CCDC146 (coiled-coil domain containing 146) - Rat Genome Database

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Gene: CCDC146 (coiled-coil domain containing 146) Sus scrofa
Analyze
Symbol: CCDC146
Name: coiled-coil domain containing 146
RGD ID: 14022642
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN cell morphogenesis (ortholog); flagellated sperm motility (ortholog); gene expression (ortholog); ASSOCIATED WITH Chromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MB (ortholog); genetic disease (ortholog); male infertility (ortholog); FOUND IN centriole (inferred); centrosome (inferred); cytoskeleton (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil domain-containing protein 146
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9102,787,551 - 102,919,686 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19102,784,299 - 102,919,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,119,508 - 113,148,339 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCDC146
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9102,787,551 - 102,919,686 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19102,784,299 - 102,919,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,119,508 - 113,148,339 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC146
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38777,122,615 - 77,295,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl777,122,434 - 77,329,533 (+)EnsemblGRCh38hg38GRCh38
GRCh37776,751,932 - 76,924,521 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36776,589,870 - 76,762,457 (+)NCBINCBI36Build 36hg18NCBI36
Celera771,497,691 - 71,625,151 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef771,399,435 - 71,526,851 (+)NCBIHuRef
CHM1_1776,682,189 - 76,854,481 (+)NCBICHM1_1
T2T-CHM13v2.0778,373,727 - 78,546,266 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2776,084,997 - 76,257,584 (+)NCBI
Ccdc146
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,496,749 - 21,629,675 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,497,959 - 21,629,675 (-)EnsemblGRCm39 Ensembl
GRCm38521,292,422 - 21,424,677 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl521,292,961 - 21,424,677 (-)EnsemblGRCm38mm10GRCm38
MGSCv37520,798,779 - 20,930,495 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36520,331,135 - 20,400,919 (-)NCBIMGSCv36mm8
Celera518,256,333 - 18,388,433 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.83NCBI
Ccdc146
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,554,966 - 14,703,801 (+)NCBIGRCr8
mRatBN7.2413,662,766 - 13,811,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,662,766 - 13,811,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,790,248 - 18,942,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,599,535 - 14,744,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,975,890 - 13,127,983 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0410,269,798 - 10,421,724 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,295,122 - 10,421,415 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,265,819 - 10,414,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,233,108 - 9,304,850 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera49,228,536 - 9,375,127 (+)NCBICelera
Cytogenetic Map4q11NCBI
Ccdc146
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554107,811,034 - 7,961,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554107,810,702 - 7,925,844 (-)NCBIChiLan1.0ChiLan1.0
CCDC146
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2694,973,816 - 95,145,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17143,160,317 - 143,410,611 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0768,965,404 - 69,215,833 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1782,900,402 - 83,027,578 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl782,900,402 - 83,027,578 (+)Ensemblpanpan1.1panPan2
CCDC146
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11817,286,319 - 17,405,120 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1817,304,941 - 17,404,914 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1816,944,929 - 17,063,563 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,605,995 - 17,725,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,625,038 - 17,725,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11817,357,017 - 17,475,799 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01817,295,954 - 17,414,787 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,565,170 - 17,684,371 (+)NCBIUU_Cfam_GSD_1.0
Ccdc146
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,449,069 - 59,580,733 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,572,865 - 20,704,511 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,572,865 - 20,703,791 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC146
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12171,634,139 - 71,807,739 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2171,634,069 - 71,807,442 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604232,189,617 - 32,367,298 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc146
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473926,474,281 - 26,581,666 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473926,445,872 - 26,580,775 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC146
3565 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 1 23 1 3 3
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016787   ⟹   ENSSSCP00000016339
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9102,787,551 - 102,919,686 (-)Ensembl
RefSeq Acc Id: XM_021102558   ⟹   XP_020958217
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19102,784,299 - 102,919,758 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020958217 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000016339
  ENSSSCP00000016339.4
  ENSSSCP00040023479.1
  ENSSSCP00050003845.1
  ENSSSCP00060040114.1
  ENSSSCP00070038929.1
Reference Protein Sequences
RefSeq Acc Id: XP_020958217   ⟸   XM_021102558
- UniProtKB: A0A4X1VB77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016339   ⟸   ENSSSCT00000016787


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015412 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040042165 UniProtKB/TrEMBL
  ENSSSCG00050006610 UniProtKB/TrEMBL
  ENSSSCG00060068001 UniProtKB/TrEMBL
  ENSSSCG00070023159 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016787 ENTREZGENE
  ENSSSCT00000016787.5 UniProtKB/TrEMBL
  ENSSSCT00040056416.1 UniProtKB/TrEMBL
  ENSSSCT00050009023.1 UniProtKB/TrEMBL
  ENSSSCT00060092806.1 UniProtKB/TrEMBL
  ENSSSCT00070046152.1 UniProtKB/TrEMBL
NCBI Gene CCDC146 ENTREZGENE
PANTHER CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED UniProtKB/TrEMBL
  COILED-COIL DOMAIN-CONTAINING PROTEIN 146 UniProtKB/TrEMBL
UniProt A0A4X1VB77 ENTREZGENE, UniProtKB/TrEMBL
  F1SB85_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86261 ENTREZGENE