TRMT1L (tRNA methyltransferase 1 like) - Rat Genome Database

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Gene: TRMT1L (tRNA methyltransferase 1 like) Sus scrofa
Analyze
Symbol: TRMT1L
Name: tRNA methyltransferase 1 like
RGD ID: 14024343
Description: ENCODES a protein that exhibits metal ion binding (inferred); methyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN adult behavior (ortholog); adult locomotory behavior (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); megacolon (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TRMT1-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9126,300,390 - 126,347,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19126,302,642 - 126,347,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29138,748,234 - 138,795,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRMT1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9126,300,390 - 126,347,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19126,302,642 - 126,347,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29138,748,234 - 138,795,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,118,101 - 185,157,537 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,118,101 - 185,157,072 (-)EnsemblGRCh38hg38GRCh38
GRCh371185,087,233 - 185,126,230 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361183,353,856 - 183,392,706 (-)NCBINCBI36Build 36hg18NCBI36
Build 341181,818,893 - 181,857,740NCBI
Celera1158,197,913 - 158,236,811 (-)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1156,322,500 - 156,361,523 (-)NCBIHuRef
CHM1_11186,508,906 - 186,547,935 (-)NCBICHM1_1
T2T-CHM13v2.01184,475,011 - 184,514,447 (-)NCBIT2T-CHM13v2.0
Trmt1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,304,293 - 151,333,934 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,304,293 - 151,333,912 (+)EnsemblGRCm39 Ensembl
GRCm381151,428,542 - 151,458,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,428,542 - 151,458,161 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,275,778 - 153,305,313 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,190,866 - 153,220,377 (+)NCBIMGSCv36mm8
Celera1153,857,643 - 153,887,243 (+)NCBICelera
Cytogenetic Map1G1NCBI
cM Map164.12NCBI
Trmt1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,060,186 - 66,093,247 (+)NCBIGRCr8
mRatBN7.21363,510,097 - 63,543,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,510,204 - 63,543,266 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1366,129,826 - 66,162,884 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,394,444 - 67,427,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,657,528 - 64,690,880 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,785,889 - 68,819,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,785,827 - 68,818,990 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01373,748,125 - 73,781,250 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41366,301,000 - 66,334,062 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11366,314,936 - 66,347,916 (+)NCBI
Celera1363,441,064 - 63,474,125 (+)NCBICelera
Cytogenetic Map13q21NCBI
Trmt1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540623,735,715 - 23,772,010 (-)NCBIChiLan1.0ChiLan1.0
TRMT1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2164,565,241 - 64,604,765 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,248,811 - 64,288,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,642,659 - 160,681,709 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,795,113 - 164,833,940 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,795,113 - 164,833,940 (-)Ensemblpanpan1.1panPan2
TRMT1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1718,294,489 - 18,330,002 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl718,295,027 - 18,329,730 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha717,878,671 - 17,914,734 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0718,026,950 - 18,063,131 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl718,026,953 - 18,062,433 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1717,936,505 - 17,971,963 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0718,044,297 - 18,080,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0718,175,449 - 18,211,438 (-)NCBIUU_Cfam_GSD_1.0
Trmt1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934487,177,383 - 87,205,051 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364815,023,826 - 5,054,734 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364815,024,218 - 5,051,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12544,232,374 - 44,272,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2544,232,433 - 44,272,616 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605545,438,628 - 45,478,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trmt1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248148,409,949 - 8,434,833 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRMT1L
1427 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 3 3 5 2 23 2 3 3
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000029214   ⟹   ENSSSCP00000023028
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9126,300,390 - 126,347,256 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000049159   ⟹   ENSSSCP00000033757
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9126,302,653 - 126,347,274 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091286   ⟹   ENSSSCP00000065128
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9126,303,525 - 126,347,273 (-)Ensembl
RefSeq Acc Id: XM_021102636   ⟹   XP_020958295
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19126,302,642 - 126,347,276 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002347095
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19126,302,644 - 126,347,277 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020958295 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000023028
  ENSSSCP00000023028.3
  ENSSSCP00000033757.2
  ENSSSCP00000065128.2
  ENSSSCP00005030204.1
  ENSSSCP00065002415.1
RefSeq Acc Id: XP_020958295   ⟸   XM_021102636
- UniProtKB: A0A8D1XAV8 (UniProtKB/TrEMBL),   A0A8D0JUX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000033757   ⟸   ENSSSCT00000049159
RefSeq Acc Id: ENSSSCP00000023028   ⟸   ENSSSCT00000029214
RefSeq Acc Id: ENSSSCP00000065128   ⟸   ENSSSCT00000091286
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021393 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005030554 UniProtKB/TrEMBL
  ENSSSCG00065003954 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000029214 ENTREZGENE
  ENSSSCT00000029214.4 UniProtKB/TrEMBL
  ENSSSCT00000049159.3 UniProtKB/TrEMBL
  ENSSSCT00000091286.2 UniProtKB/TrEMBL
  ENSSSCT00005048940.1 UniProtKB/TrEMBL
  ENSSSCT00065005449.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.56.70 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro SAM-dependent_MTases UniProtKB/TrEMBL
  Trm1 UniProtKB/TrEMBL
  tRNA_met_Trm1_C UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene TRMT1L ENTREZGENE
PANTHER PTHR10631 UniProtKB/TrEMBL
  TRMT1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam TRM UniProtKB/TrEMBL
PROSITE SAM_MT_TRM1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A286ZQK8_PIG UniProtKB/TrEMBL
  A0A5G2QKR8_PIG UniProtKB/TrEMBL
  A0A8D0JUX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1XAV8 ENTREZGENE, UniProtKB/TrEMBL
  I3LG35_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94447 ENTREZGENE