LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) - Rat Genome Database

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Gene: LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) Sus scrofa
Analyze
Symbol: LAMTOR1
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
RGD ID: 14015948
Description: ENCODES a protein that exhibits GTPase binding (inferred); guanyl-nucleotide exchange factor activity (inferred); molecular adaptor activity (inferred); INVOLVED IN cellular protein localization (inferred); cellular response to amino acid stimulus (inferred); cholesterol homeostasis (inferred); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); intellectual disability (ortholog); FOUND IN late endosome membrane (ortholog); lysosome (ortholog); membrane raft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ragulator complex protein LAMTOR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,672,475 - 6,680,053 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,674,045 - 6,680,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,435,536 - 7,441,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:15679890  


Genomics

Comparative Map Data
LAMTOR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,672,475 - 6,680,053 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,674,045 - 6,680,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,435,536 - 7,441,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMTOR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1172,085,895 - 72,103,297 (-)EnsemblGRCh38hg38GRCh38
GRCh381172,097,292 - 72,103,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371171,808,338 - 71,814,343 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,485,986 - 71,491,970 (-)NCBINCBI36hg18NCBI36
Celera1169,110,285 - 69,116,380 (-)NCBI
Cytogenetic Map11q13.4NCBI
HuRef1168,101,932 - 68,108,027 (-)NCBIHuRef
CHM1_11171,692,146 - 71,698,241 (-)NCBICHM1_1
Lamtor1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,555,044 - 101,561,110 (+)NCBIGRCm39mm39
GRCm39 Ensembl7101,555,111 - 101,575,882 (+)Ensembl
GRCm387101,905,837 - 101,911,903 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,905,904 - 101,926,675 (+)EnsemblGRCm38mm10GRCm38
MGSCv377109,054,351 - 109,060,417 (+)NCBIGRCm37mm9NCBIm37
MGSCv367101,779,750 - 101,785,705 (+)NCBImm8
Celera7102,280,164 - 102,286,229 (+)NCBICelera
Cytogenetic Map7E2NCBI
Lamtor1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,272,116 - 156,277,687 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1156,272,064 - 156,291,179 (+)Ensembl
Rnor_6.01166,991,474 - 166,997,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,991,474 - 166,997,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,182,228 - 173,187,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,367,471 - 159,373,042 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11159,446,487 - 159,452,059 (+)NCBI
Celera1154,345,774 - 154,351,345 (+)NCBICelera
Cytogenetic Map1q32NCBI
Lamtor1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,228,615 - 19,247,765 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,228,615 - 19,235,523 (+)NCBIChiLan1.0ChiLan1.0
LAMTOR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11170,401,167 - 70,407,246 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,390,141 - 70,407,246 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01167,177,580 - 67,183,631 (-)NCBIMhudiblu_PPA_v0panPan3
LAMTOR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,981,170 - 25,986,942 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2125,981,254 - 25,996,432 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,750,825 - 25,756,606 (+)NCBI
ROS_Cfam_1.02126,190,008 - 26,195,789 (+)NCBI
UMICH_Zoey_3.12125,981,266 - 25,987,047 (+)NCBI
UNSW_CanFamBas_1.02126,197,390 - 26,203,172 (+)NCBI
UU_Cfam_GSD_1.02126,099,021 - 26,104,803 (+)NCBI
Lamtor1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,847,252 - 59,860,045 (-)NCBI
SpeTri2.0NW_0049364981,446,794 - 1,459,590 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMTOR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,301,354 - 63,307,716 (-)NCBI
ChlSab1.1 Ensembl163,301,885 - 63,307,553 (-)Ensembl
Vero_WHO_p1.0NW_02366604362,591,235 - 62,597,696 (+)NCBI
Lamtor1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248174,872,630 - 4,879,217 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 2 2 5 2 2 2
Low 9 4 3 3 18 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016155   ⟹   ENSSSCP00000015723
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl96,674,049 - 6,680,018 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000066885   ⟹   ENSSSCP00000061672
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl96,672,475 - 6,680,053 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000081655   ⟹   ENSSSCP00000073191
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl96,674,048 - 6,679,945 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000084400   ⟹   ENSSSCP00000074004
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl96,674,896 - 6,680,053 (-)Ensembl
RefSeq Acc Id: XM_003129591   ⟹   XP_003129639
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.196,674,045 - 6,680,067 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003129639 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003129639   ⟸   XM_003129591
- UniProtKB: F2Z5W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015723   ⟸   ENSSSCT00000016155
RefSeq Acc Id: ENSSSCP00000074004   ⟸   ENSSSCT00000084400
RefSeq Acc Id: ENSSSCP00000061672   ⟸   ENSSSCT00000066885
RefSeq Acc Id: ENSSSCP00000073191   ⟸   ENSSSCT00000081655


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014804 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070021178 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000015723 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000061672 UniProtKB/TrEMBL
  ENSSSCP00000073191 UniProtKB/TrEMBL
  ENSSSCP00000074004 UniProtKB/TrEMBL
  ENSSSCP00070035355 UniProtKB/TrEMBL
  ENSSSCP00070035360 UniProtKB/TrEMBL
  ENSSSCP00070035363 UniProtKB/TrEMBL
  ENSSSCP00070035370 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016155 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000066885 UniProtKB/TrEMBL
  ENSSSCT00000081655 UniProtKB/TrEMBL
  ENSSSCT00000084400 UniProtKB/TrEMBL
  ENSSSCT00070042079 UniProtKB/TrEMBL
  ENSSSCT00070042083 UniProtKB/TrEMBL
  ENSSSCT00070042086 UniProtKB/TrEMBL
  ENSSSCT00070042093 UniProtKB/TrEMBL
InterPro LAMTOR1/MEH1 UniProtKB/TrEMBL
KEGG Report ssc:100520503 UniProtKB/TrEMBL
NCBI Gene LAMTOR1 ENTREZGENE
Pfam LAMTOR UniProtKB/TrEMBL
SMART LAMTOR UniProtKB/TrEMBL
UniProt A0A4X1UYG1_PIG UniProtKB/TrEMBL
  A0A4X1UYG7_PIG UniProtKB/TrEMBL
  A0A4X1V252_PIG UniProtKB/TrEMBL
  A0A4X1V3R0_PIG UniProtKB/TrEMBL
  A0A5G2QB49_PIG UniProtKB/TrEMBL
  A0A5G2R9M7_PIG UniProtKB/TrEMBL
  A0A5G2RET7_PIG UniProtKB/TrEMBL
  F2Z5W6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89629 ENTREZGENE