GLI4 (GLI family zinc finger 4) - Rat Genome Database

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Gene: GLI4 (GLI family zinc finger 4) Sus scrofa
Analyze
Symbol: GLI4
Name: GLI family zinc finger 4
RGD ID: 14024922
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein 696; zinc finger protein GLI4; ZNF696
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,215,075 - 1,235,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,195,414 - 1,222,456 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,441,507 - 1,451,025 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GLI4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,215,075 - 1,235,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,195,414 - 1,222,456 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,441,507 - 1,451,025 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GLI4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,267,445 - 143,276,931 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,267,433 - 143,276,931 (+)EnsemblGRCh38hg38GRCh38
GRCh378144,349,615 - 144,359,101 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,420,982 - 144,430,476 (+)NCBINCBI36Build 36hg18NCBI36
Build 348144,420,981 - 144,430,474NCBI
Celera8140,658,886 - 140,668,338 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,603,232 - 139,612,752 (+)NCBIHuRef
CHM1_18144,389,851 - 144,399,309 (+)NCBICHM1_1
T2T-CHM13v2.08144,414,875 - 144,424,319 (+)NCBIT2T-CHM13v2.0
2810039B14Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,513,232 - 75,519,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,515,335 - 75,518,816 (+)EnsemblGRCm39 Ensembl
GRCm381575,645,021 - 75,647,437 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,642,129 - 75,653,643 (+)EnsemblGRCm38mm10GRCm38
MGSCv371575,473,916 - 75,477,866 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,450,171 - 75,477,866 (+)NCBIMGSCv36mm8
Celera1577,143,640 - 77,147,596 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.67NCBI
Gli4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,205,812 - 109,211,650 (+)NCBIGRCr8
mRatBN7.27107,325,584 - 107,330,911 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,325,607 - 107,330,907 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,060,537 - 109,065,754 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,284,207 - 111,289,424 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,230,128 - 111,235,345 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,671,931 - 116,677,188 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,671,948 - 116,677,901 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,565,871 - 116,571,122 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,579,245 - 113,584,458 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7103,688,535 - 103,693,753 (+)NCBICelera
Cytogenetic Map7q34NCBI
Gli4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554541,996,426 - 2,004,848 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554541,996,256 - 2,004,848 (+)NCBIChiLan1.0ChiLan1.0
GLI4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,729,451 - 160,754,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,247,003 - 136,272,512 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,999,582 - 140,025,091 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,036,974 - 143,045,866 (+)NCBIpanpan1.1PanPan1.1panPan2
GLI4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,029,553 - 37,035,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,028,512 - 37,035,454 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,982,079 - 36,988,003 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,500,865 - 37,526,485 (+)NCBIROS_Cfam_1.0
UU_Cfam_GSD_1.01337,769,200 - 37,775,129 (+)NCBIUU_Cfam_GSD_1.0
Gli4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,338,960 - 1,346,546 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,767,408 - 8,772,529 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,767,797 - 8,772,590 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLI4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,477,338 - 137,501,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,491,467 - 137,498,821 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,410,832 - 2,462,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gli4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473513,455,746 - 13,464,627 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473513,459,082 - 13,469,288 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GLI4
871 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000043705   ⟹   ENSSSCP00000056279
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,212,546 - 1,222,032 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000068646   ⟹   ENSSSCP00000070966
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,215,075 - 1,221,442 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078098   ⟹   ENSSSCP00000066783
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,215,076 - 1,221,578 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000084837   ⟹   ENSSSCP00000071208
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,215,066 - 1,221,457 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000097418   ⟹   ENSSSCP00000080993
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,216,836 - 1,235,163 (-)Ensembl
RefSeq Acc Id: XM_021090359   ⟹   XP_020946018
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.141,195,414 - 1,222,456 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020946018 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000066783.2
  ENSSSCP00000070966.2
  ENSSSCP00000080993.1
  ENSSSCP00005016765.1
Reference Protein Sequences
RefSeq Acc Id: XP_020946018   ⟸   XM_021090359
- Sequence:
RefSeq Acc Id: ENSSSCP00000070966   ⟸   ENSSSCT00000068646
RefSeq Acc Id: ENSSSCP00000066783   ⟸   ENSSSCT00000078098
RefSeq Acc Id: ENSSSCP00000071208   ⟸   ENSSSCT00000084837
RefSeq Acc Id: ENSSSCP00000056279   ⟸   ENSSSCT00000043705
RefSeq Acc Id: ENSSSCP00000080993   ⟸   ENSSSCT00000097418
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039881 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005017445 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000068646.2 UniProtKB/TrEMBL
  ENSSSCT00000078098.2 UniProtKB/TrEMBL
  ENSSSCT00000097418.1 UniProtKB/TrEMBL
  ENSSSCT00005027534.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene GLI4 ENTREZGENE
PANTHER ZINC FINGER PROTEIN 728-LIKE UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZIC AND GLI UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A480J3Q7_PIG UniProtKB/TrEMBL
  A0A5G2QPF7_PIG UniProtKB/TrEMBL
  A0A8D0IUY1_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2R1B4 UniProtKB/TrEMBL
  A0A8W4FP81 UniProtKB/TrEMBL