KCNE4 (potassium voltage-gated channel subfamily E regulatory subunit 4) - Rat Genome Database

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Gene: KCNE4 (potassium voltage-gated channel subfamily E regulatory subunit 4) Sus scrofa
Analyze
Symbol: KCNE4
Name: potassium voltage-gated channel subfamily E regulatory subunit 4
RGD ID: 14014967
Description: ENCODES a protein that exhibits potassium channel inhibitor activity (ortholog); INVOLVED IN membrane repolarization during ventricular cardiac muscle cell action potential (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily E member 4; potassium voltage-gated channel, Isk-related family, member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,912,406 - 124,915,780 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,910,708 - 124,915,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215138,615,216 - 138,619,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNE4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,912,406 - 124,915,780 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,910,708 - 124,915,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215138,615,216 - 138,619,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNE4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,052,190 - 223,055,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,052,190 - 223,198,399 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,916,908 - 223,920,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,625,106 - 223,628,599 (+)NCBINCBI36Build 36hg18NCBI36
Build 342223,742,431 - 223,744,133NCBI
Celera2217,682,314 - 217,685,808 (+)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2215,768,183 - 215,771,892 (+)NCBIHuRef
CHM1_12223,923,002 - 223,926,710 (+)NCBICHM1_1
T2T-CHM13v2.02223,535,022 - 223,538,472 (+)NCBIT2T-CHM13v2.0
Kcne4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,794,628 - 78,797,749 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,794,475 - 78,797,745 (+)EnsemblGRCm39 Ensembl
GRCm38178,816,911 - 78,820,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,816,758 - 78,820,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,813,524 - 78,816,600 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,695,973 - 78,699,049 (+)NCBIMGSCv36mm8
MGSCv36179,687,642 - 79,690,718 (+)NCBIMGSCv36mm8
Cytogenetic Map1C4NCBI
cM Map140.89NCBI
Kcne4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8987,674,264 - 87,699,088 (+)NCBIGRCr8
mRatBN7.2980,243,429 - 80,251,533 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl980,247,379 - 80,250,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,677,383 - 88,678,571 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,792,619 - 93,793,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0992,188,829 - 92,190,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,688,873 - 84,693,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,689,150 - 84,690,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0984,440,098 - 84,448,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4978,200,904 - 78,202,092 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1978,384,322 - 78,385,511 (+)NCBI
Celera977,752,308 - 77,753,496 (+)NCBICelera
Cytogenetic Map9q34NCBI
Kcne4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545310,822,977 - 10,826,191 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545310,822,977 - 10,826,191 (-)NCBIChiLan1.0ChiLan1.0
KCNE4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213125,664,293 - 125,668,275 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B125,679,381 - 125,683,243 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B110,291,194 - 110,294,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B228,869,393 - 228,873,101 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,869,393 - 228,873,101 (+)Ensemblpanpan1.1panPan2
KCNE4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,994,797 - 28,998,596 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3728,996,105 - 28,996,990 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,831,026 - 29,834,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03729,020,674 - 29,024,293 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13728,930,228 - 28,933,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,864,748 - 28,868,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,875,316 - 28,878,940 (+)NCBIUU_Cfam_GSD_1.0
Kcne4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,596,335 - 178,599,723 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,939,511 - 4,942,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,939,477 - 4,942,096 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNE4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,970,868 - 108,973,080 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604090,393,360 - 90,397,358 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcne4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,239,101 - 2,266,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,239,132 - 2,244,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCNE4
134 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 4 19 1 5 14 12 19 3 4 1

Sequence


Ensembl Acc Id: ENSSSCT00000047314   ⟹   ENSSSCP00000033659
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15124,912,406 - 124,915,780 (+)Ensembl
RefSeq Acc Id: XM_005672249   ⟹   XP_005672306
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115124,910,708 - 124,915,787 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005672306   ⟸   XM_005672249
- UniProtKB: A0A286ZPX1 (UniProtKB/TrEMBL),   A0A4X1UBB8 (UniProtKB/TrEMBL),   Q8MIS0 (UniProtKB/TrEMBL),   A0A8D0HQH8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000033659   ⟸   ENSSSCT00000047314


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038149 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015031688 UniProtKB/TrEMBL
  ENSSSCG00025023224 UniProtKB/TrEMBL
  ENSSSCG00030053586 UniProtKB/TrEMBL
  ENSSSCG00035021687 UniProtKB/TrEMBL
  ENSSSCG00040070508 UniProtKB/TrEMBL
  ENSSSCG00045017099 UniProtKB/TrEMBL
  ENSSSCG00050006750 UniProtKB/TrEMBL
  ENSSSCG00055022808 UniProtKB/TrEMBL
  ENSSSCG00060017363 UniProtKB/TrEMBL
  ENSSSCG00065054230 UniProtKB/TrEMBL
  ENSSSCG00070015452 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000047314 ENTREZGENE
  ENSSSCT00000047314.3 UniProtKB/TrEMBL
  ENSSSCT00015041889.1 UniProtKB/TrEMBL
  ENSSSCT00025031464.1 UniProtKB/TrEMBL
  ENSSSCT00030074721.1 UniProtKB/TrEMBL
  ENSSSCT00035028290.1 UniProtKB/TrEMBL
  ENSSSCT00040096745.1 UniProtKB/TrEMBL
  ENSSSCT00045029071.1 UniProtKB/TrEMBL
  ENSSSCT00050009217.1 UniProtKB/TrEMBL
  ENSSSCT00055044823.1 UniProtKB/TrEMBL
  ENSSSCT00060023213.1 UniProtKB/TrEMBL
  ENSSSCT00065074285.1 UniProtKB/TrEMBL
  ENSSSCT00070030335.1 UniProtKB/TrEMBL
InterPro K_chnl_KCNE UniProtKB/TrEMBL
KEGG Report ssc:397167 UniProtKB/TrEMBL
NCBI Gene KCNE4 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 4 UniProtKB/TrEMBL
  PTHR15282 UniProtKB/TrEMBL
Pfam ISK_Channel UniProtKB/TrEMBL
PRINTS KCNECHANNEL UniProtKB/TrEMBL
UniProt A0A286ZPX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UBB8 ENTREZGENE
  A0A8D0HQH8 ENTREZGENE, UniProtKB/TrEMBL
  Q8MIS0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1UBB8 UniProtKB/TrEMBL
VGNC ID VGNC:96387 ENTREZGENE