENSSSCT00055037368.1 UniProtKB/TrEMBL
  ENSSSCT00060097712.1 UniProtKB/TrEMBL
  ENSSSCT00065008295.1 UniProtKB/TrEMBL
  ENSSSCT00070025218.1 UniProtKB/TrEMBL
  ENSSSCT00070025222.1 UniProtKB/TrEMBL
  ENSSSCT00070025228.1 UniProtKB/TrEMBL
  ENSSSCT00070025308.1 UniProtKB/TrEMBL
  ENSSSCT00070025311.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.50.40 UniProtKB/TrEMBL
InterPro FAM228 UniProtKB/TrEMBL
  PPIase_dom_sf UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/TrEMBL
NCBI Gene LOC100738909 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B UniProtKB/TrEMBL
  PROTEIN FAM228B UniProtKB/TrEMBL
  PTHR28584 UniProtKB/TrEMBL
Pfam FKBP_C UniProtKB/TrEMBL
PROSITE FKBP_PPIASE UniProtKB/TrEMBL
Superfamily-SCOP FKBP-like UniProtKB/TrEMBL
UniProt A0A287A1F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TUJ2_PIG UniProtKB/TrEMBL
  A0A4X1TWL2_PIG UniProtKB/TrEMBL
  A0A4X1TWL7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TZP3_PIG UniProtKB/TrEMBL
  A0A4X1TZS8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W8B3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1E6B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IM81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1R057 ENTREZGENE, UniProtKB/TrEMBL