LOC110257188 (beta-defensin 15-like) - Rat Genome Database

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Gene: LOC110257188 (beta-defensin 15-like) Sus scrofa
Analyze
Symbol: LOC110257188
Name: beta-defensin 15-like
RGD ID: 14022636
Description: ENCODES a protein that exhibits CCR2 chemokine receptor binding (ortholog); heparin binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN defense response to bacterium (inferred); innate immune response (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (ortholog); microvesicle (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11537,989,086 - 37,996,091 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC110257188
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11537,989,086 - 37,996,091 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DEFB106B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3887,482,504 - 7,486,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl87,482,504 - 7,486,400 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl87,825,139 - 7,829,053 (+)EnsemblGRCh38hg38GRCh38
GRCh3787,340,026 - 7,343,922 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3687,327,436 - 7,331,319 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map8p23.1NCBI
HuRef86,965,939 - 6,967,992 (+)NCBIHuRef
CHM1_187,283,884 - 7,287,767 (+)NCBICHM1_1
T2T-CHM13v2.087,211,498 - 7,215,418 (-)NCBIT2T-CHM13v2.0
Defb15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39822,419,813 - 22,422,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl822,419,815 - 22,422,726 (-)EnsemblGRCm39 Ensembl
GRCm38821,929,813 - 21,932,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl821,929,799 - 21,932,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv37823,040,285 - 23,043,182 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36823,395,344 - 23,398,256 (-)NCBIMGSCv36mm8
Celera823,420,631 - 23,423,529 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map810.64NCBI
Defb15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81676,843,661 - 76,846,359 (+)NCBIGRCr8
mRatBN7.21670,141,193 - 70,143,891 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1670,141,193 - 70,143,834 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1675,414,882 - 75,417,523 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01679,459,938 - 79,462,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01674,709,360 - 74,712,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01675,105,290 - 75,107,931 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,105,290 - 75,107,931 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,122,996 - 75,125,627 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01674,663,812 - 74,666,453 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41674,818,206 - 74,820,847 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1668,585,304 - 68,587,938 (-)NCBICelera
Cytogenetic Map16q12.5NCBI

Variants

.
Variants in LOC110257188
193 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 7 4 3 4 2 20 1 1 1
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021076393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021076393   ⟹   XP_020932052
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11537,989,086 - 37,996,091 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020932052   ⟸   XM_021076393
- UniProtKB: A0A8W4FH76 (UniProtKB/TrEMBL),   A0A4X1VY46 (UniProtKB/TrEMBL),   A0A8D0WXF0 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Beta-defensin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000055607 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005023603 UniProtKB/TrEMBL
  ENSSSCG00025002099 UniProtKB/TrEMBL
  ENSSSCG00030041781 UniProtKB/TrEMBL
  ENSSSCG00035028279 UniProtKB/TrEMBL
  ENSSSCG00040063763 UniProtKB/TrEMBL
  ENSSSCG00045005237 UniProtKB/TrEMBL
  ENSSSCG00050021153 UniProtKB/TrEMBL
  ENSSSCG00055000882 UniProtKB/TrEMBL
  ENSSSCG00065048509 UniProtKB/TrEMBL
  ENSSSCG00070027375 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000105137 ENTREZGENE
  ENSSSCT00000105137.1 UniProtKB/TrEMBL
  ENSSSCT00005037333.1 UniProtKB/TrEMBL
  ENSSSCT00025002681.1 UniProtKB/TrEMBL
  ENSSSCT00030058108.1 UniProtKB/TrEMBL
  ENSSSCT00035037396.1 UniProtKB/TrEMBL
  ENSSSCT00040087048.1 UniProtKB/TrEMBL
  ENSSSCT00045008696.1 UniProtKB/TrEMBL
  ENSSSCT00050028510.1 UniProtKB/TrEMBL
  ENSSSCT00055001553.1 UniProtKB/TrEMBL
  ENSSSCT00065066358.1 UniProtKB/TrEMBL
  ENSSSCT00070054909.1 UniProtKB/TrEMBL
InterPro Beta_defensin UniProtKB/TrEMBL
NCBI Gene LOC110257188 ENTREZGENE
Pfam Defensin_beta_2 UniProtKB/TrEMBL
UniProt A0A4X1VY46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WXF0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FH76 ENTREZGENE, UniProtKB/TrEMBL