LARGE1 (LARGE xylosyl- and glucuronyltransferase 1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: LARGE1 (LARGE xylosyl- and glucuronyltransferase 1) Sus scrofa
Analyze
Symbol: LARGE1
Name: LARGE xylosyl- and glucuronyltransferase 1
RGD ID: 14015179
Description: ENCODES a protein that exhibits glucuronosyltransferase activity (ortholog); transferase activity, transferring glycosyl groups (ortholog); xylosyltransferase activity (ortholog); INVOLVED IN muscle cell cellular homeostasis (ortholog); protein O-linked mannosylation (ortholog); skeletal muscle organ development (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); congenital muscular dystrophy (ortholog); congenital muscular dystrophy-dystroglycanopathy type A6 (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: glycosyltransferase-like protein LARGE1; n-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.25110,211,538 - 110,349,654 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
LARGE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.25110,211,538 - 110,349,654 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LARGE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2233,162,226 - 33,922,841 (-)EnsemblGRCh38hg38GRCh38
GRCh382233,162,237 - 33,922,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372233,668,495 - 34,318,812 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,999,063 - 32,646,410 (-)NCBINCBI36hg18NCBI36
Build 342231,993,616 - 32,640,964NCBI
Celera2217,471,158 - 18,118,297 (-)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2216,626,665 - 17,273,268 (-)NCBIHuRef
CHM1_12233,628,484 - 34,276,127 (-)NCBICHM1_1
Large1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39873,541,226 - 74,080,279 (-)NCBIGRCm39mm39
GRCm39 Ensembl873,541,227 - 74,080,168 (-)Ensembl
GRCm38872,814,598 - 73,353,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,814,599 - 73,353,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv37875,338,498 - 75,876,455 (-)NCBIGRCm37mm9NCBIm37
MGSCv36875,710,671 - 76,248,628 (-)NCBImm8
Celera877,131,292 - 77,664,765 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map835.08NCBI
Large1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21911,603,129 - 12,048,930 (-)NCBI
Rnor_6.0 Ensembl1912,481,540 - 12,942,963 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01912,481,563 - 12,945,320 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01923,595,328 - 24,054,765 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41912,043,818 - 12,497,663 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11912,049,826 - 12,369,988 (-)NCBI
Celera1911,480,096 - 11,923,685 (-)NCBICelera
Cytogenetic Map19p12-p11NCBI
Large1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540541,891,430 - 42,225,066 (-)NCBIChiLan1.0ChiLan1.0
LARGE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12232,137,280 - 32,778,639 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v02214,077,463 - 14,929,250 (-)NCBIMhudiblu_PPA_v0panPan3
LARGE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1029,919,521 - 30,395,787 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11029,875,381 - 30,396,934 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Large1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364926,160,979 - 6,657,491 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LARGE1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11916,080,482 - 16,704,968 (-)NCBI
ChlSab1.1 Ensembl1916,080,430 - 16,549,495 (-)Ensembl
Large1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247501,190,712 - 1,524,051 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 8
Low 10 1 3 4 2 15 2 3 1
Below cutoff 1 1 1

Sequence


Protein Sequences
Protein RefSeqs XP_020937136 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937137 (Get FASTA)   NCBI Sequence Viewer  


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000959 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000001026 UniProtKB/TrEMBL
  ENSSSCP00000040225 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001048 UniProtKB/TrEMBL
  ENSSSCT00000045059 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/TrEMBL
InterPro Glyco_trans_8 UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
NCBI Gene LARGE1 ENTREZGENE
Pfam Glyco_transf_8 UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A480F6A1_PIG UniProtKB/TrEMBL
  F1RYI1_PIG UniProtKB/TrEMBL
VGNC ID VGNC:96402 ENTREZGENE