CHP2 (calcineurin like EF-hand protein 2) - Rat Genome Database

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Gene: CHP2 (calcineurin like EF-hand protein 2) Sus scrofa
Analyze
Symbol: CHP2
Name: calcineurin like EF-hand protein 2
RGD ID: 14020433
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to calcium ion (inferred); positive regulation of calcineurin-NFAT signaling cascade (inferred); positive regulation of cell population proliferation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred); INTERACTS WITH zearalenone
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcineurin B homologous protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl322,473,247 - 22,478,588 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1322,473,241 - 22,478,697 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
CHP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl322,473,247 - 22,478,588 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1322,473,241 - 22,478,697 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CHP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381623,755,026 - 23,758,935 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1623,755,026 - 23,758,935 (+)EnsemblGRCh38hg38GRCh38
GRCh371623,766,347 - 23,770,256 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361623,673,449 - 23,677,757 (+)NCBINCBI36Build 36hg18NCBI36
Celera1622,544,109 - 22,548,418 (+)NCBICelera
Cytogenetic Map16p12.2NCBI
HuRef1621,855,543 - 21,859,868 (+)NCBIHuRef
CHM1_11624,776,237 - 24,780,562 (+)NCBICHM1_1
T2T-CHM13v2.01624,028,856 - 24,032,766 (+)NCBIT2T-CHM13v2.0
Chp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397121,807,839 - 121,823,094 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7121,818,719 - 121,822,047 (+)EnsemblGRCm39 Ensembl
GRCm387122,208,621 - 122,222,539 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7122,219,496 - 122,222,824 (+)EnsemblGRCm38mm10GRCm38
MGSCv377129,363,010 - 129,366,053 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367122,010,628 - 122,014,157 (+)NCBIMGSCv36mm8
Celera7122,109,863 - 122,112,971 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map765.62NCBI
Chp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81186,189,090 - 186,203,663 (+)NCBIGRCr8
mRatBN7.21176,757,945 - 176,772,443 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1176,757,876 - 176,772,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1185,096,765 - 185,099,920 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01192,282,733 - 192,285,888 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,966,885 - 184,970,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01192,169,634 - 192,173,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1192,169,841 - 192,173,253 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01199,230,968 - 199,234,018 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,055,296 - 181,058,207 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11181,195,210 - 181,198,123 (+)NCBI
Celera1174,477,349 - 174,480,508 (+)NCBICelera
Cytogenetic Map1q36NCBI
Chp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554932,275,892 - 2,281,178 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554932,278,494 - 2,281,125 (+)NCBIChiLan1.0ChiLan1.0
CHP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21825,163,763 - 25,169,054 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11629,683,249 - 29,688,520 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01614,354,139 - 14,358,463 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11624,002,908 - 24,007,232 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1624,002,908 - 24,007,232 (+)Ensemblpanpan1.1panPan2
CHP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1622,127,422 - 22,129,637 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha623,692,416 - 23,695,700 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0622,268,938 - 22,272,231 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl622,268,470 - 22,272,191 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1622,073,288 - 22,076,560 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0621,975,160 - 21,978,449 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0622,370,651 - 22,373,928 (-)NCBIUU_Cfam_GSD_1.0
Chp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344120,276,462 - 120,279,355 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365018,374,323 - 8,377,155 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365018,374,323 - 8,377,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1521,471,384 - 21,476,454 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl521,472,349 - 21,476,611 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660688,320,103 - 8,324,406 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247828,873,085 - 8,876,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247828,873,003 - 8,881,370 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHP2
100 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 4
Low 2 1 2 2 1
Below cutoff 2 1 13 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000062165   ⟹   ENSSSCP00000044450
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl322,473,247 - 22,478,588 (-)Ensembl
RefSeq Acc Id: XM_021086461   ⟹   XP_020942120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1322,473,241 - 22,478,697 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020942120   ⟸   XM_021086461
- UniProtKB: A0A287AKN3 (UniProtKB/TrEMBL),   A0A4X1UYK2 (UniProtKB/TrEMBL),   A0A8D0IJ26 (UniProtKB/TrEMBL),   A0A8D1KHX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000044450   ⟸   ENSSSCT00000062165
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034827 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005010332 UniProtKB/TrEMBL
  ENSSSCG00015030362 UniProtKB/TrEMBL
  ENSSSCG00025045259 UniProtKB/TrEMBL
  ENSSSCG00030066020 UniProtKB/TrEMBL
  ENSSSCG00035022433 UniProtKB/TrEMBL
  ENSSSCG00040061918 UniProtKB/TrEMBL
  ENSSSCG00045037782 UniProtKB/TrEMBL
  ENSSSCG00050078385 UniProtKB/TrEMBL
  ENSSSCG00055008824 UniProtKB/TrEMBL
  ENSSSCG00060022032 UniProtKB/TrEMBL
  ENSSSCG00065038349 UniProtKB/TrEMBL
  ENSSSCG00070020317 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000062165 ENTREZGENE
  ENSSSCT00000062165.2 UniProtKB/TrEMBL
  ENSSSCT00005015989.1 UniProtKB/TrEMBL
  ENSSSCT00015040319.1 UniProtKB/TrEMBL
  ENSSSCT00025061597.1 UniProtKB/TrEMBL
  ENSSSCT00030092230.1 UniProtKB/TrEMBL
  ENSSSCT00030092262.1 UniProtKB/TrEMBL
  ENSSSCT00035029277.1 UniProtKB/TrEMBL
  ENSSSCT00035029283.1 UniProtKB/TrEMBL
  ENSSSCT00040084271.1 UniProtKB/TrEMBL
  ENSSSCT00040084324.1 UniProtKB/TrEMBL
  ENSSSCT00040084382.1 UniProtKB/TrEMBL
  ENSSSCT00045065281.1 UniProtKB/TrEMBL
  ENSSSCT00045065305.1 UniProtKB/TrEMBL
  ENSSSCT00050107986.1 UniProtKB/TrEMBL
  ENSSSCT00055017220.1 UniProtKB/TrEMBL
  ENSSSCT00055017264.1 UniProtKB/TrEMBL
  ENSSSCT00060029893.1 UniProtKB/TrEMBL
  ENSSSCT00065052421.1 UniProtKB/TrEMBL
  ENSSSCT00070040321.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene CHP2 ENTREZGENE
PANTHER CALCINEURIN B HOMOLOGOUS PROTEIN 2 UniProtKB/TrEMBL
  EG:114D9.1 PROTEIN-RELATED UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A287AKN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UYK2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IJ26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z1K6_PIG UniProtKB/TrEMBL
  A0A8D1FDV9_PIG UniProtKB/TrEMBL
  A0A8D1FMF4_PIG UniProtKB/TrEMBL
  A0A8D1JI05_PIG UniProtKB/TrEMBL
  A0A8D1KHX3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1TYK0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86658 ENTREZGENE