LAMB3 (laminin subunit beta 3) - Rat Genome Database

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Gene: LAMB3 (laminin subunit beta 3) Sus scrofa
Analyze
Symbol: LAMB3
Name: laminin subunit beta 3
RGD ID: 14020222
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1A (ortholog); autistic disorder (ortholog); FOUND IN basement membrane (inferred); laminin complex (inferred); laminin-5 complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: laminin subunit beta-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,311,834 - 133,351,197 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,298,009 - 133,351,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,594,591 - 146,598,263 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LAMB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,311,834 - 133,351,197 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,298,009 - 133,351,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,594,591 - 146,598,263 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381209,614,870 - 209,652,425 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1209,614,870 - 209,652,425 (-)EnsemblGRCh38hg38GRCh38
GRCh371209,788,215 - 209,825,770 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361207,854,838 - 207,892,443 (-)NCBINCBI36Build 36hg18NCBI36
Build 341206,176,639 - 206,214,152NCBI
Celera1183,019,124 - 183,056,711 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1180,463,503 - 180,501,095 (-)NCBIHuRef
CHM1_11211,060,621 - 211,098,219 (-)NCBICHM1_1
T2T-CHM13v2.01208,861,637 - 208,900,810 (-)NCBIT2T-CHM13v2.0
Lamb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,976,661 - 193,026,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,890,007 - 193,026,186 (+)EnsemblGRCm39 Ensembl
GRCm381193,294,353 - 193,343,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,207,699 - 193,343,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv371195,128,188 - 195,170,072 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361195,002,753 - 195,044,602 (+)NCBIMGSCv36mm8
Celera1200,179,164 - 200,221,182 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.71NCBI
Lamb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,362,514 - 107,404,081 (+)NCBIGRCr8
mRatBN7.213104,833,810 - 104,875,405 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,833,873 - 104,875,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,351,461 - 107,392,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,735,317 - 108,776,855 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,953,273 - 105,994,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013112,031,614 - 112,073,187 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13112,031,594 - 112,073,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,587,097 - 116,628,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,148,815 - 109,190,322 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13104,263,258 - 104,304,743 (+)NCBICelera
Cytogenetic Map13q27NCBI
Lamb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554892,568,650 - 2,607,595 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554892,547,611 - 2,603,079 (+)NCBIChiLan1.0ChiLan1.0
LAMB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,740,768 - 39,786,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,708,426 - 39,752,535 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,191,401 - 185,245,154 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11189,996,634 - 190,034,206 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1189,996,639 - 190,034,206 (-)Ensemblpanpan1.1panPan2
LAMB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,272,326 - 8,313,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,272,736 - 8,310,474 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha77,849,692 - 7,976,332 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.077,973,087 - 8,099,489 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl77,973,113 - 8,012,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.177,902,916 - 8,029,231 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,000,050 - 8,126,276 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,060,953 - 8,187,735 (-)NCBIUU_Cfam_GSD_1.0
Lamb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934466,190,090 - 66,247,713 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365573,450,247 - 3,487,954 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365573,429,488 - 3,487,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,805,234 - 19,856,025 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,807,045 - 19,846,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605520,402,855 - 20,458,028 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248072,320,168 - 2,378,349 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LAMB3
2636 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 8 2 3 5 1 21 3 1
Below cutoff 1 1 1 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017012   ⟹   ENSSSCP00000016558
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9133,311,834 - 133,351,197 (+)Ensembl
RefSeq Acc Id: XM_021063882   ⟹   XP_020919541
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19133,298,009 - 133,351,162 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020919541   ⟸   XM_021063882
- UniProtKB: F1SF45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016558   ⟸   ENSSSCT00000017012
Protein Domains
Laminin EGF-like   Laminin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00055000715 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017012 ENTREZGENE
  ENSSSCT00000017012.4 UniProtKB/TrEMBL
  ENSSSCT00055001418.1 UniProtKB/TrEMBL
  ENSSSCT00055001481.1 UniProtKB/TrEMBL
  ENSSSCT00055001511.1 UniProtKB/TrEMBL
  ENSSSCT00055001538.1 UniProtKB/TrEMBL
  ENSSSCT00055001627.1 UniProtKB/TrEMBL
  ENSSSCT00055001658.1 UniProtKB/TrEMBL
  ENSSSCT00055001678.1 UniProtKB/TrEMBL
Gene3D-CATH Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
NCBI Gene LAMB3 ENTREZGENE
PANTHER LAMININ SUBUNIT BETA-3 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
Pfam Laminin_EGF UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt A0A8D1P5G4_PIG UniProtKB/TrEMBL
  A0A8D1PBN9_PIG UniProtKB/TrEMBL
  F1SF45 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89622 ENTREZGENE