MGST1 (microsomal glutathione S-transferase 1) - Rat Genome Database

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Gene: MGST1 (microsomal glutathione S-transferase 1) Sus scrofa
Analyze
Symbol: MGST1
Name: microsomal glutathione S-transferase 1
RGD ID: 14013617
Description: ENCODES a protein that exhibits glutathione binding (ortholog); glutathione transferase activity (ortholog); identical protein binding (ortholog); INVOLVED IN glutathione metabolic process (ortholog); Leydig cell differentiation (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN apical part of cell (ortholog); endoplasmic reticulum (ortholog); membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase; microsomal GST-1; microsomal GST-I
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl556,259,557 - 56,283,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1556,259,566 - 56,283,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MGST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl556,259,557 - 56,283,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1556,259,566 - 56,283,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MGST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381216,347,115 - 16,593,331 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1216,347,142 - 16,609,259 (+)EnsemblGRCh38hg38GRCh38
GRCh371216,500,049 - 16,530,126 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361216,391,343 - 16,408,611 (+)NCBINCBI36Build 36hg18NCBI36
Build 341216,391,342 - 16,408,610NCBI
Celera1221,643,859 - 21,661,125 (+)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1216,268,374 - 16,298,400 (+)NCBIHuRef
CHM1_11216,465,087 - 16,495,133 (+)NCBICHM1_1
T2T-CHM13v2.01216,224,568 - 16,466,967 (+)NCBIT2T-CHM13v2.0
Mgst1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396138,117,525 - 138,133,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6138,117,314 - 138,133,753 (+)EnsemblGRCm39 Ensembl
GRCm386138,140,527 - 138,156,755 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6138,140,316 - 138,156,755 (+)EnsemblGRCm38mm10GRCm38
MGSCv376138,089,058 - 138,105,273 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366138,104,733 - 138,120,948 (+)NCBIMGSCv36mm8
Celera6141,204,105 - 141,221,034 (+)NCBICelera
Cytogenetic Map6G1NCBI
cM Map668.4NCBI
Mgst1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84172,760,930 - 172,776,157 (+)NCBIGRCr8
mRatBN7.24171,029,666 - 171,044,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4171,029,630 - 171,044,892 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4177,324,703 - 177,339,950 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04173,108,869 - 173,124,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04171,729,410 - 171,744,649 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04172,119,382 - 172,134,609 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4172,119,331 - 172,134,607 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04236,372,225 - 236,387,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44175,248,654 - 175,263,881 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14175,493,783 - 175,509,005 (+)NCBI
Celera4159,602,240 - 159,617,460 (+)NCBICelera
RH 3.4 Map41032.9RGD
Cytogenetic Map4q44NCBI
Mgst1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541312,989,935 - 13,007,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541312,989,935 - 13,005,203 (+)NCBIChiLan1.0ChiLan1.0
MGST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21021,793,489 - 21,823,123 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11221,790,250 - 21,819,884 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01216,347,737 - 16,383,776 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11216,743,739 - 16,773,290 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1216,743,739 - 16,773,290 (+)Ensemblpanpan1.1panPan2
MGST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12730,370,588 - 30,391,898 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2730,370,594 - 30,391,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2716,055,808 - 16,077,100 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02730,690,546 - 30,712,016 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2730,690,548 - 30,711,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12730,541,771 - 30,563,263 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02730,537,988 - 30,559,272 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02715,775,516 - 15,796,781 (+)NCBIUU_Cfam_GSD_1.0
Mgst1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494591,542,405 - 91,559,526 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365871,269,184 - 1,287,150 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365871,270,030 - 1,287,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,270,588 - 16,300,446 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,277,434 - 16,287,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606919,006,137 - 19,023,047 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgst1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475221,720,012 - 21,737,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475221,722,593 - 21,737,826 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MGST1
211 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 1 23 2 3 3
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000048776   ⟹   ENSSSCP00000038329
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl556,259,568 - 56,282,277 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102195   ⟹   ENSSSCP00000080444
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl556,259,557 - 56,283,965 (-)Ensembl
RefSeq Acc Id: NM_214300   ⟹   NP_999465
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1556,259,566 - 56,283,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091169   ⟹   XP_020946828
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1556,259,720 - 56,283,823 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091170   ⟹   XP_020946829
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1556,259,720 - 56,283,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091171   ⟹   XP_020946830
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1556,259,720 - 56,283,779 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_999465   ⟸   NM_214300
- UniProtKB: P79382 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020946828   ⟸   XM_021091169
- Peptide Label: isoform X1
- UniProtKB: P79382 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020946829   ⟸   XM_021091170
- Peptide Label: isoform X1
- UniProtKB: P79382 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020946830   ⟸   XM_021091171
- Peptide Label: isoform X1
- UniProtKB: P79382 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000038329   ⟸   ENSSSCT00000048776
RefSeq Acc Id: ENSSSCP00000080444   ⟸   ENSSSCT00000102195


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032580 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00005011954 UniProtKB/Swiss-Prot
  ENSSSCG00015003104 UniProtKB/Swiss-Prot
  ENSSSCG00025016137 UniProtKB/Swiss-Prot
  ENSSSCG00030059915 UniProtKB/Swiss-Prot
  ENSSSCG00035038953 UniProtKB/Swiss-Prot
  ENSSSCG00040064750 UniProtKB/Swiss-Prot
  ENSSSCG00045020728 UniProtKB/Swiss-Prot
  ENSSSCG00050034218 UniProtKB/Swiss-Prot
  ENSSSCG00055016266 UniProtKB/Swiss-Prot
  ENSSSCG00060049400 UniProtKB/Swiss-Prot
  ENSSSCG00065045328 UniProtKB/Swiss-Prot
  ENSSSCG00070022772 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000048776 ENTREZGENE
  ENSSSCT00000048776.2 UniProtKB/Swiss-Prot
  ENSSSCT00000102195.1 UniProtKB/TrEMBL
  ENSSSCT00005018533.1 UniProtKB/Swiss-Prot
  ENSSSCT00005018568.1 UniProtKB/Swiss-Prot
  ENSSSCT00015003957.1 UniProtKB/Swiss-Prot
  ENSSSCT00025021694.1 UniProtKB/Swiss-Prot
  ENSSSCT00030083657.1 UniProtKB/Swiss-Prot
  ENSSSCT00035051698.1 UniProtKB/Swiss-Prot
  ENSSSCT00040088442.1 UniProtKB/Swiss-Prot
  ENSSSCT00045035331.1 UniProtKB/Swiss-Prot
  ENSSSCT00045035372.1 UniProtKB/Swiss-Prot
  ENSSSCT00050045888.1 UniProtKB/Swiss-Prot
  ENSSSCT00055032068.1 UniProtKB/Swiss-Prot
  ENSSSCT00060067096.1 UniProtKB/Swiss-Prot
  ENSSSCT00065062036.1 UniProtKB/Swiss-Prot
  ENSSSCT00070045300.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MAPEG-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/Swiss-Prot
  MGST1-like UniProtKB/Swiss-Prot
KEGG Report ssc:397567 UniProtKB/Swiss-Prot
NCBI Gene MGST1 ENTREZGENE
PANTHER MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 UniProtKB/Swiss-Prot
  PTHR10689 UniProtKB/Swiss-Prot
Pfam MAPEG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF161084 UniProtKB/Swiss-Prot
UniProt A0A8W4FNG0_PIG UniProtKB/TrEMBL
  MGST1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:103301 ENTREZGENE